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Report error Found 43 Enz. Inhib. hit(s) with Target = 'Lymphocyte antigen 96'
TargetLymphocyte antigen 96(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50157621(CHEMBL3787558)
Affinity DataKon:  1.22M-1s-1Assay Description:Binding affinity to recombinant human MD2 (17 to 160 residues) expressed in Escherichia coli BL21(DE3) cells by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetLymphocyte antigen 96(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50587262(CHEMBL3601750)
Affinity DataKd:  3.60E+3nMAssay Description:Binding affinity to MD2 (unknown origin) assessed as dissociation constant by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetLymphocyte antigen 96(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50587261(CHEMBL5075055)
Affinity DataKd:  3.20E+3nMAssay Description:Binding affinity to MD2 (unknown origin) assessed as dissociation constant by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetLymphocyte antigen 96(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50525782(CHEMBL4546657)
Affinity DataKd:  1.40E+5nMAssay Description:Binding affinity to recombinant human MD2 by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetLymphocyte antigen 96(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50525781(CHEMBL4539269)
Affinity DataKd:  2.70E+6nMAssay Description:Binding affinity to recombinant human MD2 by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetLymphocyte antigen 96(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50525780(CHEMBL4452033)
Affinity DataKd:  2.94E+4nMAssay Description:Binding affinity to recombinant human MD2 by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetLymphocyte antigen 96(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50515276(CHEMBL4463337)
Affinity DataKd:  4.90nMAssay Description:Binding affinity to recombinant human MD2 assessed as dissociation constant up to 200 uM by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetLymphocyte antigen 96(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50515277(CHEMBL4436411)
Affinity DataKd:  2.40nMAssay Description:Binding affinity to recombinant human MD2 assessed as dissociation constant up to 200 uM by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetLymphocyte antigen 96(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50501804(CHEMBL4517719)
Affinity DataKd:  1.85E+5nMAssay Description:Binding affinity to recombinant human 10His-tagged MD2 (Glu17 to Asn160 residues) expressed in Escherichia coli by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetLymphocyte antigen 96(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50277589(CHEMBL4162528)
Affinity DataKon:  0.703M-1s-1Assay Description:Binding affinity to MD2 (unknown origin) by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2020
Entry Details Article
PubMed
TargetLymphocyte antigen 96(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50277588(CHEMBL4176576)
Affinity DataKd:  1.89E+5nMAssay Description:Binding affinity to MD2 (unknown origin) by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2020
Entry Details Article
PubMed
TargetLymphocyte antigen 96(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50277590(CHEMBL4164940)
Affinity DataKon:  0.695M-1s-1Assay Description:Binding affinity to MD2 (unknown origin) by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2020
Entry Details Article
PubMed
TargetLymphocyte antigen 96(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50277588(CHEMBL4176576)
Affinity DataKon:  1.10M-1s-1Assay Description:Binding affinity to MD2 (unknown origin) by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2020
Entry Details Article
PubMed
TargetLymphocyte antigen 96(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50277590(CHEMBL4164940)
Affinity DataKd:  8.40E+4nMAssay Description:Binding affinity to MD2 (unknown origin) by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2020
Entry Details Article
PubMed
TargetLymphocyte antigen 96(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50277589(CHEMBL4162528)
Affinity DataKd:  1.25E+5nMAssay Description:Binding affinity to MD2 (unknown origin) by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2020
Entry Details Article
PubMed
TargetLymphocyte antigen 96(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM43491(MLS000860258 | 3,5-di(3,4,5-trimethoxybenzylidene)...)
Affinity DataKd:  7.11E+4nMAssay Description:Binding affinity to recombinant human MD2 by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetLymphocyte antigen 96(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50284547(CHEMBL4161646)
Affinity DataKd:  3.20E+4nMAssay Description:Binding affinity to human recombinant MD2 by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2020
Entry Details Article
PubMed
TargetLymphocyte antigen 96(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50157621(CHEMBL3787558)
Affinity DataKd:  3.40E+4nMAssay Description:Binding affinity to recombinant human MD2 (17 to 160 residues) expressed in Escherichia coli BL21(DE3) cells by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetLymphocyte antigen 96(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50140172(CHEBI:3962 | CHEMBL140 | Curcumin | US9409845, Tab...)
