Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) with Target = 'Lanosterol 14-alpha demethylase [F78L]'
TargetLanosterol 14-alpha demethylase [F78L](Mycobacterium tuberculosis)
University of California San Francisco

LigandPNGBDBM25810(JMC522846 Compound 5 | 2-phenyl-N-(pyridin-4-yl)bu...)
Affinity DataKd:  1.95E+4nMpH: 7.5 T: 2°CAssay Description:The assay was developed based on the optical spectral property of P450 enzyme to elicit both type I and type II spectral changes (350 nm through 450 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetLanosterol 14-alpha demethylase [F78L](Mycobacterium tuberculosis)
University of California San Francisco

LigandPNGBDBM25816(2-(2,1,3-benzothiadiazole-4-sulfonamido)-2-phenyl-...)
Affinity DataKd:  2.32E+4nMpH: 7.5 T: 2°CAssay Description:The assay was developed based on the optical spectral property of P450 enzyme to elicit both type I and type II spectral changes (350 nm through 450 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)