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Report error Found 8 Enz. Inhib. hit(s) with Target = 'Histone-lysine N-methyltransferase KMT5B'
TargetHistone-lysine N-methyltransferase KMT5B(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50590375(CHEMBL5187396)
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase KMT5B(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM588052((2R)-7-chloro-2-[trans-4-(dimethylamino)cyclohexyl...)
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In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase KMT5B(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM223981(A-196 (3) | 6,7-Dichloro-N-cyclopentyl-4-(pyridin-...)
Affinity DataIC50: 25nMpH: 8.0 T: 2°CAssay Description:Experiments were performed in triplicate at room temperature with 1 h incubation of 10 μl reaction mixture in buffer of 20 mM Tris-HCl, pH 8.0, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2017
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase KMT5B(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM223980(6,7-Dichloro-N-cyclopentylquinolin-4-amine (2))
Affinity DataIC50: 590nMpH: 8.0 T: 2°CAssay Description:Experiments were performed in triplicate at room temperature with 1 h incubation of 10 μl reaction mixture in buffer of 20 mM Tris-HCl, pH 8.0, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2017
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase KMT5B(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM223979(7-Chloro-N-cyclopentylquinolin-4-amine (1))
Affinity DataIC50: 5.90E+3nMpH: 8.0 T: 2°CAssay Description:Experiments were performed in triplicate at room temperature with 1 h incubation of 10 μl reaction mixture in buffer of 20 mM Tris-HCl, pH 8.0, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2017
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase KMT5B(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM223982(A-197 (4) | (6,7-Dichloro-4-(cyclopentylamino)phth...)
Affinity DataIC50: 1.00E+4nMpH: 8.0 T: 2°CAssay Description:Experiments were performed in triplicate at room temperature with 1 h incubation of 10 μl reaction mixture in buffer of 20 mM Tris-HCl, pH 8.0, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2017
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase KMT5B(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50051117(CHEMBL3318285)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of SUV420H1 (unknown origin) assessed as incorporation of tritium-labeled methyl group to lysine or arginine residues of peptide substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase KMT5B(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50075071(CHEMBL3414619)
Affinity DataIC50: 1.00E+5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed