Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with Target = 'Lysyl oxidase homolog 3'
TargetLysyl oxidase homolog 3(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50505638(CHEMBL4457578)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant C-terminal His-tagged human LOXL3 (1 to 753 residues) expressed in CHO cells using putrescine as substrate preincubated wit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetLysyl oxidase homolog 3(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50058655(1,1',1'',1'''-[disulfanediylbis(carbonothioylnitri...)
Affinity DataIC50: 93nMAssay Description:Inhibition of recombinant human LOXL3 expressed in CHO cells using diaminopentane as substrate preincubated for 30 mins followed by substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetLysyl oxidase homolog 3(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM43362(TETRAMETHYLTHIURAM DISULFIDE | SMR000059023 | MLS0...)
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant human LOXL3 expressed in CHO cells using diaminopentane as substrate preincubated for 30 mins followed by substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetLysyl oxidase homolog 3(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50232678(CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...)
Affinity DataIC50: 170nMAssay Description:Inhibition of recombinant human LOXL3 expressed in CHO cells using diaminopentane as substrate preincubated for 30 mins followed by substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetLysyl oxidase homolog 3(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50232679(CHEMBL4068784 | US11358936, Compound 4-5)
Affinity DataIC50: 214nMAssay Description:Inhibition of recombinant human C-terminal His10-tagged LOXL3 (1 to 753 residues) assessed as reduction in H2O2 production using DAP as substrate pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2019
Entry Details Article
PubMed
TargetLysyl oxidase homolog 3(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM633249(N-((1-(4-(((1-((Z)-4-amino-2-fluorobut-2-en-1-yl)-...)
Affinity DataIC50: 300nMAssay Description:The assay was developed using either 384 or 96 well format. Briefly, in a standard 384 well plate assay 25 μL of a dilution of any of the isoenz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
Go to US Patent

TargetLysyl oxidase homolog 3(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM633246((3aS,3a'S,4S,4'S,6aR,6a′R)-4,4′-(((((5...)
Affinity DataIC50: 300nMAssay Description:The assay was developed using either 384 or 96 well format. Briefly, in a standard 384 well plate assay 25 μL of a dilution of any of the isoenz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
Go to US Patent

TargetLysyl oxidase homolog 3(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50232678(CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...)
Affinity DataIC50: 310nMAssay Description:Inhibition of recombinant C-terminal His-tagged human LOXL3 (1 to 753 residues) expressed in CHO cells using cadaverine hydrochloride as substrate pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetLysyl oxidase homolog 3(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50526727(CHEMBL4568508 | US10807974, Example 100 | US109950...)
Affinity DataIC50: 860nMAssay Description:Inhibition of recombinant C-terminal His-tagged human LOXL3 (1 to 753 residues) expressed in CHO cells using cadaverine hydrochloride as substrate pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetLysyl oxidase homolog 3(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50266786(CHEMBL4063337)
Affinity DataIC50: 1.17E+3nMAssay Description:Inhibition of recombinant human LOXL3 assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details Article
PubMed
TargetLysyl oxidase homolog 3(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM461421(US10774069, Compound 1 | US11072585, Example 120 |...)
Affinity DataIC50: 1.21E+3nMAssay Description:Table 9: The amine oxidase activity was evaluated by measuring Amplex Red fluorescence using commercially available purified, recombinant human LOXL3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2023
Entry Details
Go to US Patent

TargetLysyl oxidase homolog 3(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50266787(CHEMBL4092740)
Affinity DataIC50: 1.22E+3nMAssay Description:Inhibition of recombinant human LOXL3 assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details Article
PubMed
TargetLysyl oxidase homolog 3(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50526722(CHEMBL4457897)
Affinity DataIC50: 1.22E+3nMAssay Description:Inhibition of recombinant C-terminal His-tagged human LOXL3 (1 to 753 residues) expressed in CHO cells using cadaverine hydrochloride as substrate pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetLysyl oxidase homolog 3(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50526721(CHEMBL4444163 | US10807974, Example 111 | US109950...)
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of recombinant C-terminal His-tagged human LOXL3 (1 to 753 residues) expressed in CHO cells using cadaverine hydrochloride as substrate pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetLysyl oxidase homolog 3(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50463622(CHEMBL4245637)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of recombinant human LOXL3 expressed in CHO cells using diaminopentane as substrate preincubated for 30 mins followed by substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetLysyl oxidase homolog 3(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50266822(CHEMBL4079398)
Affinity DataIC50: 1.38E+3nMAssay Description:Inhibition of recombinant human LOXL3 assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details Article
PubMed
TargetLysyl oxidase homolog 3(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50463620(CHEMBL4240937)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of recombinant human LOXL3 expressed in CHO cells using diaminopentane as substrate preincubated for 30 mins followed by substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetLysyl oxidase homolog 3(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50526742(CHEMBL4441069)
Affinity DataIC50: 3.85E+3nMAssay Description:Inhibition of recombinant C-terminal His-tagged human LOXL3 (1 to 753 residues) expressed in CHO cells using cadaverine hydrochloride as substrate pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetLysyl oxidase homolog 3(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50526720(CHEMBL4550042)
Affinity DataIC50: 3.86E+3nMAssay Description:Inhibition of recombinant C-terminal His-tagged human LOXL3 (1 to 753 residues) expressed in CHO cells using cadaverine hydrochloride as substrate pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetLysyl oxidase homolog 3(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50463614(CHEMBL4237334)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human LOXL3 expressed in CHO cells using diaminopentane as substrate preincubated for 30 mins followed by substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetLysyl oxidase homolog 3(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50463617(CHEMBL4238380)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human LOXL3 expressed in CHO cells using diaminopentane as substrate preincubated for 30 mins followed by substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetLysyl oxidase homolog 3(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50526726(CHEMBL4574361)
Affinity DataIC50: 6.69E+3nMAssay Description:Inhibition of recombinant C-terminal His-tagged human LOXL3 (1 to 753 residues) expressed in CHO cells using cadaverine hydrochloride as substrate pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetLysyl oxidase homolog 3(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50526731(CHEMBL4564074 | US10807974, Example 103 | US109950...)
Affinity DataIC50: 6.78E+3nMAssay Description:Inhibition of recombinant C-terminal His-tagged human LOXL3 (1 to 753 residues) expressed in CHO cells using cadaverine hydrochloride as substrate pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetLysyl oxidase homolog 3(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50526743(CHEMBL4551909)
Affinity DataIC50: 9.31E+3nMAssay Description:Inhibition of recombinant C-terminal His-tagged human LOXL3 (1 to 753 residues) expressed in CHO cells using cadaverine hydrochloride as substrate pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetLysyl oxidase homolog 3(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50366038(CHEMBL1356238)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of recombinant human LOXL3 expressed in CHO cells using diaminopentane as substrate preincubated for 30 mins followed by substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetLysyl oxidase homolog 3(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50463618(CHEMBL4241062)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of recombinant human LOXL3 expressed in CHO cells using diaminopentane as substrate preincubated for 30 mins followed by substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetLysyl oxidase homolog 3(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50501885(CHEMBL4441173 | US10807974, Example 68 | US1099508...)
Affinity DataIC50: 1.35E+4nMAssay Description:Inhibition of recombinant C-terminal His-tagged human LOXL3 (1 to 753 residues) expressed in CHO cells using cadaverine hydrochloride as substrate pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetLysyl oxidase homolog 3(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50463613(CHEMBL1927732)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of recombinant human LOXL3 expressed in CHO cells using diaminopentane as substrate preincubated for 30 mins followed by substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetLysyl oxidase homolog 3(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50526728(CHEMBL4463882 | US10807974, Example 155 | US109950...)
Affinity DataIC50: 2.42E+4nMAssay Description:Inhibition of recombinant C-terminal His-tagged human LOXL3 (1 to 753 residues) expressed in CHO cells using cadaverine hydrochloride as substrate pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetLysyl oxidase homolog 3(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50463619(CHEMBL4242081)
Affinity DataIC50: 5.70E+4nMAssay Description:Inhibition of recombinant human LOXL3 expressed in CHO cells using diaminopentane as substrate preincubated for 30 mins followed by substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetLysyl oxidase homolog 3(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50463621(CHEMBL3144916)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human LOXL3 expressed in CHO cells using diaminopentane as substrate preincubated for 30 mins followed by substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetLysyl oxidase homolog 3(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50463616(CHEMBL4241417)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human LOXL3 expressed in CHO cells using diaminopentane as substrate preincubated for 30 mins followed by substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetLysyl oxidase homolog 3(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50463615(CHEMBL4251179)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human LOXL3 expressed in CHO cells using diaminopentane as substrate preincubated for 30 mins followed by substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed