Report error Found 302 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 6'
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
Curated by PubChem BioAssay
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
Curated by PubChem BioAssay
Affinity DataEC50: 5.36E+3nMAssay Description:Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...More data for this Ligand-Target Pair
Affinity DataEC50: 1.03E+3nMAssay Description:Metabotropic glutamate receptors were transiently transfected in HEK293 cells by electroporation as described elsewhere (Brabet I. et al., 1998) and ...More data for this Ligand-Target Pair
Affinity DataEC50: 4.20E+3nMAssay Description:Metabotropic glutamate receptors were transiently transfected in HEK293 cells by electroporation as described elsewhere (Brabet I. et al., 1998) and ...More data for this Ligand-Target Pair
Affinity DataEC50: 4.70E+3nMAssay Description:Metabotropic glutamate receptors were transiently transfected in HEK293 cells by electroporation as described elsewhere (Brabet I. et al., 1998) and ...More data for this Ligand-Target Pair
Affinity DataEC50: 9.00E+3nMAssay Description:Metabotropic glutamate receptors were transiently transfected in HEK293 cells by electroporation as described elsewhere (Brabet I. et al., 1998) and ...More data for this Ligand-Target Pair
Affinity DataEC50: 5.95E+3nMAssay Description:Metabotropic glutamate receptors were transiently transfected in HEK293 cells by electroporation as described elsewhere (Brabet I. et al., 1998) and ...More data for this Ligand-Target Pair
Affinity DataEC50: 1.84E+4nMAssay Description:Metabotropic glutamate receptors were transiently transfected in HEK293 cells by electroporation as described elsewhere (Brabet I. et al., 1998) and ...More data for this Ligand-Target Pair
Affinity DataEC50: 3.80E+3nMAssay Description:Metabotropic glutamate receptors were transiently transfected in HEK293 cells by electroporation as described elsewhere (Brabet I. et al., 1998) and ...More data for this Ligand-Target Pair
Affinity DataEC50: 5.40E+4nMAssay Description:Metabotropic glutamate receptors were transiently transfected in HEK293 cells by electroporation as described elsewhere (Brabet I. et al., 1998) and ...More data for this Ligand-Target Pair
Affinity DataEC50: 2.50E+3nMAssay Description:Metabotropic glutamate receptors were transiently transfected in HEK293 cells by electroporation as described elsewhere (Brabet I. et al., 1998) and ...More data for this Ligand-Target Pair
Affinity DataEC50: 1.30E+4nMAssay Description:Metabotropic glutamate receptors were transiently transfected in HEK293 cells by electroporation as described elsewhere (Brabet I. et al., 1998) and ...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of rat mGlu6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulator activity at rat mGlu6 receptor expressed in HEK293 cells assessed as glutamate-induced GIRK channel-mediated thallium f...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
Curated by PubChem BioAssay
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
Curated by PubChem BioAssay
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of forskolin stimulated cAMP production in RGT cells expressing recombinant human mGluR5aMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+6nMAssay Description:Antagonistic activity against rat (mGluR) metabotropic glutamate receptor 6 stably expressed in chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+6nMAssay Description:Antagonistic activity against rat (mGluR) metabotropic glutamate receptor 6 stably expressed in chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
Curated by PubChem BioAssay
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
Curated by PubChem BioAssay
Affinity DataEC50: 2.43E+3nMAssay Description:Inhibition of forskolin stimulated cAMP production in RGT cells expressing recombinant human mGluR6More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
Curated by PubChem BioAssay
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
Curated by PubChem BioAssay
Affinity DataEC50: 2.99E+3nMAssay Description:Inhibition of forskolin stimulated cAMP production in RGT cells expressing recombinant human mGluR6More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
Curated by PubChem BioAssay
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
Curated by PubChem BioAssay
Affinity DataEC50: 401nMAssay Description:Inhibition of forskolin stimulated cAMP production in RGT cells expressing recombinant human mGluR6More data for this Ligand-Target Pair
Affinity DataEC50: 55nMAssay Description:Metabotropic glutamate receptor 6 agonist activity to influence forskolin stimulated c-AMP formation in rat non neuronal cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 4.00E+4nMAssay Description:Metabotropic glutamate receptor 6 antagonist activity to influence forskolin stimulated c-AMP formation in rat non neuronal cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 3.60E+3nMAssay Description:Metabotropic glutamate receptor 6 agonist activity to influence forskolin stimulated c-AMP formation in rat non neuronal cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 147nMAssay Description:Metabotropic glutamate receptor 6 agonist activity to influence forskolin stimulated c-AMP formation in rat non neuronal cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 600nMAssay Description:Metabotropic glutamate receptor 6 agonist activity to influence forskolin stimulated c-AMP formation in rat non neuronal cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 4.70E+3nMAssay Description:Metabotropic glutamate receptor 6 agonist activity to influence forskolin stimulated c-AMP formation in rat non neuronal cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 1.20E+3nMAssay Description:Metabotropic glutamate receptor 6 agonist activity to influence forskolin stimulated c-AMP formation in rat non neuronal cellsMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:Effective concentration for agonistic activity towards metabotropic glutamate receptor 6 of rat expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:Effective concentration for agonistic activity towards metabotropic glutamate receptor 6 of rat expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
