Compile Data Set for Download or QSAR
Report error Found 175 Enz. Inhib. hit(s) with Target = 'Inosine-5'-monophosphate dehydrogenase 1'
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
Brandeis University

Curated by ChEMBL
LigandPNGBDBM50294184(CHEMBL561640 | N-(4-chlorophenyl)-2-phenoxypropana...)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of human recombinant IMPDH1 expressed in Escherichia coli guaB assessed as NADH production by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
Brandeis University

Curated by ChEMBL
LigandPNGBDBM19264(CHEMBL866 | Myfortic | (4E)-6-(4-hydroxy-6-methoxy...)
Affinity DataIC50: 19nMAssay Description:Inhibition of human IMPDH1 expressed in Escherichia coli strain BL21(DE3) after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
Brandeis University

Curated by ChEMBL
LigandPNGBDBM19264(CHEMBL866 | Myfortic | (4E)-6-(4-hydroxy-6-methoxy...)
Affinity DataIC50: 20nMAssay Description:In vitro inhibition of inosine Inosine-5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
Brandeis University

Curated by ChEMBL
LigandPNGBDBM19264(CHEMBL866 | Myfortic | (4E)-6-(4-hydroxy-6-methoxy...)
Affinity DataIC50: 32nMAssay Description:Inhibition of human IMPDH1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
Brandeis University

Curated by ChEMBL
LigandPNGBDBM50185589((E)-2-(4-(6-ethyl-4-hydroxy-7-methyl-3-oxo-1,3-dih...)
Affinity DataIC50: 37nMAssay Description:Inhibition of human IMPDH1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
Brandeis University

Curated by ChEMBL
LigandPNGBDBM50185592((E)-(4-(6-ethyl-4-hydroxy-7-methyl-3-oxo-1,3-dihyd...)
Affinity DataIC50: 38nMAssay Description:Inhibition of human IMPDH1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Human)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50112565(N-tert-Butyl-N'-(3-methoxy-4-oxazol-5-yl-phenyl)-o...)
Affinity DataIC50: 40nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2018
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
Brandeis University

Curated by ChEMBL
LigandPNGBDBM50123317(7-Methoxy-6-oxazol-5-yl-2-p-tolyl-1H-quinolin-4-on...)
Affinity DataIC50: 46nMAssay Description:Inhibitory activity against inosine monophosphate dehydrogenase IMPDH type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
Brandeis University

Curated by ChEMBL
LigandPNGBDBM50123320(7-Methoxy-6-oxazol-5-yl-2-thiophen-3-yl-1H-quinoli...)
Affinity DataIC50: 55nMAssay Description:Inhibitory activity against inosine monophosphate dehydrogenase IMPDH type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
Brandeis University

Curated by ChEMBL
LigandPNGBDBM50119045(1-(3-Methoxy-4-oxazol-5-yl-phenyl)-3-m-tolyl-urea ...)
Affinity DataIC50: 55nMAssay Description:Inhibitory activity against inosine monophosphate dehydrogenase IMPDH type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
Brandeis University

Curated by ChEMBL
LigandPNGBDBM19264(CHEMBL866 | Myfortic | (4E)-6-(4-hydroxy-6-methoxy...)
Affinity DataIC50: 55nMAssay Description:Inhibitory activity against inosine monophosphate dehydrogenase IMPDH type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
Brandeis University

Curated by ChEMBL
LigandPNGBDBM50185586((E)-4-(6-ethyl-4-hydroxy-7-methyl-3-oxo-1,3-dihydr...)
Affinity DataIC50: 71nMAssay Description:Inhibition of human IMPDH1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
Brandeis University

Curated by ChEMBL
LigandPNGBDBM50123335(2-(3,4-Dimethyl-phenyl)-7-methoxy-6-oxazol-5-yl-1H...)
Affinity DataIC50: 83nMAssay Description:Inhibitory activity against inosine monophosphate dehydrogenase IMPDH type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
Brandeis University

Curated by ChEMBL
LigandPNGBDBM50123332(7-Methoxy-2-(4-methoxy-phenyl)-6-oxazol-5-yl-1H-qu...)
Affinity DataIC50: 90nMAssay Description:Inhibitory activity against inosine monophosphate dehydrogenase IMPDH type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
Brandeis University

Curated by ChEMBL
LigandPNGBDBM50123324(7-Methoxy-6-oxazol-5-yl-2-phenyl-1H-quinolin-4-one...)
Affinity DataIC50: 99nMAssay Description:Inhibitory activity against inosine monophosphate dehydrogenase IMPDH type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
Brandeis University

Curated by ChEMBL
LigandPNGBDBM50123321(7-Methoxy-6-oxazol-5-yl-2-m-tolyl-1H-quinolin-4-on...)
Affinity DataIC50: 150nMAssay Description:Inhibitory activity against inosine monophosphate dehydrogenase IMPDH type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
Brandeis University

Curated by ChEMBL
LigandPNGBDBM50054017(6-(4,6-dihydroxy-7-methyl-3-oxo-1,3-dihydroisobenz...)
Affinity DataIC50: 150nMAssay Description:Inhibition of human IMPDH1 expressed in Escherichia coli strain BL21(DE3) after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
Brandeis University

Curated by ChEMBL
LigandPNGBDBM50126005(2-Benzo[b]thiophen-3-yl-6-methoxy-5-oxazol-5-yl-1H...)
Affinity DataIC50: 160nMAssay Description:Inhibition of 5'-inosine monophosphate dehydrogenase type I (IMPDH I)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Human)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50112568(N-tert-Butyl-N'-(3-chloro-4-oxazol-5-yl-phenyl)-ox...)
Affinity DataIC50: 180nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2018
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Human)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50220617(CHEMBL47928)
Affinity DataIC50: 200nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2018
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
Brandeis University

