Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with Target = 'Macrophage colony-stimulating factor 1 receptor [538-678,753-922]'
TargetMacrophage colony-stimulating factor 1 receptor [538-678,753-922](Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 49nMpH: 7.5 T: 2°CAssay Description:The full-length cFMS cytoplasmic domain (FMS.538-972.6His) or chimera was incubated with compound in reaction buffer. Control reactions were run in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor [538-678,753-922](Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 57nMpH: 7.5 T: 2°CAssay Description:The full-length cFMS cytoplasmic domain (FMS.538-972.6His) or chimera was incubated with compound in reaction buffer. Control reactions were run in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor [538-678,753-922](Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM17749(JNJ31117164)
Affinity DataIC50: 1.20E+3nMpH: 7.5 T: 2°CAssay Description:The full-length cFMS cytoplasmic domain (FMS.538-972.6His) or chimera was incubated with compound in reaction buffer. Control reactions were run in e...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor [538-678,753-922](Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM17015(CHEMBL86755 | Indolinone based inhibitor, 1 | (3Z)...)
Affinity DataIC50: 1.30E+3nMpH: 7.5 T: 2°CAssay Description:The full-length cFMS cytoplasmic domain (FMS.538-972.6His) or chimera was incubated with compound in reaction buffer. Control reactions were run in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor [538-678,753-922](Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM17749(JNJ31117164)
Affinity DataIC50: 1.30E+3nMpH: 7.5 T: 2°CAssay Description:The full-length cFMS cytoplasmic domain (FMS.538-972.6His) or chimera was incubated with compound in reaction buffer. Control reactions were run in e...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor [538-678,753-922](Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM17015(CHEMBL86755 | Indolinone based inhibitor, 1 | (3Z)...)
Affinity DataIC50: 1.40E+3nMpH: 7.5 T: 2°CAssay Description:The full-length cFMS cytoplasmic domain (FMS.538-972.6His) or chimera was incubated with compound in reaction buffer. Control reactions were run in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor [538-678,753-922](Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM4363(alpha-Cyano-(3,4-dihydroxy)thiocinnamide | CHEMBL7...)
Affinity DataIC50: 3.00E+3nMpH: 7.5 T: 2°CAssay Description:The full-length cFMS cytoplasmic domain (FMS.538-972.6His) or chimera was incubated with compound in reaction buffer. Control reactions were run in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor [538-678,753-922](Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM4363(alpha-Cyano-(3,4-dihydroxy)thiocinnamide | CHEMBL7...)
Affinity DataIC50: 3.30E+3nMpH: 7.5 T: 2°CAssay Description:The full-length cFMS cytoplasmic domain (FMS.538-972.6His) or chimera was incubated with compound in reaction buffer. Control reactions were run in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor [538-678,753-922](Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM17747(CHEMBL328710 | (3Z)-3-{[4-(dimethylamino)phenyl]me...)
Affinity DataIC50: 3.90E+3nMpH: 7.5 T: 2°CAssay Description:The full-length cFMS cytoplasmic domain (FMS.538-972.6His) or chimera was incubated with compound in reaction buffer. Control reactions were run in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor [538-678,753-922](Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM7393(Indirubin-3 -monoxime | 3-[(2Z,3E)-3-(hydroxyimino...)
Affinity DataIC50: 4.20E+3nMpH: 7.5 T: 2°CAssay Description:The full-length cFMS cytoplasmic domain (FMS.538-972.6His) or chimera was incubated with compound in reaction buffer. Control reactions were run in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor [538-678,753-922](Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM7393(Indirubin-3 -monoxime | 3-[(2Z,3E)-3-(hydroxyimino...)
Affinity DataIC50: 4.50E+3nMpH: 7.5 T: 2°CAssay Description:The full-length cFMS cytoplasmic domain (FMS.538-972.6His) or chimera was incubated with compound in reaction buffer. Control reactions were run in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor [538-678,753-922](Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM17747(CHEMBL328710 | (3Z)-3-{[4-(dimethylamino)phenyl]me...)
Affinity DataIC50: 4.60E+3nMpH: 7.5 T: 2°CAssay Description:The full-length cFMS cytoplasmic domain (FMS.538-972.6His) or chimera was incubated with compound in reaction buffer. Control reactions were run in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor [538-678,753-922](Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM17748(2-(3,4-Dihydroxyphenyl)-6,7-dimethylquinoxaline | ...)
Affinity DataIC50: 8.30E+3nMpH: 7.5 T: 2°CAssay Description:The full-length cFMS cytoplasmic domain (FMS.538-972.6His) or chimera was incubated with compound in reaction buffer. Control reactions were run in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor [538-678,753-922](Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM17748(2-(3,4-Dihydroxyphenyl)-6,7-dimethylquinoxaline | ...)
Affinity DataIC50: 9.40E+3nMpH: 7.5 T: 2°CAssay Description:The full-length cFMS cytoplasmic domain (FMS.538-972.6His) or chimera was incubated with compound in reaction buffer. Control reactions were run in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed