Compile Data Set for Download or QSAR
Report error Found 198 Enz. Inhib. hit(s) with Target = 'Melanin-concentrating hormone receptor 2'
LigandPNGBDBM50360702(CHEMBL1934121)
Affinity DataIC50: 0.100nMAssay Description:Antagonist activity at human MCHR2 receptor expressed in CHO cells assessed as inhibition of MCH-stimulated Ca2+ flux preincubated for 10 mins prior ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
LigandPNGBDBM50360704(CHEMBL1934123)
Affinity DataIC50: 0.100nMAssay Description:Antagonist activity at human MCHR2 receptor expressed in CHO cells assessed as inhibition of MCH-stimulated Ca2+ flux preincubated for 10 mins prior ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
LigandPNGBDBM50360708(CHEMBL1934127)
Affinity DataIC50: 1nMAssay Description:Antagonist activity at human MCHR2 receptor expressed in CHO cells assessed as inhibition of MCH-stimulated Ca2+ flux preincubated for 10 mins prior ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
LigandPNGBDBM50360683(CHEMBL1934130)
Affinity DataIC50: 1nMAssay Description:Antagonist activity at human MCHR2 receptor expressed in CHO cells assessed as inhibition of MCH-stimulated Ca2+ flux preincubated for 10 mins prior ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
LigandPNGBDBM50172440(2-(2,4-Dichloro-phenoxy)-N-(4-methyl-2-piperazin-1...)
Affinity DataIC50: 3.70nMAssay Description:Displacement of 15 pM [125I]-MCH from human MCH2R expressed in CHO-K1 in whole-cell binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50360691(CHEMBL1934109)
Affinity DataIC50: 4nMAssay Description:Antagonist activity at human MCHR2 receptor expressed in CHO cells assessed as inhibition of MCH-stimulated Ca2+ flux preincubated for 10 mins prior ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
LigandPNGBDBM50360694(CHEMBL1934112)
Affinity DataIC50: 4nMAssay Description:Antagonist activity at human MCHR2 receptor expressed in CHO cells assessed as inhibition of MCH-stimulated Ca2+ flux preincubated for 10 mins prior ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
LigandPNGBDBM50172432(2-(2,4-Dichloro-phenoxy)-N-{2-[(2-dimethylamino-et...)
Affinity DataIC50: 4.5nMAssay Description:Displacement of 15 pM [125I]-MCH from human MCH2R expressed in CHO-K1 in whole-cell binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50172425(N-[2-(4-Amino-piperidin-1-yl)-4-methyl-quinolin-6-...)
Affinity DataIC50: 4.70nMAssay Description:Displacement of 15 pM [125I]-MCH from human MCH2R expressed in CHO-K1 in whole-cell binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50172418(N-[4-Methyl-2-(4-pyrrolidin-1-yl-piperidin-1-yl)-q...)
Affinity DataIC50: 6.30nMAssay Description:Displacement of 15 pM [125I]-MCH from human MCH2R expressed in CHO-K1 in whole-cell binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50172441((E)-N-{2-[(2-Hydroxy-ethyl)-methyl-amino]-4-methyl...)
Affinity DataIC50: 6.40nMAssay Description:Displacement of 15 pM [125I]-MCH from human MCH2R expressed in CHO-K1 in whole-cell binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50172413(2-(2,4-Dichloro-phenoxy)-N-{4-methyl-2-[methyl-(2-...)
Affinity DataIC50: 6.80nMAssay Description:Displacement of 15 pM [125I]-MCH from human MCH2R expressed in CHO-K1 in whole-cell binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50172416(N-[2-(2,5-Diaza-bicyclo[2.2.1]hept-2-yl)-4-methyl-...)
Affinity DataIC50: 6.80nMAssay Description:Displacement of 15 pM [125I]-MCH from human MCH2R expressed in CHO-K1 in whole-cell binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50172427(N-[2-(3-Dimethylamino-propylamino)-4-methyl-quinol...)
Affinity DataIC50: 7.10nMAssay Description:Displacement of 15 pM [125I]-MCH from human MCH2R expressed in CHO-K1 in whole-cell binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50360706(CHEMBL1934125)
Affinity DataIC50: 8nMAssay Description:Antagonist activity at human MCHR2 receptor expressed in CHO cells assessed as inhibition of MCH-stimulated Ca2+ flux preincubated for 10 mins prior ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
LigandPNGBDBM50172442((E)-N-[2-(2-Dimethylamino-ethylamino)-4-methyl-qui...)
Affinity DataIC50: 8.40nMAssay Description:Displacement of 15 pM [125I]-MCH from human MCH2R expressed in CHO-K1 in whole-cell binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50172414(2-(2,4-Dichloro-phenoxy)-N-[2-(2-dimethylamino-eth...)
Affinity DataIC50: 8.70nMAssay Description:Displacement of 15 pM [125I]-MCH from human MCH2R expressed in CHO-K1 in whole-cell binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50172430((E)-N-(4-Methyl-2-piperazin-1-yl-quinolin-6-yl)-3-...)
Affinity DataIC50: 10nMAssay Description:Displacement of 15 pM [125I]-MCH from human MCH2R expressed in CHO-K1 in whole-cell binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50172424(N-(4-Methyl-2-morpholin-4-yl-quinolin-6-yl)-2-(4-t...)
Affinity DataIC50: 10nMAssay Description:Displacement of 15 pM [125I]-MCH from human MCH2R expressed in CHO-K1 in whole-cell binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50172438(N-{2-[(1-Ethyl-pyrrolidin-2-ylmethyl)-amino]-4-met...)
Affinity DataIC50: 10nMAssay Description:Displacement of 15 pM [125I]-MCH from human MCH2R expressed in CHO-K1 in whole-cell binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50150709(2-(2,4-Dichloro-phenoxy)-N-[4-methyl-2-(4-methyl-p...)
Affinity DataIC50: 10nMAssay Description:Displacement of 15 pM [125I]-MCH from human MCH2R expressed in CHO-K1 in whole-cell binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50172434(Acetic acid 2-({6-[2-(3,4-dichloro-phenoxy)-acetyl...)
Affinity DataIC50: 10nMAssay Description:Displacement of 15 pM [125I]-MCH from human MCH2R expressed in CHO-K1 in whole-cell binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50172415(2-(2,4-Dichloro-phenoxy)-N-{2-[(2-hydroxy-ethyl)-m...)
Affinity DataIC50: 10nMAssay Description:Displacement of 15 pM [125I]-MCH from human MCH2R expressed in CHO-K1 in whole-cell binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50360697(CHEMBL1934116)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at human MCHR2 receptor expressed in CHO cells assessed as inhibition of MCH-stimulated Ca2+ flux preincubated for 10 mins prior ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
LigandPNGBDBM50360707(CHEMBL1934126)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at human MCHR2 receptor expressed in CHO cells assessed as inhibition of MCH-stimulated Ca2+ flux preincubated for 10 mins prior ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
LigandPNGBDBM50360709(CHEMBL1934128)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at human MCHR2 receptor expressed in CHO cells assessed as inhibition of MCH-stimulated Ca2+ flux preincubated for 10 mins prior ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
LigandPNGBDBM50301708((Z)-1'-((6-((3,4-difluorophenyl)(ethoxyimino)methy...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human MCH2RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
LigandPNGBDBM50360703(CHEMBL1934122)
Affinity DataIC50: 13nMAssay Description:Antagonist activity at human MCHR2 receptor expressed in CHO cells assessed as inhibition of MCH-stimulated Ca2+ flux preincubated for 10 mins prior ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
LigandPNGBDBM50360696(CHEMBL1934114)
Affinity DataIC50: 30nMAssay Description:Antagonist activity at human MCHR2 receptor expressed in CHO cells assessed as inhibition of MCH-stimulated Ca2+ flux preincubated for 10 mins prior ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
LigandPNGBDBM50360690(CHEMBL1934108)
Affinity DataIC50: 70nMAssay Description:Antagonist activity at human MCHR2 receptor expressed in CHO cells assessed as inhibition of MCH-stimulated Ca2+ flux preincubated for 10 mins prior ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
LigandPNGBDBM50360698(CHEMBL1934117)
Affinity DataIC50: 80nMAssay Description:Antagonist activity at human MCHR2 receptor expressed in CHO cells assessed as inhibition of MCH-stimulated Ca2+ flux preincubated for 10 mins prior ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
LigandPNGBDBM50360689(CHEMBL1934107)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at human MCHR2 receptor expressed in CHO cells assessed as inhibition of MCH-stimulated Ca2+ flux preincubated for 10 mins prior ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
LigandPNGBDBM50360695(CHEMBL1934113)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at human MCHR2 receptor expressed in CHO cells assessed as inhibition of MCH-stimulated Ca2+ flux preincubated for 10 mins prior ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
LigandPNGBDBM50360700(CHEMBL1934119)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at human MCHR2 receptor expressed in CHO cells assessed as inhibition of MCH-stimulated Ca2+ flux preincubated for 10 mins prior ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
LigandPNGBDBM50360699(CHEMBL1934118)
Affinity DataIC50: 150nMAssay Description:Antagonist activity at human MCHR2 receptor expressed in CHO cells assessed as inhibition of MCH-stimulated Ca2+ flux preincubated for 10 mins prior ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
LigandPNGBDBM50360693(CHEMBL1934111)
Affinity DataIC50: 200nMAssay Description:Antagonist activity at human MCHR2 receptor expressed in CHO cells assessed as inhibition of MCH-stimulated Ca2+ flux preincubated for 10 mins prior ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
LigandPNGBDBM50360711(CHEMBL1934115)
Affinity DataIC50: 200nMAssay Description:Antagonist activity at human MCHR2 receptor expressed in CHO cells assessed as inhibition of MCH-stimulated Ca2+ flux preincubated for 10 mins prior ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
LigandPNGBDBM50360701(CHEMBL1934120)
Affinity DataIC50: 250nMAssay Description:Antagonist activity at human MCHR2 receptor expressed in CHO cells assessed as inhibition of MCH-stimulated Ca2+ flux preincubated for 10 mins prior ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
LigandPNGBDBM50360705(CHEMBL1934124)
Affinity DataIC50: 250nMAssay Description:Antagonist activity at human MCHR2 receptor expressed in CHO cells assessed as inhibition of MCH-stimulated Ca2+ flux preincubated for 10 mins prior ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
LigandPNGBDBM50360692(CHEMBL1934110)
Affinity DataIC50: 300nMAssay Description:Antagonist activity at human MCHR2 receptor expressed in CHO cells assessed as inhibition of MCH-stimulated Ca2+ flux preincubated for 10 mins prior ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
LigandPNGBDBM50360710(CHEMBL1934129)
Affinity DataIC50: 678nMAssay Description:Antagonist activity at human MCHR2 receptor expressed in CHO cells assessed as inhibition of MCH-stimulated Ca2+ flux preincubated for 10 mins prior ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
LigandPNGBDBM50193608((E)-N-(4-(cyclobutylamino)-2-propylquinolin-6-yl)-...)
Affinity DataIC50: 960nMAssay Description:Displacement of 125I-[Phe13,Tyr19]-MCH from human MCH-R2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50258478(2-(3,4-difluorophenyl)-N-(3-(6-fluoro-1H-spiro[fur...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity to MCHR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50360684(CHEMBL1934102)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human MCHR2 receptor expressed in CHO cells assessed as inhibition of MCH-stimulated Ca2+ flux preincubated for 10 mins prior ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
LigandPNGBDBM50153204(N-[2-(4-Benzyl-piperazin-1-yl)-ethyl]-4-[3-(4-phen...)
Affinity DataIC50: 2.88E+3nMAssay Description:Binding affinity against human Melanin-concentrating hormone receptor 2 stably transfected CHO cells was determined using [125I]MCH as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50296043(N-((5-chloro-6-oxo-1,6-dihydropyridin-3-yl)(4-fluo...)
Affinity DataIC50: 4.60E+3nMAssay Description:Displacement of [125I]MCH from human MCHR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
LigandPNGBDBM50153210(N-(1-Ethyl-pyrrolidin-2-ylmethyl)-4-[3-(4-phenoxy-...)
Affinity DataIC50: 6.31E+3nMAssay Description:Binding affinity against human Melanin-concentrating hormone receptor 2 stably transfected CHO cells was determined using [125I]MCH as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50153220(2-Methoxy-4-[3-(3-phenylamino-phenyl)-ureido]-N-(3...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity against human Melanin-concentrating hormone receptor 2 stably transfected CHO cells was determined using [125I]MCH as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50153206(2-Methoxy-4-[3-(4-phenoxy-phenyl)-ureido]-N-(3-pip...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity against human Melanin-concentrating hormone receptor 2 stably transfected CHO cells was determined using [125I]MCH as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50201273(N-(1-(6,7-dihydro-5H-indeno[5,6-d][1,3]dioxol-5-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Affinity for MCH-R2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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