Curated by ChEMBL
LigandPNGBDBM50228085(N-hydroxy-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,...)
Affinity DataIC50: 350nMAssay Description:Inhibition of human IMPDH1 expressed in Escherichia coli strain BL21(DE3) after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Human)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50220681(CHEMBL45658)
Affinity DataIC50: 430nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2018
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Human)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50220682(CHEMBL46358)
Affinity DataIC50: 470nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2018
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Human)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50220679(CHEMBL45504)
Affinity DataIC50: 730nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2018
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
Brandeis University

Curated by ChEMBL
LigandPNGBDBM50331099(7-Hydroxy-6-((E)-6-hydroxy-3-methyl-hex-2-enyl)-5-...)
Affinity DataIC50: 770nMAssay Description:Inhibition of human IMPDH1 expressed in Escherichia coli strain BL21(DE3) after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Human)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50220673(CHEMBL48668)
Affinity DataIC50: 910nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2018
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
Brandeis University

Curated by ChEMBL
LigandPNGBDBM50010605(CHEMBL424363 | 6-(4-Hydroxy-6-methoxy-7-methyl-3-o...)
Affinity DataIC50: 940nMAssay Description:In vitro inhibition of inosine Inosine-5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
Brandeis University

Curated by ChEMBL
LigandPNGBDBM50119012(1H-Indole-2-carboxylic acid (3-methoxy-4-oxazol-5-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity of compound was evaluated against the Inosine-5'-monophosphate dehydrogenase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
Brandeis University

Curated by ChEMBL
LigandPNGBDBM50010602(CHEMBL168861 | 3-[2-(4-Hydroxy-6-methoxy-7-methyl-...)
Affinity DataIC50: 1.10E+3nMAssay Description:In vitro inhibition of inosine Inosine-5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
Brandeis University

Curated by ChEMBL
LigandPNGBDBM50010604(CHEMBL167966 | 7-(4-Hydroxy-6-methoxy-7-methyl-3-o...)
Affinity DataIC50: 1.20E+3nMAssay Description:In vitro inhibition of inosine Inosine-5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Human)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50220616(CHEMBL47830)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2018
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Human)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50220671(CHEMBL44696)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2018
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
Brandeis University

Curated by ChEMBL
LigandPNGBDBM50331100(methyl 6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-d...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human IMPDH1 expressed in Escherichia coli strain BL21(DE3) after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
Brandeis University

Curated by ChEMBL
LigandPNGBDBM50010609(CHEMBL170557 | 7-(4-Hydroxy-6-methoxy-7-methyl-3-o...)
Affinity DataIC50: 1.80E+3nMAssay Description:In vitro inhibition of inosine Inosine-5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
Brandeis University

Curated by ChEMBL
LigandPNGBDBM50010611(CHEMBL101365 | 6-(4-Hydroxy-6-methoxy-7-methyl-3-o...)
Affinity DataIC50: 1.80E+3nMAssay Description:In vitro inhibition of inosine Inosine-5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Human)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50220672(CHEMBL416079)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2018
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
Brandeis University

Curated by ChEMBL
LigandPNGBDBM50010612(CHEMBL169309 | 7-(4-Hydroxy-6-methoxy-7-methyl-3-o...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro inhibition of inosine Inosine-5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
Brandeis University

Curated by ChEMBL
LigandPNGBDBM50010606(CHEMBL169198 | 6-(4-Hydroxy-6-methoxy-7-methyl-3-o...)
Affinity DataIC50: 2.60E+3nMAssay Description:In vitro inhibition of inosine Inosine-5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
Brandeis University

Curated by ChEMBL
LigandPNGBDBM50010610(CHEMBL165934 | 3-[2,2-Difluoro-3-(4-hydroxy-6-meth...)
Affinity DataIC50: 2.60E+3nMAssay Description:In vitro inhibition of inosine Inosine-5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
Brandeis University

Curated by ChEMBL
LigandPNGBDBM50010603(CHEMBL443556 | 3-[2,2-Dibromo-3-(4-hydroxy-6-metho...)
Affinity DataIC50: 3.10E+3nMAssay Description:In vitro inhibition of inosine Inosine-5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
Brandeis University

Curated by ChEMBL
LigandPNGBDBM50331098(6-(4-acetoxy-6-methoxy-7-methyl-3-oxo-1,3-dihydroi...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of human IMPDH1 expressed in Escherichia coli strain BL21(DE3) after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Human)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50220615(CHEMBL47067)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2018
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Human)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50220618(CHEMBL45771)
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2018
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
Brandeis University

Curated by ChEMBL
LigandPNGBDBM50010608(CHEMBL165933 | 3-(4-Hydroxy-6-methoxy-7-methyl-3-o...)
Affinity DataIC50: 1.09E+4nMAssay Description:In vitro inhibition of inosine Inosine-5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Human)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50112570(N-tert-Butyl-N'-[4-(4-methyl-oxazol-5-yl)-phenyl]-...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2018
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Human)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50220683(CHEMBL432699)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2018
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Human)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50220620(CHEMBL297980)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2018
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Human)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50220675(CHEMBL47362)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2018
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Human)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50127715(3-Methoxy-4-oxazol-5-yl-phenylamine | 3-methoxy-4-...)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2018
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Human)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50112571(N-tert-Butyl-N'-(4-oxazol-5-yl-phenyl)-oxalamide |...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2018
Entry Details Article
PubMed
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