Affinity DataKd:  3.79E+5nMAssay Description:Binding affinity to recombinant human MD2 (17 to 160 residues) expressed in Escherichia coli BL21(DE3) cells by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetLymphocyte antigen 96(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50384998(XANTHOHUMOL | CVD-0019905)
Affinity DataKd:  4.60E+5nMAssay Description:Binding affinity to recombinant human MD2 (17 to 160 residues) expressed in Escherichia coli BL21(DE3) cells by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetLymphocyte antigen 96(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50255632(CHEMBL4100044)
Affinity DataKd:  3.00E+3nMAssay Description:Binding to C-terminal His6-tagged human MD2 expressed in Pichia pastoris GS115 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetLymphocyte antigen 96(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50255625(CHEMBL4070714)
Affinity DataKd:  1.40E+4nMAssay Description:Binding to C-terminal His6-tagged human MD2 expressed in Pichia pastoris GS115 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetLymphocyte antigen 96(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50255626(CHEMBL4069693)
Affinity DataKd:  2.20E+4nMAssay Description:Binding to C-terminal His6-tagged human MD2 expressed in Pichia pastoris GS115 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetLymphocyte antigen 96(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50458115(CHEMBL1224773)
Affinity DataKd:  5.95E+4nMAssay Description:Binding affinity to recombinant human MD2 by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetLymphocyte antigen 96(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50271263(CHEMBL4125910)
Affinity DataKd:  650nMAssay Description:Binding affinity to human MD-2 (17 to 160 residues) assessed as reduction in MD-2 binding to human HMGB1 after 7 mins by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2020
Entry Details Article
PubMed
TargetLymphocyte antigen 96(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50255633(CHEMBL4091601)
Affinity DataKd:  6.70E+4nMAssay Description:Binding to C-terminal His6-tagged human MD2 expressed in Pichia pastoris GS115 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetLymphocyte antigen 96(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50239337(CHEMBL4072822)
Affinity DataIC50: 200nMAssay Description:Binding affinity to CD14/MD2 (unknown origin) expressed in HEK-Blue cells co-expressing TLR4 assessed as inhibition of LPS-induced TLR4 signaling pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2019
Entry Details Article
PubMed
TargetLymphocyte antigen 96(Mouse)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50501804(CHEMBL4517719)
Affinity DataIC50: 530nMAssay Description:Inhibition of MD2-TLR4 protein-protein interaction in ICR mouse peritoneal macrophages assessed as reduction in LPS-induced IL-6 production preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetLymphocyte antigen 96(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50239340(CHEMBL4081306)
Affinity DataIC50: 700nMAssay Description:Binding affinity to CD14/MD2 (unknown origin) expressed in HEK-Blue cells co-expressing TLR4 assessed as inhibition of LPS-induced TLR4 signaling pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2019
Entry Details Article
PubMed
TargetLymphocyte antigen 96/Toll-like receptor 4(Mouse)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50501802(CHEMBL4544533)
Affinity DataIC50: 730nMAssay Description:Inhibition of MD2-TLR4 protein-protein interaction in ICR mouse peritoneal macrophages assessed as reduction in LPS-induced IL-6 production preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetLymphocyte antigen 96(Mouse)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50501803(CHEMBL4458502)
Affinity DataIC50: 840nMAssay Description:Inhibition of MD2-TLR4 protein-protein interaction in ICR mouse peritoneal macrophages assessed as reduction in LPS-induced IL-6 production preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetLymphocyte antigen 96(Mouse)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50501804(CHEMBL4517719)
Affinity DataIC50: 890nMAssay Description:Inhibition of MD2-TLR4 protein-protein interaction in ICR mouse peritoneal macrophages assessed as reduction in LPS-induced TNFalpha production prein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetLymphocyte antigen 96(Mouse)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50501805(CHEMBL4468247)
Affinity DataIC50: 3.47E+3nMAssay Description:Inhibition of MD2-TLR4 protein-protein interaction in ICR mouse peritoneal macrophages assessed as reduction in LPS-induced TNFalpha production prein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetLymphocyte antigen 96(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50277588(CHEMBL4176576)
Affinity DataIC50: 4.22E+3nMAssay Description:Displacement of bis-ANS to recombinant human MD2 after 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2020
Entry Details Article
PubMed
TargetLymphocyte antigen 96(Mouse)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50501805(CHEMBL4468247)
Affinity DataIC50: 4.57E+3nMAssay Description:Inhibition of MD2-TLR4 protein-protein interaction in ICR mouse peritoneal macrophages assessed as reduction in LPS-induced IL-6 production preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetLymphocyte antigen 96(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50239341(CHEMBL4105554)
Affinity DataIC50: 5.70E+3nMAssay Description:Binding affinity to CD14/MD2 (unknown origin) expressed in HEK-Blue cells co-expressing TLR4 assessed as inhibition of LPS-induced TLR4 signaling pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2019
Entry Details Article
PubMed
TargetLymphocyte antigen 96(Mouse)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50501802(CHEMBL4544533)
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of MD2-TLR4 protein-protein interaction in ICR mouse peritoneal macrophages assessed as reduction in LPS-induced TNFalpha production prein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetLymphocyte antigen 96(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50277590(CHEMBL4164940)
Affinity DataIC50: 6.83E+3nMAssay Description:Displacement of bis-ANS to recombinant human MD2 after 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2020
Entry Details Article
PubMed
TargetLymphocyte antigen 96(Mouse)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50501803(CHEMBL4458502)
Affinity DataIC50: 6.99E+3nMAssay Description:Inhibition of MD2-TLR4 protein-protein interaction in ICR mouse peritoneal macrophages assessed as reduction in LPS-induced TNFalpha production prein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetLymphocyte antigen 96(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50277589(CHEMBL4162528)
Affinity DataIC50: 9.08E+3nMAssay Description:Displacement of bis-ANS to recombinant human MD2 after 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2020
Entry Details Article
PubMed
TargetLymphocyte antigen 96(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50239336(CHEMBL4093531)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to CD14/MD2 (unknown origin) expressed in HEK-Blue cells co-expressing TLR4 assessed as inhibition of LPS-induced TLR4 signaling pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2019
Entry Details Article
PubMed
TargetLymphocyte antigen 96(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50239339(CHEMBL4091730)
Affinity DataIC50: 4.50E+4nMAssay Description:Binding affinity to CD14/MD2 (unknown origin) expressed in HEK-Blue cells co-expressing TLR4 assessed as inhibition of LPS-induced TLR4 signaling pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2019
Entry Details Article
PubMed
TargetLymphocyte antigen 96(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50239338(CHEMBL4070859)
Affinity DataIC50: 6.30E+4nMAssay Description:Binding affinity to CD14/MD2 (unknown origin) expressed in HEK-Blue cells co-expressing TLR4 assessed as inhibition of LPS-induced TLR4 signaling pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2019
Entry Details Article
PubMed