Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with Target = 'Kynureninase'
TargetKynureninase(Rat)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50069732(2-Amino-3-(2-amino-5-methyl-benzenesulfonyl)-propi...)
Affinity DataIC50: 1.10E+4nMAssay Description:Compound was tested for the inhibition of mammalian kynureninase in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKynureninase(Rat)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50069731(2-Amino-3-(2-amino-3-fluoro-benzenesulfonyl)-propi...)
Affinity DataIC50: 2.00E+4nMAssay Description:Compound was tested for the inhibition of mammalian kynureninase in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKynureninase(Rat)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50069729(2-Amino-3-(2-amino-3-methoxy-benzenesulfonyl)-prop...)
Affinity DataIC50: 2.90E+4nMAssay Description:Compound was tested for the inhibition of mammalian kynureninase in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKynureninase(Rat)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50069730(2-Amino-3-(2-amino-benzenesulfonyl)-propionic acid...)
Affinity DataIC50: 3.60E+4nMAssay Description:Compound was tested for the inhibition of mammalian kynureninase in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKynureninase(Rat)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50083950((S)-2-Amino-4-(3-nitro-phenyl)-4-oxo-butyric acid ...)
Affinity DataIC50: 6.00E+4nMAssay Description:Tested for inhibitory activity against kynureninase from rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetKynureninase(Rat)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50284766((R)-2-Amino-4-(3-nitro-phenyl)-4-oxo-butyric acid ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Tested for inhibitory activity against kynureninase from rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetKynureninase(Rat)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50061907(meta-nitrobenzoyl)alanine | 2-Amino-4-(3-nitro-phe...)
Affinity DataIC50: 1.00E+5nMAssay Description:Ability to inhibit kynureninase was determined in a competitive inhibition assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetKynureninase(Rat)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50040567(ortho-nitrobenzoyl)alanine | CHEMBL158499)
Affinity DataIC50: 1.00E+5nMAssay Description:Ability to inhibit kynureninase was determined in a competitive inhibition assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetKynureninase(Rat)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50040570(CHEMBL160527 | nicotinoylalanine(NAL) | NICOTINOYL...)
Affinity DataIC50: 8.00E+5nMAssay Description:Ability to inhibit kynureninase was determined in a competitive inhibition assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetKynureninase(Rat)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50040568(para-nitrobenzoyl)alanine | CHEMBL157866)
Affinity DataIC50: 9.00E+5nMAssay Description:Ability to inhibit kynureninase was determined in a competitive inhibition assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetKynureninase(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50069730(2-Amino-3-(2-amino-benzenesulfonyl)-propionic acid...)
Affinity DataKi:  70nMAssay Description:Compound was tested for the binding affinity against bacterial kynureninaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKynureninase(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50288256((R)-2-Amino-3-(2-amino-benzenesulfonyl)-propionic ...)
Affinity DataKi:  70nMAssay Description:Compound was evaluated for its binding affinity against kynureninase isolated from Pseudomonas fluorescenceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetKynureninase(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50109155(2-amino-4-[3'-hydroxyphenyl]-4-hydroxybutanoic aci...)
Affinity DataKi:  100nMAssay Description:Binding affinity to human recombinant Kynureninase assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetKynureninase(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50109155(2-amino-4-[3'-hydroxyphenyl]-4-hydroxybutanoic aci...)
Affinity DataKi:  100nMAssay Description:Tested for binding affinity against kynureninase enzyme from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKynureninase(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50109155(2-amino-4-[3'-hydroxyphenyl]-4-hydroxybutanoic aci...)
Affinity DataKi:  100nMAssay Description:Inhibition of human kynureninaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKynureninase(Rat)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50109155(2-amino-4-[3'-hydroxyphenyl]-4-hydroxybutanoic aci...)
Affinity DataKi:  130nMAssay Description:Binding affinity to rat Kynureninase assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetKynureninase(Rat)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50109155(2-amino-4-[3'-hydroxyphenyl]-4-hydroxybutanoic aci...)
Affinity DataKi:  130nMAssay Description:Tested for binding affinity against kynureninase enzyme from ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKynureninase(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50288255(2-ammonio-4-(2-ammoniophenyl)-4-oxo-(2S)-butanoate)
Affinity DataKi:  4.28E+3nMAssay Description:Compound was evaluated for its binding affinity against kynureninase isolated from Pseudomonas fluorescenceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetKynureninase(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50288257((R)-2-Benzyloxycarbonylamino-3-(methoxy-phenyl-pho...)
Affinity DataKi:  8.80E+3nMAssay Description:Compound was evaluated for its binding affinity against kynureninase isolated from Pseudomonas fluorescenceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetKynureninase(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50109155(2-amino-4-[3'-hydroxyphenyl]-4-hydroxybutanoic aci...)
Affinity DataKi:  1.00E+4nMAssay Description:Tested for binding affinity against kynureninase enzyme from bacterial cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKynureninase(Rat)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50069730(2-Amino-3-(2-amino-benzenesulfonyl)-propionic acid...)
Affinity DataKi:  1.80E+4nMAssay Description:Compound was tested for the binding affinity against kynureninase in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKynureninase(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50288254(2-ammonio-4-oxo-4-phenyl-(2S)-butanoate | CHEMBL31...)
Affinity DataKi:  2.34E+4nMAssay Description:Compound was evaluated for its binding affinity against kynureninase isolated from Pseudomonas fluorescenceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetKynureninase(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50265459(3-Hydroxyhippuric acid | CHEMBL447627)
Affinity DataKi:  6.00E+4nMAssay Description:Inhibition of human kynureninaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetKynureninase(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50288258((R)-2-Benzyloxycarbonylamino-3-(methoxy-phenyl-pho...)
Affinity DataKi:  8.80E+5nMAssay Description:Compound was evaluated for its binding affinity against kynureninase isolated from Pseudomonas fluorescenceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article