Curated by PubChem BioAssay
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
Curated by PubChem BioAssay
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation at mGluR6 (unknown origin)More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
Curated by PubChem BioAssay
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
Curated by PubChem BioAssay
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation at mGluR6 (unknown origin)More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
Curated by PubChem BioAssay
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
Curated by PubChem BioAssay
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of mGlu6 receptor (unknown origin) relative to controlMore data for this Ligand-Target Pair
Affinity DataEC50: 3.45E+3nMAssay Description:Agonist activity at rat mGluR6 expressed in HEK293 cells assessed as induction of inositol phosphate production by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 6.01E+3nMAssay Description:Agonist activity at rat mGluR6 expressed in HEK293 cells assessed as induction of inositol phosphate production by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 8.22E+4nMAssay Description:Agonist activity at rat mGluR6 expressed in HEK293 cells assessed as induction of inositol phosphate production by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.78E+5nMAssay Description:Activity at rat mGluR6 receptor measured as intracellular calcium concentration in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 1.84E+4nMAssay Description:Activity at rat mGluR6 receptor measured as intracellular calcium concentration in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 2.08E+3nMAssay Description:Agonist activity at rat mGluR6 receptor expressed HEK293 cells assessed as effect on inositol phosphate productionMore data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+5nMAssay Description:Agonist activity at rat mGluR6 receptor expressed HEK293 cells assessed as effect on inositol phosphate productionMore data for this Ligand-Target Pair
Affinity DataEC50: 2.78E+4nMAssay Description:Agonist activity at rat mGluR6 receptor expressed HEK293 cells assessed as effect on inositol phosphate productionMore data for this Ligand-Target Pair
Affinity DataEC50: 730nMAssay Description:Agonist activity at rat mGluR6 receptor expressed HEK293 cells assessed as effect on inositol phosphate productionMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
Curated by PubChem BioAssay
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
Curated by PubChem BioAssay
Affinity DataEC50: 3.41E+3nMAssay Description:Agonist activity at mGlu6 receptor expressed in HEK 293 cells assessed as effect on inositol phosphate productionMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
Curated by PubChem BioAssay
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
Curated by PubChem BioAssay
Affinity DataEC50: 1.11E+5nMAssay Description:Agonist activity at mGlu6 receptor expressed in HEK 293 cells assessed as effect on inositol phosphate productionMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
Curated by PubChem BioAssay
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
Curated by PubChem BioAssay
Affinity DataEC50: >1.00E+6nMAssay Description:Agonist activity at mGlu6 receptor expressed in HEK 293 cells assessed as effect on inositol phosphate productionMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
Curated by PubChem BioAssay
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
Curated by PubChem BioAssay
Affinity DataEC50: 1.95E+3nMAssay Description:Agonist activity at mGlu6 receptor expressed in HEK 293 cells assessed as effect on inositol phosphate productionMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
Curated by PubChem BioAssay
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
Curated by PubChem BioAssay
Affinity DataEC50: 3.45E+3nMAssay Description:Agonist activity at human recombinant mGlu6 receptor expressed in AV12 cells assessed as inhibition of forskolin-stimulated cAMP production after 1 h...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of rat mGlu6 receptor expressed in CHO cells by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of rat mGlu6 receptor expressed in CHO cells by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
Curated by PubChem BioAssay
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
Curated by PubChem BioAssay
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulation of mGluR6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 6.00E+4nMAssay Description:Tested for the agonistic activity against Metabotropic glutamate receptor 6More data for this Ligand-Target Pair
Affinity DataEC50: 2.00E+4nMAssay Description:Tested for the agonistic activity against Metabotropic glutamate receptor 6More data for this Ligand-Target Pair
