Compile Data Set for Download or QSAR
Report error Found 282 Enz. Inhib. hit(s) with Target = 'Induced myeloid leukemia cell differentiation protein Mcl-1 [172-327]'
LigandPNGBDBM50400183(Purpuro (Ligand 1) | XANTHOPURPURIN)
Affinity DataKd:  1.35E+6nMpH: 8.0 T: 2°CAssay Description:ITC experiments were carried out using iTC200 (Microcal LLC, Northampton, MA, USA) with each of the compounds 1-6 and Mcl-1 protein. The heat of rea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2014
Entry Details Article
PubMed
LigandPNGBDBM50400182(CHEMBL2180322 | 2,3‐dihydroxyanthracene̴...)
Affinity DataKd:  1.85E+3nMpH: 8.0 T: 2°CAssay Description:ITC experiments were carried out using iTC200 (Microcal LLC, Northampton, MA, USA) with each of the compounds 1-6 and Mcl-1 protein. The heat of rea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2014
Entry Details Article
PubMed
LigandPNGBDBM50400181(CHEMBL2180321 | 6‐bromo‐2,3‐dihy...)
Affinity DataKd:  1.84E+3nMpH: 8.0 T: 2°CAssay Description:ITC experiments were carried out using iTC200 (Microcal LLC, Northampton, MA, USA) with each of the compounds 1-6 and Mcl-1 protein. The heat of rea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2014
Entry Details Article
PubMed
LigandPNGBDBM50400179(CHEMBL2180319 | 2,3‐dihydroxy‐6‐...)
Affinity DataKd:  1.47E+3nMpH: 8.0 T: 2°CAssay Description:ITC experiments were carried out using iTC200 (Microcal LLC, Northampton, MA, USA) with each of the compounds 1-6 and Mcl-1 protein. The heat of rea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2014
Entry Details Article
PubMed
LigandPNGBDBM50400178(CHEMBL2180318 | 2,3‐dihydroxy‐6‐...)
Affinity DataKd:  950nMpH: 8.0 T: 2°CAssay Description:ITC experiments were carried out using iTC200 (Microcal LLC, Northampton, MA, USA) with each of the compounds 1-6 and Mcl-1 protein. The heat of rea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2014
Entry Details Article
PubMed
LigandPNGBDBM50400180(CHEMBL2180320 | 2,3‐dihydroxy‐6‐...)
Affinity DataKd:  238nMpH: 8.0 T: 2°CAssay Description:ITC experiments were carried out using iTC200 (Microcal LLC, Northampton, MA, USA) with each of the compounds 1-6 and Mcl-1 protein. The heat of rea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2014
Entry Details Article
PubMed
LigandPNGBDBM38065(US10093640, Example 50 | 4-chloro-3-(3-(4-chloro-3...)
Affinity DataKi: <100nMAssay Description:The assay was run using a fluorescein isothiocyanate-labeled BH3 peptide derived from Bak (FITC-AHx-GQVGRQLAIIGDDINR-NH2) that was purchased from Gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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LigandPNGBDBM38066(US10093640, Example 51 | 4-chloro-3-(3-(4-chloro-3...)
Affinity DataKi: <100nMAssay Description:The assay was run using a fluorescein isothiocyanate-labeled BH3 peptide derived from Bak (FITC-AHx-GQVGRQLAIIGDDINR-NH2) that was purchased from Gen...More data for this Ligand-Target Pair
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Date in BDB:
7/6/2021
Entry Details
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LigandPNGBDBM38101(US10093640, Example 88 | 3-(3-(4-chloro-3,5-dimeth...)
Affinity DataKi: <100nMAssay Description:The assay was run using a fluorescein isothiocyanate-labeled BH3 peptide derived from Bak (FITC-AHx-GQVGRQLAIIGDDINR-NH2) that was purchased from Gen...More data for this Ligand-Target Pair
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Date in BDB:
7/6/2021
Entry Details
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LigandPNGBDBM50160000(CHEMBL3786018 | US10093640, Example 89 | US1084403...)
Affinity DataKi: <100nMAssay Description:The assay was run using a fluorescein isothiocyanate-labeled BH3 peptide derived from Bak (FITC-AHx-GQVGRQLAIIGDDINR-NH2) that was purchased from Gen...More data for this Ligand-Target Pair
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Date in BDB:
7/6/2021
Entry Details
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LigandPNGBDBM38103(US10093640, Example 90 | 3-(3-(4-chloro-3,5-dimeth...)
Affinity DataKi: <100nMAssay Description:The assay was run using a fluorescein isothiocyanate-labeled BH3 peptide derived from Bak (FITC-AHx-GQVGRQLAIIGDDINR-NH2) that was purchased from Gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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LigandPNGBDBM38104(US10093640, Example 92 | 3-(3-(4-chloro-3,5-dimeth...)
Affinity DataKi: <100nMAssay Description:The assay was run using a fluorescein isothiocyanate-labeled BH3 peptide derived from Bak (FITC-AHx-GQVGRQLAIIGDDINR-NH2) that was purchased from Gen...More data for this Ligand-Target Pair
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Date in BDB:
7/6/2021
Entry Details
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LigandPNGBDBM38109(US10093640, Example 98 | 3-(3-(4-chloro-3,5-dimeth...)
Affinity DataKi: <100nMAssay Description:The assay was run using a fluorescein isothiocyanate-labeled BH3 peptide derived from Bak (FITC-AHx-GQVGRQLAIIGDDINR-NH2) that was purchased from Gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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LigandPNGBDBM38110(US10093640, Example 99 | 3-(3-(4-chloro-3,5-dimeth...)
Affinity DataKi: <100nMAssay Description:The assay was run using a fluorescein isothiocyanate-labeled BH3 peptide derived from Bak (FITC-AHx-GQVGRQLAIIGDDINR-NH2) that was purchased from Gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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LigandPNGBDBM38112(US10093640, Example 100 | 3-(3-(4-chloro-3,5-dimet...)
Affinity DataKi: <100nMAssay Description:The assay was run using a fluorescein isothiocyanate-labeled BH3 peptide derived from Bak (FITC-AHx-GQVGRQLAIIGDDINR-NH2) that was purchased from Gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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LigandPNGBDBM38114(US10093640, Example 101 | 3-(3-(4-chloro-3,5-dimet...)
Affinity DataKi: <100nMAssay Description:The assay was run using a fluorescein isothiocyanate-labeled BH3 peptide derived from Bak (FITC-AHx-GQVGRQLAIIGDDINR-NH2) that was purchased from Gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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LigandPNGBDBM38115(US10093640, Example 102 | 3-(3-(4-chloro-3,5-dimet...)
Affinity DataKi: <100nMAssay Description:The assay was run using a fluorescein isothiocyanate-labeled BH3 peptide derived from Bak (FITC-AHx-GQVGRQLAIIGDDINR-NH2) that was purchased from Gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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LigandPNGBDBM38119(US10093640, Example 103 | 3-(3-(4-chloro-3,5-dimet...)
Affinity DataKi: <100nMAssay Description:The assay was run using a fluorescein isothiocyanate-labeled BH3 peptide derived from Bak (FITC-AHx-GQVGRQLAIIGDDINR-NH2) that was purchased from Gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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LigandPNGBDBM38120(US10093640, Example 104 | 3-(3-(4-chloro-3,5-dimet...)
Affinity DataKi: <100nMAssay Description:The assay was run using a fluorescein isothiocyanate-labeled BH3 peptide derived from Bak (FITC-AHx-GQVGRQLAIIGDDINR-NH2) that was purchased from Gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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LigandPNGBDBM38131(US10093640, Example 113 | 4-bromo-3-(3-(4-chloro-3...)
Affinity DataKi: <100nMAssay Description:The assay was run using a fluorescein isothiocyanate-labeled BH3 peptide derived from Bak (FITC-AHx-GQVGRQLAIIGDDINR-NH2) that was purchased from Gen...More data for this Ligand-Target Pair
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Date in BDB:
7/6/2021
Entry Details
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LigandPNGBDBM38134(US10093640, Example 116 | 3-(3-(4-chloro-3,5-dimet...)
Affinity DataKi: <100nMAssay Description:The assay was run using a fluorescein isothiocyanate-labeled BH3 peptide derived from Bak (FITC-AHx-GQVGRQLAIIGDDINR-NH2) that was purchased from Gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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LigandPNGBDBM38141(US10093640, Example 121 | 6-chloro-3-(3-(4-chloro-...)
Affinity DataKi: <100nMAssay Description:The assay was run using a fluorescein isothiocyanate-labeled BH3 peptide derived from Bak (FITC-AHx-GQVGRQLAIIGDDINR-NH2) that was purchased from Gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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LigandPNGBDBM38143(US10093640, Example 123 | 3-(3-(4-chloro-3,5-dimet...)
Affinity DataKi: <100nMAssay Description:The assay was run using a fluorescein isothiocyanate-labeled BH3 peptide derived from Bak (FITC-AHx-GQVGRQLAIIGDDINR-NH2) that was purchased from Gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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LigandPNGBDBM38144(US10093640, Example 124 | 7-(3-((4-(4-acetylpipera...)
Affinity DataKi: <100nMAssay Description:The assay was run using a fluorescein isothiocyanate-labeled BH3 peptide derived from Bak (FITC-AHx-GQVGRQLAIIGDDINR-NH2) that was purchased from Gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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LigandPNGBDBM38147(US10093640, Example 127 | 3-(3-(4-chloro-3,5-dimet...)
Affinity DataKi: <100nMAssay Description:The assay was run using a fluorescein isothiocyanate-labeled BH3 peptide derived from Bak (FITC-AHx-GQVGRQLAIIGDDINR-NH2) that was purchased from Gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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LigandPNGBDBM38150(US10093640, Example 130 | 3-(3-(4-chloro-3,5-dimet...)
Affinity DataKi: <100nMAssay Description:The assay was run using a fluorescein isothiocyanate-labeled BH3 peptide derived from Bak (FITC-AHx-GQVGRQLAIIGDDINR-NH2) that was purchased from Gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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LigandPNGBDBM50159994(CHEMBL3786996 | US10844032, Example 170)
Affinity DataKi: <100nMAssay Description:The assay was run using a fluorescein isothiocyanate-labeled BH3 peptide derived from Bak (FITC-AHx-GQVGRQLAIIGDDINR-NH2) that was purchased from Gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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LigandPNGBDBM286515(US10093640, Example 204 | 3-(3-(4-chloro-3,5-dimet...)
Affinity DataKi: <100nMAssay Description:The assay was run using a fluorescein isothiocyanate-labeled BH3 peptide derived from Bak (FITC-AHx-GQVGRQLAIIGDDINR-NH2) that was purchased from Gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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LigandPNGBDBM286516(US10093640, Example 205 | 3-(3-(4-chloro-3,5-dimet...)
Affinity DataKi: <100nMAssay Description:The assay was run using a fluorescein isothiocyanate-labeled BH3 peptide derived from Bak (FITC-AHx-GQVGRQLAIIGDDINR-NH2) that was purchased from Gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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LigandPNGBDBM286517(US10093640, Example 206 | 3-(3-(4-chloro-3,5-dimet...)
Affinity DataKi: <100nMAssay Description:The assay was run using a fluorescein isothiocyanate-labeled BH3 peptide derived from Bak (FITC-AHx-GQVGRQLAIIGDDINR-NH2) that was purchased from Gen...More data for this Ligand-Target Pair
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Date in BDB:
7/6/2021
Entry Details
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LigandPNGBDBM473418(US10844032, Example 207 | Preparation of N-((2-(1-...)
Affinity DataKi: <100nMAssay Description:The assay was run using a fluorescein isothiocyanate-labeled BH3 peptide derived from Bak (FITC-AHx-GQVGRQLAIIGDDINR-NH2) that was purchased from Gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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LigandPNGBDBM50159949(CHEMBL3787178 | US10093640, Example 216 | US108440...)
Affinity DataKi: <100nMAssay Description:The assay was run using a fluorescein isothiocyanate-labeled BH3 peptide derived from Bak (FITC-AHx-GQVGRQLAIIGDDINR-NH2) that was purchased from Gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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LigandPNGBDBM50160018(CHEMBL3785155 | US10093640, Example 226 | US108440...)
Affinity DataKi: <100nMAssay Description:The assay was run using a fluorescein isothiocyanate-labeled BH3 peptide derived from Bak (FITC-AHx-GQVGRQLAIIGDDINR-NH2) that was purchased from Gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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LigandPNGBDBM289018(US10093640, Example 230 | 6-chloro-3-(3-(4-chloro-...)
Affinity DataKi: <100nMAssay Description:The assay was run using a fluorescein isothiocyanate-labeled BH3 peptide derived from Bak (FITC-AHx-GQVGRQLAIIGDDINR-NH2) that was purchased from Gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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LigandPNGBDBM50159933(CHEMBL3786092 | US10093640, Example 232 | US108440...)
Affinity DataKi: <100nMAssay Description:The assay was run using a fluorescein isothiocyanate-labeled BH3 peptide derived from Bak (FITC-AHx-GQVGRQLAIIGDDINR-NH2) that was purchased from Gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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LigandPNGBDBM289022(US10093640, Example 233 | 6-chloro-3-(3-(4-chloro-...)
Affinity DataKi: <100nMAssay Description:The assay was run using a fluorescein isothiocyanate-labeled BH3 peptide derived from Bak (FITC-AHx-GQVGRQLAIIGDDINR-NH2) that was purchased from Gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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LigandPNGBDBM50159954(CHEMBL3785998 | US10093640, Example 237 | US108440...)
Affinity DataKi: <100nMAssay Description:The assay was run using a fluorescein isothiocyanate-labeled BH3 peptide derived from Bak (FITC-AHx-GQVGRQLAIIGDDINR-NH2) that was purchased from Gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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LigandPNGBDBM50159945(CHEMBL3785666 | US10093640, Example 253 | US108440...)
Affinity DataKi: <100nMAssay Description:The assay was run using a fluorescein isothiocyanate-labeled BH3 peptide derived from Bak (FITC-AHx-GQVGRQLAIIGDDINR-NH2) that was purchased from Gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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LigandPNGBDBM50159940(CHEMBL3785228 | US10093640, Example 255 | US108440...)
Affinity DataKi: <100nMAssay Description:The assay was run using a fluorescein isothiocyanate-labeled BH3 peptide derived from Bak (FITC-AHx-GQVGRQLAIIGDDINR-NH2) that was purchased from Gen...More data for this Ligand-Target Pair
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Date in BDB:
7/6/2021
Entry Details
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LigandPNGBDBM289051(US10093640, Example 260 | -chloro-3-(3-(4-chloro-3...)
Affinity DataKi: <100nMAssay Description:The assay was run using a fluorescein isothiocyanate-labeled BH3 peptide derived from Bak (FITC-AHx-GQVGRQLAIIGDDINR-NH2) that was purchased from Gen...More data for this Ligand-Target Pair
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Date in BDB:
7/6/2021
Entry Details
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LigandPNGBDBM289052(US10093640, Example 261 | 5-(N-(6-chloro-3-(3-(4-c...)
Affinity DataKi: <100nMAssay Description:The assay was run using a fluorescein isothiocyanate-labeled BH3 peptide derived from Bak (FITC-AHx-GQVGRQLAIIGDDINR-NH2) that was purchased from Gen...More data for this Ligand-Target Pair
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Date in BDB:
7/6/2021
Entry Details
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LigandPNGBDBM289055(US10093640, Example 264 | methyl 5-(N-(6-chloro-3-...)
Affinity DataKi: <100nMAssay Description:The assay was run using a fluorescein isothiocyanate-labeled BH3 peptide derived from Bak (FITC-AHx-GQVGRQLAIIGDDINR-NH2) that was purchased from Gen...More data for this Ligand-Target Pair
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Date in BDB:
7/6/2021
Entry Details
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LigandPNGBDBM289058(US10093640, Example 266 | 5-(N-(6-chloro-3-(3-(4-c...)
Affinity DataKi: <100nMAssay Description:The assay was run using a fluorescein isothiocyanate-labeled BH3 peptide derived from Bak (FITC-AHx-GQVGRQLAIIGDDINR-NH2) that was purchased from Gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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LigandPNGBDBM289071(US10093640, Example 279 | 3-(3-(4-chloro-3,5-dimet...)
Affinity DataKi: <100nMAssay Description:The assay was run using a fluorescein isothiocyanate-labeled BH3 peptide derived from Bak (FITC-AHx-GQVGRQLAIIGDDINR-NH2) that was purchased from Gen...More data for this Ligand-Target Pair
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Date in BDB:
7/6/2021
Entry Details
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LigandPNGBDBM289072(US10093640, Example 299 | 3-(3-(4-chloro-3,5-dimet...)
Affinity DataKi: <100nMAssay Description:The assay was run using a fluorescein isothiocyanate-labeled BH3 peptide derived from Bak (FITC-AHx-GQVGRQLAIIGDDINR-NH2) that was purchased from Gen...More data for this Ligand-Target Pair
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Date in BDB:
7/6/2021
Entry Details
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LigandPNGBDBM289075(US10093640, Example 300 | 3-(3-(4-chloro-3,5-dimet...)
Affinity DataKi: <100nMAssay Description:The assay was run using a fluorescein isothiocyanate-labeled BH3 peptide derived from Bak (FITC-AHx-GQVGRQLAIIGDDINR-NH2) that was purchased from Gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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LigandPNGBDBM289076(US10093640, Example 301 | 3-(3-(4-chloro-3,5-dimet...)
Affinity DataKi: <100nMAssay Description:The assay was run using a fluorescein isothiocyanate-labeled BH3 peptide derived from Bak (FITC-AHx-GQVGRQLAIIGDDINR-NH2) that was purchased from Gen...More data for this Ligand-Target Pair
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Date in BDB:
7/6/2021
Entry Details
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LigandPNGBDBM289078(US10093640, Example 302 | 3-(3-(4-chloro-3,5-dimet...)
Affinity DataKi: <100nMAssay Description:The assay was run using a fluorescein isothiocyanate-labeled BH3 peptide derived from Bak (FITC-AHx-GQVGRQLAIIGDDINR-NH2) that was purchased from Gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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LigandPNGBDBM289079(US10093640, Example 303 | 3-(3-(4-chloro-3,5-dimet...)
Affinity DataKi: <100nMAssay Description:The assay was run using a fluorescein isothiocyanate-labeled BH3 peptide derived from Bak (FITC-AHx-GQVGRQLAIIGDDINR-NH2) that was purchased from Gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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LigandPNGBDBM289080(US10093640, Example 304 | 3-(3-(4-chloro-3,5-dimet...)
Affinity DataKi: <100nMAssay Description:The assay was run using a fluorescein isothiocyanate-labeled BH3 peptide derived from Bak (FITC-AHx-GQVGRQLAIIGDDINR-NH2) that was purchased from Gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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