Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with Target = 'Hydroxyacylglutathione hydrolase, mitochondrial'
LigandPNGBDBM50582857(CHEMBL5091922)
Affinity DataIC50: 5.20E+4nMAssay Description:Inhibition of recombinant human Glyoxalase-2 assessed as reduction of substrate level using S-D-lactoylglutathione as substrate by spectrophotometric...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetHydroxyacylglutathione hydrolase, mitochondrial(Bovine)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50126960(CHEMBL3629116)
Affinity DataKi:  81nMAssay Description:Inhibition of bovine liver glyoxalase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetHydroxyacylglutathione hydrolase, mitochondrial(Bovine)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50126961(CHEMBL3629115)
Affinity DataKi:  138nMAssay Description:Inhibition of bovine liver glyoxalase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
LigandPNGBDBM50039111(S-(N-Hydroxy-N-(4-bromophenyl)carbamoyl)glutathion...)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition constants obtained from using the enediol analogs as competitive inhibitors for the inhibition of the hydrolysis of S-D-lactoylglutathione...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetHydroxyacylglutathione hydrolase, mitochondrial(Bovine)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50092824(S-(N-4chlorophenyl-N-hydroxycarbamoyl)glutathione ...)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition of bovine liver glyoxalase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
LigandPNGBDBM50039108(S-(N-Hydroxy-N-(4-chlorophenyl)carbamoyl)glutathio...)
Affinity DataKi:  3.40E+3nMAssay Description:Inhibition constants obtained from using the enediol analogs as competitive inhibitors for the inhibition of the hydrolysis of S-D-lactoylglutathione...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
LigandPNGBDBM50026371(2-Amino-4-[1-(carboxymethyl-carbamoyl)-2-(4-nitro-...)
Affinity DataKi:  6.50E+3nMAssay Description:Binding affinity towards rat liver glyoxalase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50026368(2-Amino-4-[1-(carboxymethyl-carbamoyl)-2-(3-nitro-...)
Affinity DataKi:  9.00E+3nMAssay Description:Binding affinity towards rat liver glyoxalase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50039113(S-(N-Hydroxy-N-phenylcarbamoyl)glutathione)
Affinity DataKi:  1.10E+4nMAssay Description:Inhibition constant for the inhibition of the hydrolysis of S-D-lactoylglutathione by glyoxalase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
LigandPNGBDBM50026370(2-Amino-4-[1-(carboxymethyl-carbamoyl)-2-(2-nitro-...)
Affinity DataKi:  1.50E+4nMAssay Description:Binding affinity towards rat liver glyoxalase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50026369(2-Amino-4-[2-benzyloxycarbonylsulfanyl-1-(carboxym...)
Affinity DataKi:  6.50E+4nMAssay Description:Binding affinity towards rat liver glyoxalase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50028202((S)-2-Amino-4-[(R)-2-benzyloxycarbonylsulfanyl-1-(...)
Affinity DataKi:  6.50E+4nMAssay Description:In vivo inhibitory activity against glyoxalase II in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50039110(S-(N-Methyl-N-hydroxycarbomyl)ethylglutathione)
Affinity DataKi:  4.26E+5nMAssay Description:Inhibition constants obtained from using the enediol analogs as competitive inhibitors for the inhibition of the hydrolysis of S-D-lactoylglutathione...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed