Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with Target = 'Kinesin-like protein KIF15'
TargetKinesin-like protein KIF15(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50518447(CHEMBL4540278)
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant His6-tagged Kif15 (N700 residues) (unknown origin) expressed in HeLa cells assessed as reduction in Alexa-594 labelled micr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetKinesin-like protein KIF15(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50085411(3-[1-(3,5-Dichloro-4-hydroxy-phenyl)-meth-(Z)-ylid...)
Affinity DataIC50: 750nMAssay Description:Inhibition of recombinant His6-tagged Kif15 (N700 residues) (unknown origin) expressed in HeLa cells assessed as reduction in Alexa-594 labelled micr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetKinesin-like protein KIF15(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50085411(3-[1-(3,5-Dichloro-4-hydroxy-phenyl)-meth-(Z)-ylid...)
Affinity DataIC50: 820nMAssay Description:Inhibition of recombinant His6-tagged Kif15 ATPase activity (N420 residues) (unknown origin) expressed in HeLa cells using microtubule as substrate p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetKinesin-like protein KIF15/Targeting protein for Xklp2(Human)
University of Kansas

US Patent
LigandPNGBDBM700780(6-(2-chlorobenzyl)-2-(4-ethylpiperazin-1-yl)-5,6,7...)
Affinity DataIC50: 1.50E+3nMAssay Description:An AlphaScreen-based high-throughput screening assay can be used to identify inhibitors of the KIF15-TPX2 protein-protein interaction. These inhibito...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
Go to US Patent

TargetKinesin-like protein KIF15/Targeting protein for Xklp2(Human)
University of Kansas

US Patent
LigandPNGBDBM700779(2-(4-ethylpiperazin-1-yl)-6-(2,3,4-trimethoxybenzy...)
Affinity DataIC50: 1.70E+3nMAssay Description:An AlphaScreen-based high-throughput screening assay can be used to identify inhibitors of the KIF15-TPX2 protein-protein interaction. These inhibito...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
Go to US Patent

TargetKinesin-like protein KIF15(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50518447(CHEMBL4540278)
Affinity DataIC50: 1.72E+3nMAssay Description:Inhibition of recombinant C-terminal truncated His6-tagged Kif15 (N700 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetKinesin-like protein KIF15/Targeting protein for Xklp2(Human)
University of Kansas

US Patent
LigandPNGBDBM700778(2-(4-ethylpiperazin-1-yl)-6-(2,4,5-trimethoxybenzy...)
Affinity DataIC50: 2.40E+3nMAssay Description:An AlphaScreen-based high-throughput screening assay can be used to identify inhibitors of the KIF15-TPX2 protein-protein interaction. These inhibito...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
Go to US Patent

TargetKinesin-like protein KIF15(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50085415(G6416 (GW5074) | 3-(3,5-dibromo-4-hydroxybenzylide...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of recombinant His6-tagged Kif15 ATPase activity (N420 residues) (unknown origin) expressed in HeLa cells using microtubule as substrate p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetKinesin-like protein KIF15/Targeting protein for Xklp2(Human)
University of Kansas

US Patent
LigandPNGBDBM700781(2-(4-ethylpiperazin-1-yl)-6-(3,4,5-trimethoxybenzy...)
Affinity DataIC50: 2.50E+3nMAssay Description:An AlphaScreen-based high-throughput screening assay can be used to identify inhibitors of the KIF15-TPX2 protein-protein interaction. These inhibito...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
Go to US Patent

TargetKinesin-like protein KIF15/Targeting protein for Xklp2(Human)
University of Kansas

US Patent
LigandPNGBDBM700777(6-(3,4-diethoxybenzyl)-2-(4-ethylpiperazin-1-yl)-5...)
Affinity DataIC50: 2.80E+3nMAssay Description:An AlphaScreen-based high-throughput screening assay can be used to identify inhibitors of the KIF15-TPX2 protein-protein interaction. These inhibito...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
Go to US Patent

TargetKinesin-like protein KIF15/Targeting protein for Xklp2(Human)
University of Kansas

US Patent
LigandPNGBDBM700782(6-(4-ethoxy-3-methoxybenzyl)-2-(4-ethylpiperazin-1...)
Affinity DataIC50: 3.50E+3nMAssay Description:An AlphaScreen-based high-throughput screening assay can be used to identify inhibitors of the KIF15-TPX2 protein-protein interaction. These inhibito...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
Go to US Patent

TargetKinesin-like protein KIF15/Targeting protein for Xklp2(Human)
University of Kansas

US Patent
LigandPNGBDBM700784(4-allyl-2-methyl-N-(pyridin-2-ylmethyl)-4H-thieno[...)
Affinity DataIC50: 5.60E+3nMAssay Description:An AlphaScreen-based high-throughput screening assay can be used to identify inhibitors of the KIF15-TPX2 protein-protein interaction. These inhibito...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
Go to US Patent

TargetKinesin-like protein KIF15/Targeting protein for Xklp2(Human)
University of Kansas

US Patent
LigandPNGBDBM700776(6-(4-bromobenzyl)-2-(4-propylpiperazin-1-yl)-5,6,7...)
Affinity DataIC50: 1.36E+4nMAssay Description:An AlphaScreen-based high-throughput screening assay can be used to identify inhibitors of the KIF15-TPX2 protein-protein interaction. These inhibito...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
Go to US Patent

TargetKinesin-like protein KIF15/Targeting protein for Xklp2(Human)
University of Kansas

US Patent
LigandPNGBDBM700775(6-(3-bromobenzyl)-2-(4-propylpiperazin-1-yl)-5,6,7...)
Affinity DataIC50: 2.10E+4nMAssay Description:An AlphaScreen-based high-throughput screening assay can be used to identify inhibitors of the KIF15-TPX2 protein-protein interaction. These inhibito...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
Go to US Patent

TargetKinesin-like protein KIF15/Targeting protein for Xklp2(Human)
University of Kansas

US Patent
LigandPNGBDBM700774(6-((5-bromothiophen-2-yl)methyl)-2-(4-propylpipera...)
Affinity DataIC50: 2.30E+4nMAssay Description:An AlphaScreen-based high-throughput screening assay can be used to identify inhibitors of the KIF15-TPX2 protein-protein interaction. These inhibito...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
Go to US Patent

TargetKinesin-like protein KIF15/Targeting protein for Xklp2(Human)
University of Kansas

US Patent
LigandPNGBDBM700772(6-(2,3-difluorobenzyl)-2-(4-propylpiperazin-1-yl)-...)
Affinity DataIC50: 2.78E+4nMAssay Description:An AlphaScreen-based high-throughput screening assay can be used to identify inhibitors of the KIF15-TPX2 protein-protein interaction. These inhibito...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
Go to US Patent

TargetKinesin-like protein KIF15/Targeting protein for Xklp2(Human)
University of Kansas

US Patent
LigandPNGBDBM700771(6-(4-ethylbenzyl)-2-(4-propylpiperazin-1-yl)-5,6,7...)
Affinity DataIC50: 3.22E+4nMAssay Description:An AlphaScreen-based high-throughput screening assay can be used to identify inhibitors of the KIF15-TPX2 protein-protein interaction. These inhibito...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
Go to US Patent

TargetKinesin-like protein KIF15/Targeting protein for Xklp2(Human)
University of Kansas

US Patent
LigandPNGBDBM700773(6-(3,4-diethoxybenzyl)-2-(4-propylpiperazin-1-yl)-...)
Affinity DataIC50: 4.22E+4nMAssay Description:An AlphaScreen-based high-throughput screening assay can be used to identify inhibitors of the KIF15-TPX2 protein-protein interaction. These inhibito...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
Go to US Patent

TargetKinesin-like protein KIF15/Targeting protein for Xklp2(Human)
University of Kansas

US Patent
LigandPNGBDBM700783(6-(4-ethoxy-3-methoxybenzyl)-2-(4-propylpiperazin-...)
Affinity DataIC50: 4.48E+4nMAssay Description:An AlphaScreen-based high-throughput screening assay can be used to identify inhibitors of the KIF15-TPX2 protein-protein interaction. These inhibito...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
Go to US Patent