Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with Target = 'High affinity immunoglobulin gamma Fc receptor I'
TargetHigh affinity immunoglobulin gamma Fc receptor I(Human)
Toronto General Research Institute

Curated by ChEMBL
LigandPNGBDBM50432926(CHEMBL2377172)
Affinity DataIC50: 100nMAssay Description:Inhibition of FCgamma receptor in human PBMC assessed as inhibition of opsonized RBC phagocytosis incubated for 1 hr prior to RBC addition measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetHigh affinity immunoglobulin gamma Fc receptor I(Human)
Toronto General Research Institute

Curated by ChEMBL
LigandPNGBDBM50303805(2-(4-(4-(4-(4-aminophenethylamino)-6-(3-aminopheny...)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of heat aggregated human IgG binding to human Fc-gamma-R1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetHigh affinity immunoglobulin gamma Fc receptor I(Human)
Toronto General Research Institute

Curated by ChEMBL
LigandPNGBDBM50021626(CHEMBL3298400)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IGFR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetHigh affinity immunoglobulin gamma Fc receptor I(Human)
Toronto General Research Institute

Curated by ChEMBL
LigandPNGBDBM50021618(CHEMBL3297762 | US9145418, 2)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IGFR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetHigh affinity immunoglobulin gamma Fc receptor I(Human)
Toronto General Research Institute

Curated by ChEMBL
LigandPNGBDBM50048357(CHEMBL3309990)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IGFR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
TargetHigh affinity immunoglobulin gamma Fc receptor I(Human)
Toronto General Research Institute

Curated by ChEMBL
LigandPNGBDBM50048362(CHEMBL3309995)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IGFR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
TargetHigh affinity immunoglobulin gamma Fc receptor I(Human)
Toronto General Research Institute

Curated by ChEMBL
LigandPNGBDBM50048364(CHEMBL3309997)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IGFR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
TargetHigh affinity immunoglobulin gamma Fc receptor I(Human)
Toronto General Research Institute

Curated by ChEMBL
LigandPNGBDBM50048365(CHEMBL3309998)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IGFR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
TargetHigh affinity immunoglobulin gamma Fc receptor I(Human)
Toronto General Research Institute

Curated by ChEMBL
LigandPNGBDBM50048374(CHEMBL3310151)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IGFR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
TargetHigh affinity immunoglobulin gamma Fc receptor I(Human)
Toronto General Research Institute

Curated by ChEMBL
LigandPNGBDBM50305006(5-(2-aminoethyl)-7-(7-(benzo[b]thiophen-2-yl)-1H-i...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IGFR1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetHigh affinity immunoglobulin gamma Fc receptor I(Human)
Toronto General Research Institute

Curated by ChEMBL
LigandPNGBDBM50327912(3-(4-Morpholin-4-yl-benzoylamino)-1H-thieno[3,2-c]...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetHigh affinity immunoglobulin gamma Fc receptor I(Human)
Toronto General Research Institute

Curated by ChEMBL
LigandPNGBDBM50343559(1-(2-HYDROXYETHYL)-8-[[5-(4-METHYLPIPERAZIN-1-YL)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IGFR1 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetHigh affinity immunoglobulin gamma Fc receptor I(Human)
Toronto General Research Institute

Curated by ChEMBL
LigandPNGBDBM50349102(CHEMBL1236095 | US11208696, Example 3)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHigh affinity immunoglobulin gamma Fc receptor I(Human)
Toronto General Research Institute

Curated by ChEMBL
LigandPNGBDBM16018(cid_8515 | SP 600125 | ChemBiol10705 Compound 4 | ...)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHigh affinity immunoglobulin gamma Fc receptor I(Human)
Toronto General Research Institute

Curated by ChEMBL
LigandPNGBDBM50317750(2-(4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)-3-fluoroph...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of IGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed