Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with Target = 'Histone deacetylase 6 [440-798]'
TargetHistone deacetylase 6 [440-798](Zebrafish)
University of Pennsylvania

LigandPNGBDBM198125(fl-SAHA)
Affinity DataKd:  50nMT: 2°CAssay Description:The fluorescence anisotropy assay was performed with fluorescein-labeled SAHA (fl-SAHA, gift of C. Fierke, University of Michigan) and measured using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details Article
PubMed
TargetHistone deacetylase 6 [440-798](Zebrafish)
University of Pennsylvania

LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataKi:  0.600nM ΔG°:  -52.6kJ/mole IC50: 1.10nMT: 2°CAssay Description:The fluorescence anisotropy assay was performed with fluorescein-labeled SAHA (fl-SAHA, gift of C. Fierke, University of Michigan) and measured using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 6 [440-798](Zebrafish)
University of Pennsylvania

LigandPNGBDBM198120(TSA)
Affinity DataKi:  0.800nM ΔG°:  -51.9kJ/mole IC50: 1.40nMT: 2°CAssay Description:The fluorescence anisotropy assay was performed with fluorescein-labeled SAHA (fl-SAHA, gift of C. Fierke, University of Michigan) and measured using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details Article
PubMed
TargetHistone deacetylase 6 [440-798](Zebrafish)
University of Pennsylvania

LigandPNGBDBM198121(HPOB)
Affinity DataKi:  1nM ΔG°:  -51.4kJ/mole IC50: 1.80nMT: 2°CAssay Description:The fluorescence anisotropy assay was performed with fluorescein-labeled SAHA (fl-SAHA, gift of C. Fierke, University of Michigan) and measured using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 6 [440-798](Zebrafish)
University of Pennsylvania

LigandPNGBDBM25150(Belinostat | (2E)-N-hydroxy-3-[3-(phenylsulfamoyl)...)
Affinity DataKi:  1.10nM ΔG°:  -51.1kJ/mole IC50: 1.90nMT: 2°CAssay Description:The fluorescence anisotropy assay was performed with fluorescein-labeled SAHA (fl-SAHA, gift of C. Fierke, University of Michigan) and measured using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 6 [440-798](Zebrafish)
University of Pennsylvania

LigandPNGBDBM198124(Panobinostat)
Affinity DataKi:  1.40nM ΔG°:  -50.5kJ/mole IC50: 2.5nMT: 2°CAssay Description:The fluorescence anisotropy assay was performed with fluorescein-labeled SAHA (fl-SAHA, gift of C. Fierke, University of Michigan) and measured using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details Article
PubMed
TargetHistone deacetylase 6 [440-798](Zebrafish)
University of Pennsylvania

LigandPNGBDBM50123957(5-(4-Benzenesulfonylamino-phenyl)-pent-2-en-4-ynoi...)
Affinity DataKi:  4.30nM ΔG°:  -47.8kJ/mole IC50: 7.5nMT: 2°CAssay Description:The fluorescence anisotropy assay was performed with fluorescein-labeled SAHA (fl-SAHA, gift of C. Fierke, University of Michigan) and measured using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details Article
PubMed
TargetHistone deacetylase 6 [440-798](Zebrafish)
University of Pennsylvania

LigandPNGBDBM198122(HC toxin)
Affinity DataKi:  350nM ΔG°:  -36.8kJ/mole IC50: 600nMT: 2°CAssay Description:The fluorescence anisotropy assay was performed with fluorescein-labeled SAHA (fl-SAHA, gift of C. Fierke, University of Michigan) and measured using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details Article
PubMed
TargetHistone deacetylase 6 [440-798](Zebrafish)
University of Pennsylvania

LigandPNGBDBM198123(Trifluoroketone)
Affinity DataKi:  800nM ΔG°:  -34.8kJ/mole IC50: 1.40E+3nMT: 2°CAssay Description:The fluorescence anisotropy assay was performed with fluorescein-labeled SAHA (fl-SAHA, gift of C. Fierke, University of Michigan) and measured using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details Article
PubMed