Compile Data Set for Download or QSAR
Report error Found 871 Enz. Inhib. hit(s) with Target = 'Mixed lineage kinase domain-like protein'
TargetMixed lineage kinase domain-like protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataKd:  217nMAssay Description:Binding affinity to human MLKL by kinome scan based methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetMixed lineage kinase domain-like protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50519647(CHEMBL4440337)
Affinity DataKd:  230nMAssay Description:Binding affinity to human MLKL by kinome scan based methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMixed lineage kinase domain-like protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM5832(3-{4-[methyl({2-[(3-sulfamoylphenyl)amino]pyrimidi...)
Affinity DataKd:  9.30E+3nMAssay Description:Binding affinity to MLKL (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMixed lineage kinase domain-like protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50581526(CHEMBL5077278)
Affinity DataKd:  9.33E+5nMAssay Description:Binding affinity to MLKL N-terminal executioner domain (2 to 154 residues)(unknown origin) assessed as dissociation constant by TROSY-HSQC NMR titrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetMixed lineage kinase domain-like protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50581527(CHEMBL5072948)
Affinity DataKd:  3.01E+6nMAssay Description:Binding affinity to MLKL N-terminal executioner domain (2 to 154 residues)(unknown origin) assessed as dissociation constant by TROSY-HSQC NMR titrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetMixed lineage kinase domain-like protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50581528(CHEMBL5070147)
Affinity DataKd:  1.81E+6nMAssay Description:Binding affinity to MLKL N-terminal executioner domain (2 to 154 residues)(unknown origin) assessed as dissociation constant by TROSY-HSQC NMR titrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMixed lineage kinase domain-like protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50581529(CHEMBL5072338)
Affinity DataKd:  8.21E+5nMAssay Description:Binding affinity to MLKL N-terminal executioner domain (2 to 154 residues)(unknown origin) assessed as dissociation constant by TROSY-HSQC NMR titrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetMixed lineage kinase domain-like protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50581530(CHEMBL5086911)
Affinity DataKd:  5.00E+4nMAssay Description:Binding affinity to MLKL N-terminal executioner domain (2 to 154 residues)(unknown origin) assessed as dissociation constant by TROSY-HSQC NMR titrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMixed lineage kinase domain-like protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50581531(CHEMBL5074808)
Affinity DataKd:  3.52E+5nMAssay Description:Binding affinity to MLKL N-terminal executioner domain (2 to 154 residues)(unknown origin) assessed as dissociation constant by TROSY-HSQC NMR titrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetMixed lineage kinase domain-like protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50581532(CHEMBL5091830)
Affinity DataKd:  5.00E+4nMAssay Description:Binding affinity to MLKL N-terminal executioner domain (2 to 154 residues)(unknown origin) assessed as dissociation constant by TROSY-HSQC NMR titrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetMixed lineage kinase domain-like protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50581533(CHEMBL5090828)
Affinity DataKd:  7.30E+4nMAssay Description:Binding affinity to MLKL N-terminal executioner domain (2 to 154 residues)(unknown origin) assessed as dissociation constant by TROSY-HSQC NMR titrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetMixed lineage kinase domain-like protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50581534(CHEMBL1738948)
Affinity DataKd:  5.53E+6nMAssay Description:Binding affinity to MLKL N-terminal executioner domain (2 to 154 residues)(unknown origin) assessed as dissociation constant by TROSY-HSQC NMR titrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetMixed lineage kinase domain-like protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50581530(CHEMBL5086911)
Affinity DataKd:  2.15E+5nMAssay Description:Binding affinity to MLKL N-terminal executioner domain (2 to 154 residues)(unknown origin) assessed as dissociation constant in presence of Nonyl-mal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMixed lineage kinase domain-like protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM5832(3-{4-[methyl({2-[(3-sulfamoylphenyl)amino]pyrimidi...)
Affinity DataKd:  530nMAssay Description:Binding affinity to full length human MLKL pseudokinase domain by Kinomescan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetMixed lineage kinase domain-like protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM5828(1-[2-fluoro-5-(trifluoromethyl)phenyl]-3-{4-[methy...)
Affinity DataKd:  1.80E+3nMAssay Description:Binding affinity to full length human MLKL pseudokinase domain by Kinomescan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetMixed lineage kinase domain-like protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50618991(CHEMBL5421128)
Affinity DataKd:  0.700nMAssay Description:Binding affinity to MLKL (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMixed lineage kinase domain-like protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50618992(CHEMBL5396374)
Affinity DataKd:  150nMAssay Description:Binding affinity to MLKL (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMixed lineage kinase domain-like protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM5832(3-{4-[methyl({2-[(3-sulfamoylphenyl)amino]pyrimidi...)
Affinity DataKd:  530nMAssay Description:Binding affinity to full length MLKL (unknown origin) expressed in human HEK293 cells assessed as dissociation constant incubated for 30 mins by Comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetMixed lineage kinase domain-like protein(Mus musculus)
The Walter and Eliza Hall Institute of Medical Research

Curated by ChEMBL
LigandPNGBDBM5832(3-{4-[methyl({2-[(3-sulfamoylphenyl)amino]pyrimidi...)
Affinity DataKd:  9.30E+3nMAssay Description:Binding affinity to recombinant mouse MLKL pseudokinase domain (179 to 464 residues) expressed in Sf21 insect cells assessed as dissociation constant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMixed lineage kinase domain-like protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM5832(3-{4-[methyl({2-[(3-sulfamoylphenyl)amino]pyrimidi...)
Affinity DataKd:  530nMAssay Description:Binding affinity to full length human MLKL assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetMixed lineage kinase domain-like protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM5828(1-[2-fluoro-5-(trifluoromethyl)phenyl]-3-{4-[methy...)
