Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with Target = 'Interleukin-6 receptor subunit beta'
TargetInterleukin-6 receptor subunit beta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50552020(CHEMBL4777424)
Affinity DataKd:  3.80E+3nMAssay Description:Binding affinity to immobilized GP130 (unknown origin) by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetInterleukin-6 receptor subunit beta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50552019(CHEMBL4740172)
Affinity DataKd:  1.43E+5nMAssay Description:Binding affinity to immobilized GP130 (unknown origin) by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetInterleukin-6 receptor subunit beta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50496302(MADINDOLINE A)
Affinity DataKd:  2.88E+5nMAssay Description:Binding affinity to GP130 (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetInterleukin-6 receptor subunit beta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50145177(CHEMBL3764956)
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition of gp130-IL6/IL-Ralpha interaction in human HepG2 cells assessed as inhibition of IL-6-induced STAT3 activation by luciferase reporter gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2017
Entry Details Article
PubMed
TargetInterleukin-6 receptor subunit beta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50145193(CHEMBL3765505)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of gp130-IL6/IL-Ralpha interaction in human HepG2 cells assessed as inhibition of IL-6-induced STAT3 activation by luciferase reporter gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2017
Entry Details Article
PubMed
TargetInterleukin-6 receptor subunit beta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50145178(CHEMBL3764721)
Affinity DataIC50: 6.38E+3nMAssay Description:Inhibition of gp130-IL6/IL-Ralpha interaction in human HepG2 cells assessed as inhibition of IL-6-induced STAT3 activation by luciferase reporter gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2017
Entry Details Article
PubMed
TargetInterleukin-6 receptor subunit beta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50145189(CHEMBL3764217)
Affinity DataIC50: 6.55E+3nMAssay Description:Inhibition of gp130-IL6/IL-Ralpha interaction in human HepG2 cells assessed as inhibition of IL-6-induced STAT3 activation by luciferase reporter gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2017
Entry Details Article
PubMed
TargetInterleukin-6 receptor subunit beta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50145194(CHEMBL3765178)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of gp130-IL6/IL-Ralpha interaction in human HepG2 cells assessed as inhibition of IL-6-induced STAT3 activation by luciferase reporter gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2017
Entry Details Article
PubMed
TargetInterleukin-6 receptor subunit beta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50145192(CHEMBL3765653)
Affinity DataIC50: 9.33E+3nMAssay Description:Inhibition of gp130-IL6/IL-Ralpha interaction in human HepG2 cells assessed as inhibition of IL-6-induced STAT3 activation by luciferase reporter gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2017
Entry Details Article
PubMed
TargetInterleukin-6 receptor subunit beta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50145180(CHEMBL3763273)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of gp130-IL6/IL-Ralpha interaction in human HepG2 cells assessed as inhibition of IL-6-induced STAT3 activation by luciferase reporter gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2017
Entry Details Article
PubMed
TargetInterleukin-6 receptor subunit beta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50145184(CHEMBL3764562)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of gp130-IL6/IL-Ralpha interaction in human HepG2 cells assessed as inhibition of IL-6-induced STAT3 activation by luciferase reporter gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2017
Entry Details Article
PubMed
TargetInterleukin-6 receptor subunit beta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50145187(CHEMBL3763533)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of gp130-IL6/IL-Ralpha interaction in human HepG2 cells assessed as inhibition of IL-6-induced STAT3 activation by luciferase reporter gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2017
Entry Details Article
PubMed
TargetInterleukin-6 receptor subunit beta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50145181(CHEMBL3765814)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of gp130-IL6/IL-Ralpha interaction in human HepG2 cells assessed as inhibition of IL-6-induced STAT3 activation by luciferase reporter gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2017
Entry Details Article
PubMed
TargetInterleukin-6 receptor subunit beta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50145179(CHEMBL3764020)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of gp130-IL6/IL-Ralpha interaction in human HepG2 cells assessed as inhibition of IL-6-induced STAT3 activation by luciferase reporter gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2017
Entry Details Article
PubMed
TargetInterleukin-6 receptor subunit beta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50145195(CHEMBL3765143)
Affinity DataIC50: 2.01E+4nMAssay Description:Inhibition of gp130-IL6/IL-Ralpha interaction in human HepG2 cells assessed as inhibition of IL-6-induced STAT3 activation by luciferase reporter gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2017
Entry Details Article
PubMed
TargetInterleukin-6 receptor subunit beta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50145176((+)-Madindoline A | CHEMBL382330)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of gp130-IL6/IL-Ralpha interaction in human HepG2 cells assessed as inhibition of IL-6-induced STAT3 activation by luciferase reporter gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2017
Entry Details Article
PubMed
TargetInterleukin-6 receptor subunit beta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50145190(CHEMBL3763626)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of gp130-IL6/IL-Ralpha interaction in human HepG2 cells assessed as inhibition of IL-6-induced STAT3 activation by luciferase reporter gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2017
Entry Details Article
PubMed
TargetInterleukin-6 receptor subunit beta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50145196(CHEMBL3765446)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of gp130-IL6/IL-Ralpha interaction in human HepG2 cells assessed as inhibition of IL-6-induced STAT3 activation by luciferase reporter gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2017
Entry Details Article
PubMed