Compile Data Set for Download or QSAR
Report error Found 771 Enz. Inhib. hit(s) with Target = 'Isoform PDE10A2 of cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (PDE10A2)'
LigandPNGBDBM701094((3aS,6aR)-5-[1-methyl-6-[2- (4-phenyl-1H-imidazol-...)
Affinity DataIC50: 0.0250nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
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LigandPNGBDBM701102(US20240343729, Example 17)
Affinity DataIC50: 0.0320nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
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LigandPNGBDBM701095(2-[3-[2-[2-[4-[(3aS,6aR)- 1,3,3a,4,6,6a- Hexahydro...)
Affinity DataIC50: 0.0400nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
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LigandPNGBDBM701097((3R)-3-Methyl-4-[2-[2-(1- methyl-4-phenyl-imidazol...)
Affinity DataIC50: 0.0400nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
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LigandPNGBDBM701108(US20240343729, Example 23)
Affinity DataIC50: 0.0400nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
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LigandPNGBDBM701106(US20240343729, Example 21)
Affinity DataIC50: 0.0500nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
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LigandPNGBDBM252902(US9464076, 54)
Affinity DataIC50: 0.0540nMpH: 7.5 T: 2°CAssay Description:A human acute lymphoblastic lymphoma T cell line MOLT-4 (which can be purchased under ATCC No. CRL-1582 from ATCC) was cultured in an RPMI1640 medium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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LigandPNGBDBM701101(US20240343729, Example 16)
Affinity DataIC50: 0.0790nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
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LigandPNGBDBM701109(US20240343729, Example 24)
Affinity DataIC50: 0.0790nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
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LigandPNGBDBM701119(US20240343729, Reference Example A)
Affinity DataIC50: 0.0790nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2025
Entry Details
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LigandPNGBDBM700244(2-[[4-[1-Methyl-4-(4-pyridyl)pyrazol-3-yl]phenoxy]...)
Affinity DataIC50: 0.0790nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2025
Entry Details
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LigandPNGBDBM700249(N-[Dimethyl(oxo)- lambda6-sulfanylidene]-2- [[4-[1...)
Affinity DataIC50: 0.0790nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2025
Entry Details
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LigandPNGBDBM252906(US9464076, 58)
Affinity DataIC50: 0.0850nMpH: 7.5 T: 2°CAssay Description:A human acute lymphoblastic lymphoma T cell line MOLT-4 (which can be purchased under ATCC No. CRL-1582 from ATCC) was cultured in an RPMI1640 medium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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LigandPNGBDBM700248(N-[Dimethyl(oxo)- lambda6-sulfanylidene]-2- [4-[1-...)
Affinity DataIC50: 0.100nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2025
Entry Details
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LigandPNGBDBM701088(US20240343729, Example 3)
Affinity DataIC50: 0.102nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
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LigandPNGBDBM701103(US20240343729, Example 18)
Affinity DataIC50: 0.102nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
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LigandPNGBDBM701111((3aR,6aS)-5-(1- (Cyclopropylmethyl)-6-((4- phenyl-...)
Affinity DataIC50: 0.102nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
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LigandPNGBDBM252941(US9464076, 93)
Affinity DataIC50: 0.110nMpH: 7.5 T: 2°CAssay Description:A human acute lymphoblastic lymphoma T cell line MOLT-4 (which can be purchased under ATCC No. CRL-1582 from ATCC) was cultured in an RPMI1640 medium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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LigandPNGBDBM252947(US9464076, 99)
Affinity DataIC50: 0.110nMpH: 7.5 T: 2°CAssay Description:A human acute lymphoblastic lymphoma T cell line MOLT-4 (which can be purchased under ATCC No. CRL-1582 from ATCC) was cultured in an RPMI1640 medium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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LigandPNGBDBM252949(US9464076, 101)
Affinity DataIC50: 0.110nMpH: 7.5 T: 2°CAssay Description:A human acute lymphoblastic lymphoma T cell line MOLT-4 (which can be purchased under ATCC No. CRL-1582 from ATCC) was cultured in an RPMI1640 medium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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LigandPNGBDBM701110((3aR,6aS)-5-(1-isopPropyl- 6-((4-phenyl-1H-imidazo...)
Affinity DataIC50: 0.112nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
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LigandPNGBDBM252961(US9464076, 113)
Affinity DataIC50: 0.120nMpH: 7.5 T: 2°CAssay Description:A human acute lymphoblastic lymphoma T cell line MOLT-4 (which can be purchased under ATCC No. CRL-1582 from ATCC) was cultured in an RPMI1640 medium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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LigandPNGBDBM701114((R)-3-Methyl-4-(9-methyl-2- ((4-phenyl-1H-imidazol...)
Affinity DataIC50: 0.120nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
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LigandPNGBDBM700257(N-[Dimethyl(oxo)-λ6-sulfanylidene]-2-[[4-[1-m...)
Affinity DataIC50: 0.120nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2025
Entry Details
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LigandPNGBDBM701117((R)-3-Methyl-4-(9-methyl-2- ((4-(pyridin-3-yl)-1H-...)
Affinity DataIC50: 0.126nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
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LigandPNGBDBM252887(US9464076, 39 | US9464076, 40 | US9464076, 41 | US...)
Affinity DataIC50: 0.150nMpH: 7.5 T: 2°CAssay Description:A human acute lymphoblastic lymphoma T cell line MOLT-4 (which can be purchased under ATCC No. CRL-1582 from ATCC) was cultured in an RPMI1640 medium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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LigandPNGBDBM701096(4-[2-[2-(1-Methyl-4-phenyl- imidazol-2-yl)ethynyl]...)
Affinity DataIC50: 0.158nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
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LigandPNGBDBM700263(N-[Dimethyl(oxo)- lambda6-sulfanylidene]-2- [[4-[1...)
Affinity DataIC50: 0.174nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2025
Entry Details
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LigandPNGBDBM252946(US9464076, 98)
Affinity DataIC50: 0.210nMpH: 7.5 T: 2°CAssay Description:A human acute lymphoblastic lymphoma T cell line MOLT-4 (which can be purchased under ATCC No. CRL-1582 from ATCC) was cultured in an RPMI1640 medium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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LigandPNGBDBM252950(US9464076, 102 | US9464076, 122 | US9464076, 121 |...)
Affinity DataIC50: 0.220nMpH: 7.5 T: 2°CAssay Description:A human acute lymphoblastic lymphoma T cell line MOLT-4 (which can be purchased under ATCC No. CRL-1582 from ATCC) was cultured in an RPMI1640 medium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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LigandPNGBDBM252886(US9464076, 38)
Affinity DataIC50: 0.230nMpH: 7.5 T: 2°CAssay Description:A human acute lymphoblastic lymphoma T cell line MOLT-4 (which can be purchased under ATCC No. CRL-1582 from ATCC) was cultured in an RPMI1640 medium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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LigandPNGBDBM252957(US9464076, 109 | US9464076, 111 | US9464076, 110 |...)
Affinity DataIC50: 0.230nMpH: 7.5 T: 2°CAssay Description:A human acute lymphoblastic lymphoma T cell line MOLT-4 (which can be purchased under ATCC No. CRL-1582 from ATCC) was cultured in an RPMI1640 medium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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LigandPNGBDBM252945(US9464076, 97)
Affinity DataIC50: 0.260nMpH: 7.5 T: 2°CAssay Description:A human acute lymphoblastic lymphoma T cell line MOLT-4 (which can be purchased under ATCC No. CRL-1582 from ATCC) was cultured in an RPMI1640 medium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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LigandPNGBDBM252883(US9464076, 35)
Affinity DataIC50: 0.290nMpH: 7.5 T: 2°CAssay Description:A human acute lymphoblastic lymphoma T cell line MOLT-4 (which can be purchased under ATCC No. CRL-1582 from ATCC) was cultured in an RPMI1640 medium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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LigandPNGBDBM252950(US9464076, 102 | US9464076, 122 | US9464076, 121 |...)
Affinity DataIC50: 0.290nMpH: 7.5 T: 2°CAssay Description:A human acute lymphoblastic lymphoma T cell line MOLT-4 (which can be purchased under ATCC No. CRL-1582 from ATCC) was cultured in an RPMI1640 medium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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LigandPNGBDBM701105(US20240343729, Example 20)
Affinity DataIC50: 0.295nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
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LigandPNGBDBM252950(US9464076, 102 | US9464076, 122 | US9464076, 121 |...)
Affinity DataIC50: 0.300nMpH: 7.5 T: 2°CAssay Description:A human acute lymphoblastic lymphoma T cell line MOLT-4 (which can be purchased under ATCC No. CRL-1582 from ATCC) was cultured in an RPMI1640 medium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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LigandPNGBDBM252950(US9464076, 102 | US9464076, 122 | US9464076, 121 |...)
Affinity DataIC50: 0.310nMpH: 7.5Assay Description:Inhibitory activity-1 assay: To a solution containing 20 mM Tris-HCl (pH 7.5), 1 mM MgCl2, 100 μM EDTA, 330 μg/ml bovine serum albumin, 50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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LigandPNGBDBM252907(US9464076, 59)
Affinity DataIC50: 0.310nMpH: 7.5 T: 2°CAssay Description:A human acute lymphoblastic lymphoma T cell line MOLT-4 (which can be purchased under ATCC No. CRL-1582 from ATCC) was cultured in an RPMI1640 medium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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LigandPNGBDBM252944(US9464076, 96)
Affinity DataIC50: 0.310nMpH: 7.5 T: 2°CAssay Description:A human acute lymphoblastic lymphoma T cell line MOLT-4 (which can be purchased under ATCC No. CRL-1582 from ATCC) was cultured in an RPMI1640 medium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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LigandPNGBDBM701112((3aR,6aS)-5-(1-(Oxetan-3- yl)-6-((4-phenyl-1H- imi...)
Affinity DataIC50: 0.324nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
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LigandPNGBDBM252925(US9464076, 77 | US9464076, 80 | US9464076, 81 | US...)
Affinity DataIC50: 0.340nMpH: 7.5 T: 2°CAssay Description:A human acute lymphoblastic lymphoma T cell line MOLT-4 (which can be purchased under ATCC No. CRL-1582 from ATCC) was cultured in an RPMI1640 medium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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LigandPNGBDBM252884(US9464076, 36)
Affinity DataIC50: 0.350nMpH: 7.5 T: 2°CAssay Description:A human acute lymphoblastic lymphoma T cell line MOLT-4 (which can be purchased under ATCC No. CRL-1582 from ATCC) was cultured in an RPMI1640 medium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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LigandPNGBDBM252887(US9464076, 39 | US9464076, 40 | US9464076, 41 | US...)
Affinity DataIC50: 0.350nMpH: 7.5 T: 2°CAssay Description:A human acute lymphoblastic lymphoma T cell line MOLT-4 (which can be purchased under ATCC No. CRL-1582 from ATCC) was cultured in an RPMI1640 medium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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LigandPNGBDBM252937(US9464076, 89)
Affinity DataIC50: 0.370nMpH: 7.5 T: 2°CAssay Description:A human acute lymphoblastic lymphoma T cell line MOLT-4 (which can be purchased under ATCC No. CRL-1582 from ATCC) was cultured in an RPMI1640 medium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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LigandPNGBDBM700261(N-[Dimethyl(oxo)- lambda6-sulfanylidene]-2- [[4-[1...)
Affinity DataIC50: 0.372nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2025
Entry Details
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LigandPNGBDBM252915(US9464076, 67 | US9464076, 118 | US9464076, 68 | U...)
Affinity DataIC50: 0.380nMpH: 7.5 T: 2°CAssay Description:A human acute lymphoblastic lymphoma T cell line MOLT-4 (which can be purchased under ATCC No. CRL-1582 from ATCC) was cultured in an RPMI1640 medium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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LigandPNGBDBM701104(US20240343729, Example 19)
Affinity DataIC50: 0.389nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
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LigandPNGBDBM252913(US9464076, 65)
Affinity DataIC50: 0.390nMpH: 7.5 T: 2°CAssay Description:A human acute lymphoblastic lymphoma T cell line MOLT-4 (which can be purchased under ATCC No. CRL-1582 from ATCC) was cultured in an RPMI1640 medium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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LigandPNGBDBM252887(US9464076, 39 | US9464076, 40 | US9464076, 41 | US...)
Affinity DataIC50: 0.410nMpH: 7.5Assay Description:Inhibitory activity-1 assay: To a solution containing 20 mM Tris-HCl (pH 7.5), 1 mM MgCl2, 100 μM EDTA, 330 μg/ml bovine serum albumin, 50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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