Compile Data Set for Download or QSAR
Report error Found 1383 Enz. Inhib. hit(s) with Target = 'Low molecular weight phosphotyrosine protein phosphatase'
LigandPNGBDBM50607111(CHEMBL5218807)
Affinity DataKi:  1.20nMAssay Description:Competitive inhibition of LMW-PTP (unknown origin) assessed as inhibition constant by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50607111(CHEMBL5218807)
Affinity DataIC50: 3nMAssay Description:Inhibition of N-terminal His-tagged full length rat LMW-PTP expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50607111(CHEMBL5218807)
Affinity DataIC50: 3nMAssay Description:Inhibition of N-terminal His-tagged full length mouse LMW-PTP expressed in Escherichia coli BL21(DE3) by SDS PAGE based mass spectrometry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50607111(CHEMBL5218807)
Affinity DataIC50: 4nMAssay Description:Inhibition of His-tagged human LMW-PTP expressed in Escherichia coli BL21 using pNPP as substrate incubated for 10 mins by microplate reader based sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50576941(CHEMBL4875137)
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
LigandPNGBDBM50607137(CHEMBL5219822)
Affinity DataIC50: 8nMAssay Description:Inhibition of His-tagged human LMW-PTP expressed in Escherichia coli BL21 using pNPP as substrate incubated for 10 mins by microplate reader based sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50576927(CHEMBL4856707)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
LigandPNGBDBM50607112(CHEMBL5220114)
Affinity DataIC50: 36nMAssay Description:Inhibition of N-terminal His-tagged full length rat LMW-PTP expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50607112(CHEMBL5220114)
Affinity DataIC50: 36nMAssay Description:Inhibition of N-terminal His-tagged full length mouse LMW-PTP expressed in Escherichia coli BL21(DE3) by SDS PAGE based mass spectrometry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  39nMAssay Description:Binding affinity to human ACP1 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM50607138(CHEMBL5218783)
Affinity DataIC50: 49nMAssay Description:Inhibition of His-tagged human LMW-PTP expressed in Escherichia coli BL21 using pNPP as substrate incubated for 10 mins by microplate reader based sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50607136(CHEMBL5220687)
Affinity DataIC50: 56nMAssay Description:Inhibition of His-tagged human LMW-PTP expressed in Escherichia coli BL21 using pNPP as substrate incubated for 10 mins by microplate reader based sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50607110(CHEMBL5219519)
Affinity DataIC50: 62nMAssay Description:Inhibition of N-terminal His-tagged full length rat LMW-PTP expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50607110(CHEMBL5219519)
Affinity DataIC50: 62nMAssay Description:Inhibition of N-terminal His-tagged full length mouse LMW-PTP expressed in Escherichia coli BL21(DE3) by SDS PAGE based mass spectrometry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50576940(CHEMBL4857535)
Affinity DataIC50: 83nMAssay Description:Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
LigandPNGBDBM50576928(CHEMBL4855952)
Affinity DataIC50: 87nMAssay Description:Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
LigandPNGBDBM50576921(CHEMBL4874911)
Affinity DataIC50: 104nMAssay Description:Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
LigandPNGBDBM50576933(CHEMBL4848127)
Affinity DataIC50: 106nMAssay Description:Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
LigandPNGBDBM50576932(CHEMBL4873827)
Affinity DataIC50: 117nMAssay Description:Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
LigandPNGBDBM50576929(CHEMBL4859307)
Affinity DataIC50: 119nMAssay Description:Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
LigandPNGBDBM50607139(CHEMBL5220615)
Affinity DataIC50: 121nMAssay Description:Inhibition of His-tagged human LMW-PTP expressed in Escherichia coli BL21 using pNPP as substrate incubated for 10 mins by microplate reader based sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50576930(CHEMBL4858034)
Affinity DataIC50: 147nMAssay Description:Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
LigandPNGBDBM50576924(CHEMBL4861843)
Affinity DataIC50: 171nMAssay Description:Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
LigandPNGBDBM50607115(CHEMBL5220051)
Affinity DataIC50: 200nMAssay Description:Inhibition of His-tagged human LMW-PTP expressed in Escherichia coli BL21 using pNPP as substrate incubated for 10 mins by microplate reader based sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 200nMAssay Description:Inhibition of N-terminal His-tagged full length mouse LMW-PTP expressed in Escherichia coli BL21(DE3) by SDS PAGE based mass spectrometry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50341993(4-((3-((3-(4-carboxybenzyl)-4-oxo-2-(phenylimino)t...)
Affinity DataIC50: 220nMAssay Description:Inhibition of human LMW-PTPase isoform 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50576931(CHEMBL4870698)
Affinity DataIC50: 239nMAssay Description:Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
LigandPNGBDBM50576919(CHEMBL4847980)
Affinity DataIC50: 239nMAssay Description:Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
LigandPNGBDBM50576934(CHEMBL4868378)
Affinity DataIC50: 245nMAssay Description:Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
LigandPNGBDBM50256796(6,7-Dihydroxy-2-(4'-hydroxyphenyl)-3-[(1,1'-biphen...)
Affinity DataKi:  270nMAssay Description:Inhibition of human cloned LMW-PTP isoform 1 expressed in Escherichia coli TB1 by competitive inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50576926(CHEMBL4857590)
Affinity DataIC50: 288nMAssay Description:Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
LigandPNGBDBM50607120(CHEMBL5218478)
Affinity DataIC50: 300nMAssay Description:Inhibition of His-tagged human LMW-PTP expressed in Escherichia coli BL21 using pNPP as substrate incubated for 10 mins by microplate reader based sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50607121(CHEMBL5219403)
Affinity DataIC50: 300nMAssay Description:Inhibition of His-tagged human LMW-PTP expressed in Escherichia coli BL21 using pNPP as substrate incubated for 10 mins by microplate reader based sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 300nMAssay Description:Inhibition of N-terminal His-tagged full length rat LMW-PTP expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50576920(CHEMBL4852414)
Affinity DataIC50: 306nMAssay Description:Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
LigandPNGBDBM50256796(6,7-Dihydroxy-2-(4'-hydroxyphenyl)-3-[(1,1'-biphen...)
Affinity DataKi:  340nMAssay Description:Inhibition of human cloned LMW-PTP isoform 2 expressed in Escherichia coli TB1 by competitive inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50436358(CHEMBL2396718)
Affinity DataIC50: 340nMAssay Description:Inhibition of recombinant LMWPTP (unknown origin) using pNPP as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50576925(CHEMBL4846731)
Affinity DataIC50: 380nMAssay Description:Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
LigandPNGBDBM50607118(CHEMBL5219065)
Affinity DataIC50: 400nMAssay Description:Inhibition of His-tagged human LMW-PTP expressed in Escherichia coli BL21 using pNPP as substrate incubated for 10 mins by microplate reader based sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50607117(CHEMBL5218609)
Affinity DataIC50: 400nMAssay Description:Inhibition of His-tagged human LMW-PTP expressed in Escherichia coli BL21 using pNPP as substrate incubated for 10 mins by microplate reader based sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM533137(US11220486, Compound I67 | N-(3-hydroxypropyl)(4-{...)
Affinity DataIC50: 500nMAssay Description:A listing of materials is provided: Item, source, catalog no. LMPTP-A Enzyme Stock Solution (4.22 mg/ml or 206.8 μM), SBMRI Protei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
Go to US Patent

LigandPNGBDBM533265(US11220486, Compound I195 | N-(3-aminopropyl)(4-{4...)
Affinity DataIC50: 500nMAssay Description:A listing of materials is provided: Item, source, catalog no. LMPTP-A Enzyme Stock Solution (4.22 mg/ml or 206.8 μM), SBMRI Protei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
Go to US Patent

LigandPNGBDBM533136(US11220486, Compound I66 | N-[2-(dimethylamino)eth...)
Affinity DataIC50: 500nMAssay Description:A listing of materials is provided: Item, source, catalog no. LMPTP-A Enzyme Stock Solution (4.22 mg/ml or 206.8 μM), SBMRI Protei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
Go to US Patent

LigandPNGBDBM533267(US11220486, Compound I197 | N-(4-piperidylmethyl)(...)
Affinity DataIC50: 500nMAssay Description:A listing of materials is provided: Item, source, catalog no. LMPTP-A Enzyme Stock Solution (4.22 mg/ml or 206.8 μM), SBMRI Protei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
Go to US Patent

LigandPNGBDBM533266(US11220486, Compound I196 | N-(4-piperidyl)(4-{4-[...)
Affinity DataIC50: 500nMAssay Description:A listing of materials is provided: Item, source, catalog no. LMPTP-A Enzyme Stock Solution (4.22 mg/ml or 206.8 μM), SBMRI Protei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
Go to US Patent

LigandPNGBDBM533141(US11220486, Compound I71 | N,N-diethyl(4-{4-[(3-pi...)
Affinity DataIC50: 500nMAssay Description:A listing of materials is provided: Item, source, catalog no. LMPTP-A Enzyme Stock Solution (4.22 mg/ml or 206.8 μM), SBMRI Protei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
Go to US Patent

LigandPNGBDBM533268(US11220486, Compound I198 | N-(3-piperidylpropyl)(...)
Affinity DataIC50: 500nMAssay Description:A listing of materials is provided: Item, source, catalog no. LMPTP-A Enzyme Stock Solution (4.22 mg/ml or 206.8 μM), SBMRI Protei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
Go to US Patent

LigandPNGBDBM533144(US11220486, Compound I74 | 4-{4-[(3-piperidylpropy...)
Affinity DataIC50: 500nMAssay Description:A listing of materials is provided: Item, source, catalog no. LMPTP-A Enzyme Stock Solution (4.22 mg/ml or 206.8 μM), SBMRI Protei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
Go to US Patent

LigandPNGBDBM533021(US11220486, Compound G38 | 3-[2-(4-Methoxy-phenyl)...)
Affinity DataIC50: 500nMAssay Description:A listing of materials is provided: Item, source, catalog no. LMPTP-A Enzyme Stock Solution (4.22 mg/ml or 206.8 μM), SBMRI Protei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
Go to US Patent

LigandPNGBDBM533148(US11220486, Compound I257 | (2-benzo[b]thiophen-6-...)
Affinity DataIC50: 500nMAssay Description:A listing of materials is provided: Item, source, catalog no. LMPTP-A Enzyme Stock Solution (4.22 mg/ml or 206.8 μM), SBMRI Protei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
Go to US Patent

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