Compile Data Set for Download or QSAR
Report error Found 2464 Enz. Inhib. hit(s) with Target = 'Melanocortin receptor 3'
TargetMelanocortin receptor 3(Mouse)
University of Florida

Curated by ChEMBL
LigandPNGBDBM82411(CAS_75921-69-6 | NDP-MSH)
Affinity DataEC50:  75nMAssay Description:Compound was evaluated for its agonist activity on mouse melanocortin receptor 3 (mMC3R) stably expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50131240((S)-5-Guanidino-2-{(S)-2-[(S)-3-(3H-imidazol-4-yl)...)
Affinity DataEC50:  130nMAssay Description:In vitro agonist potency was evaluated in HEK293 cells transfected with human melanocortin receptor (hMC3R)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50131238((S)-2-{(S)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-...)
Affinity DataEC50:  93nMAssay Description:In vitro agonist potency was evaluated in HEK293 cells transfected with human melanocortin receptor (hMC3R)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50131243(N-[(S)-1-((S)-1-{(S)-1-[(S)-1-Carbamoyl-2-(1H-indo...)
Affinity DataEC50:  98nMAssay Description:In vitro agonist potency was evaluated in HEK293 cells transfected with human melanocortin receptor (hMC3R)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50131247((S)-5-Guanidino-2-{(S)-2-[(S)-3-(3H-imidazol-4-yl)...)
Affinity DataEC50:  17nMAssay Description:In vitro agonist potency was evaluated in HEK293 cells transfected with human melanocortin receptor (hMC3R)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50131257((S)-5-Guanidino-2-{(S)-2-[(S)-3-(3H-imidazol-4-yl)...)
Affinity DataEC50:  28nMAssay Description:In vitro agonist potency was evaluated in HEK293 cells transfected with human melanocortin receptor (hMC3R)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50131258((S)-2-{(S)-2-[(S)-2-[2-(4-Chloro-phenyl)-acetylami...)
Affinity DataEC50:  9.30nMAssay Description:In vitro agonist potency was evaluated in HEK293 cells transfected with human melanocortin receptor (hMC3R)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM82411(CAS_75921-69-6 | NDP-MSH)
Affinity DataEC50:  0.360nMAssay Description:In vitro agonist potency was evaluated in HEK293 cells transfected with human melanocortin receptor (hMC3R)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50034910(Ac-His-D-Phe-Arg-D-Trp-NH2 | (S)-2-{(S)-2-[(S)-2-a...)
Affinity DataEC50:  170nMAssay Description:In vitro agonist potency was evaluated in HEK293 cells transfected with human melanocortin receptor (hMC3R)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50131248((S)-5-Guanidino-2-{(S)-2-[(S)-3-(3H-imidazol-4-yl)...)
Affinity DataEC50:  450nMAssay Description:In vitro agonist potency was evaluated in HEK293 cells transfected with human melanocortin receptor (hMC3R)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50131239(2-{(S)-2-[(S)-2-Amino-3-(3H-imidazol-4-yl)-propion...)
Affinity DataEC50:  350nMAssay Description:In vitro agonist potency was evaluated in HEK293 cells transfected with human melanocortin receptor (hMC3R)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50131260((D)-(S)-5-Guanidino-2-{(S)-2-[(S)-2-(2-hydroxy-3-p...)
Affinity DataEC50:  41nMAssay Description:In vitro agonist potency was evaluated in HEK293 cells transfected with human melanocortin receptor (hMC3R)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50131249((S)-5-Guanidino-2-{(S)-2-[(S)-3-(3H-imidazol-4-yl)...)
Affinity DataEC50:  840nMAssay Description:In vitro agonist potency was evaluated in HEK293 cells transfected with human melanocortin receptor (hMC3R)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50029747((4S)-4-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(2S...)
Affinity DataEC50:  1.40nMAssay Description:In vitro cAMP accumulation in HEK cells transfected with human Melanocortin 3 receptor (hMC3R)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50119368((R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic a...)
Affinity DataEC50:  1.40E+3nMAssay Description:In vitro cAMP accumulation in HEK cells transfected with human Melanocortin 3 receptor (hMC3R)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50134488((R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic a...)
Affinity DataEC50: >3.00E+3nMAssay Description:In vitro cAMP accumulation in HEK cells transfected with human Melanocortin 3 receptor (hMC3R)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50134486(1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...)
Affinity DataEC50: >3.00E+3nMAssay Description:In vitro cAMP accumulation in HEK cells transfected with human Melanocortin 3 receptor (hMC3R)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50126086(MT-II cyclic peptide derivative | CHEMBL24892)
Affinity DataEC50:  6nMAssay Description:Agonistic activity against human melanocortin receptor (hMC3R) for cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50184359(MT-II | CHEMBL430239 | Ac-Nle-c[Asp-His-DPhe-Arg-T...)
Affinity DataEC50:  25nMAssay Description:Agonistic activity against human melanocortin receptor (hMC3R) for cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50033131((3R,6S,9R,12S,15S,23R)-15-((S)-2-Acetylamino-hexan...)
Affinity DataKd:  5nMAssay Description:Evaluated for partial agonistic activity at cloned mammalian Melanocortin 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50033134((3R,6S,9R,12S,15S,23R)-15-((S)-2-Acetylamino-hexan...)
Affinity DataEC50:  2.80nMAssay Description:Evaluated for agonist activity at cloned Melanocortin 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50033133((3R,6S,9R,12S,15S,23R)-15-((S)-2-Acetylamino-hexan...)
Affinity DataEC50:  0.191nMAssay Description:Evaluated for agonist activity at cloned Melanocortin 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50029747((4S)-4-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(2S...)
Affinity DataEC50:  0.669nMAssay Description:Evaluated for agonist activity at cloned Melanocortin 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM82411(CAS_75921-69-6 | NDP-MSH)
Affinity DataEC50:  0.132nMAssay Description:Evaluated for agonist activity at cloned Melanocortin 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50033134((3R,6S,9R,12S,15S,23R)-15-((S)-2-Acetylamino-hexan...)
Affinity DataKd:  5nMAssay Description:Evaluated for partial agonistic activity at cloned mammalian Melanocortin 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50033130((3R,6S,9R,12S,15S,23R)-15-((S)-2-Acetylamino-hexan...)
Affinity DataEC50:  0.0630nMAssay Description:Evaluated for agonist activity at cloned Melanocortin 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50033131((3R,6S,9R,12S,15S,23R)-15-((S)-2-Acetylamino-hexan...)
Affinity DataEC50:  1.10nMAssay Description:Evaluated for agonist activity at cloned Melanocortin 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50454555(CHEMBL2115441)
Affinity DataEC50:  28nMAssay Description:Effective concentration that was able to generate 50% maximal intracellular cAMP in L-cells transfected with Melanocortin 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50184359(MT-II | CHEMBL430239 | Ac-Nle-c[Asp-His-DPhe-Arg-T...)
Affinity DataEC50:  0.240nMAssay Description:Effective concentration that was able to generate 50% maximal intracellular cAMP in L-cells transfected with Melanocortin 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50058158((3S,6S,9S,12S,15S,18S,26S)-18-((S)-2-Acetylamino-h...)
Affinity DataEC50:  136nMAssay Description:Effective concentration that was able to generate 50% maximal intracellular cAMP in L-cells transfected with Melanocortin 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM82411(CAS_75921-69-6 | NDP-MSH)
Affinity DataEC50:  4.10nMAssay Description:Effective concentration that was able to generate 50% maximal intracellular cAMP in L-cells transfected with Melanocortin 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50058160((3R,6S,9R,12S,15R,18R,26R)-18-Acetylamino-12-benzy...)
Affinity DataEC50:  89nMAssay Description:Effective concentration that was able to generate 50% maximal intracellular cAMP in L-cells transfected with Melanocortin 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM82411(CAS_75921-69-6 | NDP-MSH)
Affinity DataEC50:  4.10nMAssay Description:effective concentration of peptide at 50% maximal cAMP accumulation on Melanocortin 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50121257(CID44366186 | 6-(2-Acetylamino-hexanoylamino)-20-[...)
Affinity DataEC50: >10nMAssay Description:Agonist potency at human Melanocortin-3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50121260(CID44366183 | 3-(2-Acetylamino-hexanoylamino)-17-[...)
Affinity DataEC50: >10nMAssay Description:Binding affinity against human Melanocortin-3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50001518(CHEMBL2112603)
Affinity DataEC50: >1.00E+4nMAssay Description:Effective concentration of peptide at 50% maximal cAMP generationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50029747((4S)-4-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(2S...)
Affinity DataEC50:  6.70nMAssay Description:Effective concentration of peptide at 50% maximal cAMP generationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50001505(CHEMBL2112604)
Affinity DataEC50: >1.00E+4nMAssay Description:Effective concentration of peptide at 50% maximal cAMP generationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50131877(Ac-c[Cys-Glu-Pro-D-Nal(2')-Arg-Trp-Cys]-Pro-Pro-Ly...)
Affinity DataEC50: >1.00E+4nMAssay Description:Effective concentration of peptide at 50% maximal cAMP generationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50131875(Ac-c[Pen-Glu-His-D-Phe-Arg-Trp-Cys]-Pro-Pro-Lys-As...)
Affinity DataEC50:  2.80nMAssay Description:Effective concentration of peptide at 50% maximal cAMP generationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50131872(Ac-c[Asp-Glu-His-D-Phe-Arg-Trp-Lys]-Pro-Pro-Lys-As...)
Affinity DataEC50: >1.00E+4nMAssay Description:Effective concentration of peptide at 50% maximal cAMP generationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50131878(Ac-c[Cys-Glu-His-D-Nal(2')-Arg-Trp-D-Cys]-Pro-Pro-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Effective concentration of peptide at 50% maximal cAMP generationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50131880(Ac-c[Cys-Glu-His-D-Nal(2')-Arg-Trp-Cys]-Pro-Pro-Ly...)
Affinity DataEC50: >1.00E+4nMAssay Description:Effective concentration of peptide at 50% maximal cAMP generationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50131881(Ac-c[Cys-Glu-Pro-D-Phe-Arg-Trp-Cys]-Pro-Pro-Lys-As...)
Affinity DataEC50:  401nMAssay Description:Effective concentration of peptide at 50% maximal cAMP generationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50001519(CHEMBL2111808)
Affinity DataEC50: >1.00E+4nMAssay Description:Effective concentration of peptide at 50% maximal cAMP generationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50001520(CHEMBL2111807)
Affinity DataEC50: >1.00E+4nMAssay Description:Effective concentration of peptide at 50% maximal cAMP generationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM82411(CAS_75921-69-6 | NDP-MSH)
Affinity DataEC50:  0.800nMAssay Description:Effective concentration of peptide at 50% maximal cAMP generationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50152280(Pyridine-2-carboxylic acid [(S)-1-((S)-1-{(S)-1-[(...)
Affinity DataEC50:  452nMAssay Description:Agonistic activity against human Melanocortin 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50152255(2-{(S)-2-[(S)-3-(4-Chloro-phenyl)-2-(furan-2-ylami...)
Affinity DataEC50:  913nMAssay Description:Agonistic activity against human Melanocortin 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50152272(N-[(S)-1-((S)-1-{(S)-1-[(S)-1-Carbamoyl-2-(1H-indo...)
Affinity DataEC50:  992nMAssay Description:Agonistic activity against human Melanocortin 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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