Affinity DataKd:  1.80E+3nMAssay Description:Binding affinity to full length human MLKL assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetMixed lineage kinase domain-like protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataKd:  217nMAssay Description:Binding affinity to full length MLKL expressed in human HEK293 cells assessed as dissociation constant incubated for 1 hr by ATP-Competition Binding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMixed lineage kinase domain-like protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50519647(CHEMBL4440337)
Affinity DataKd:  230nMAssay Description:Binding affinity to full length MLKL expressed in human HEK293 cells assessed as dissociation constant incubated for 1 hr by ATP-Competition Binding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetMixed lineage kinase domain-like protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM722437(N-(4-(4- amino-1- methyl-7- (pyridin-4- yl)-1H- py...)
Affinity DataKd:  50.5nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetMixed lineage kinase domain-like protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM722438(US20250059188, Compound 2)
Affinity DataKd:  50.5nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetMixed lineage kinase domain-like protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM722447(US20250059188, Compound 3)
Affinity DataKd: <1nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetMixed lineage kinase domain-like protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM722448(N-(4-(4-amino- 7-(1-(2- hydroxyethyl)- 1H- pyrazol...)
Affinity DataKd:  50.5nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetMixed lineage kinase domain-like protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM722462(N-(4-(4-amino- 7-(1-(tetrahydro- 2H-pyran- 4-yl)-1...)
Affinity DataKd: <1nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetMixed lineage kinase domain-like protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM722467(N-(4-(4-amino- 7-(1-(2- hydroxyethyl)- 1H-pyrazol-...)
Affinity DataKd: <1nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetMixed lineage kinase domain-like protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM722516((S)-N-(4-(4-amino- 7-(1-(tetrahydro- 2H-pyran-4-yl...)
Affinity DataKd:  50.5nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetMixed lineage kinase domain-like protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM722517((S)-N-(4-(4- amino-7-(1-methyl-1H- pyrazol-4-yl)fu...)
Affinity DataKd: <1nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetMixed lineage kinase domain-like protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM722518((S)-N-(4-(4- amino-7-(1-(2- hydroxyethyl)-1H- pyra...)
Affinity DataKd: <1nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetMixed lineage kinase domain-like protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM722519(N-(4-{4-amino-1-methyl-1H-pyrazolo[4,3-c]pyridin-3...)
Affinity DataKd:  50.5nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetMixed lineage kinase domain-like protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM722520(N-(4-(4-amino-7-(1-(tetrahydro-2H-pyran-4-yl)-1H-p...)
Affinity DataKd:  50.5nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetMixed lineage kinase domain-like protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM722521(N-(4-(4-amino-7- (1-(2-hydroxyethyl)- 1H-pyrazol-4...)
Affinity DataKd: <1nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetMixed lineage kinase domain-like protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM722522(N-(4-(4-amino- 1-methyl-7-(1- (tetrahydro-2H- pyra...)
Affinity DataKd: <1nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetMixed lineage kinase domain-like protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM722523(N-(4-(4-amino- 1-methyl-7- (pyridin-4- yl)-1H-pyra...)
Affinity DataKd: <1nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetMixed lineage kinase domain-like protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM722524((S)-N-(4-(4-amino-7-(1-(2- hydroxyethyl)-1H-pyrazo...)
Affinity DataKd: <1nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetMixed lineage kinase domain-like protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM722525(N-(4-(4-amino-1- methyl-7-(1-methyl- 1H-pyrazol-4-...)
Affinity DataKd: <1nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetMixed lineage kinase domain-like protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM722526(N-(4-{4-amino-1-methyl-1Hpyrazolo[4,3-c]pyridin-3-...)
Affinity DataKd: <1nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetMixed lineage kinase domain-like protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM722527((S)-N-(4-(4-amino-1-methyl-7- (pyridin-4-yl)-1H-py...)
Affinity DataKd: <1nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetMixed lineage kinase domain-like protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM722528((S)-N-(4-(4-amino-1-methyl-7- (1-(tetrahydro-2H-py...)
Affinity DataKd: <1nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetMixed lineage kinase domain-like protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM722529((S)-N-(4-(4-amino-1-methyl-7- (1-methyl-1H-pyrazol...)
Affinity DataKd: <1nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetMixed lineage kinase domain-like protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM722530((S)-N-(4-(4-amino-1-methyl-7- (1-methyl-1,2,3,6- t...)
Affinity DataKd: <1nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetMixed lineage kinase domain-like protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM722531((S)-N-(4-(4-aminopyrazolo[1,5-a]pyrazin-3-yl)-2-(1...)
Affinity DataKd: <1nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetMixed lineage kinase domain-like protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM722532((S)-N-(4-(4-amino-1-methyl-7- (2-(trifluoromethyl)...)
Affinity DataKd:  50.5nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetMixed lineage kinase domain-like protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM722533((S)-N-(4-(4-amino-1-methyl-7- (2-methylpyridin-4-y...)
Affinity DataKd: <1nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetMixed lineage kinase domain-like protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM722534((S)-N-(4-(4-amino-1-methyl-7- (pyridin-3-yl)-1H-py...)
Affinity DataKd: <1nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetMixed lineage kinase domain-like protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM722535((S)-N-(4-(4-amino-1-methyl-7- (6-methylpyridin-3-y...)
Affinity DataKd: <1nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetMixed lineage kinase domain-like protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM722536((S)-N-(4-(4-amino-7-(2- methoxypyridin-4-yl)-1-met...)
Affinity DataKd:  50.5nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
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