Compile Data Set for Download or QSAR
Report error Found 7799 Enz. Inhib. hit(s) with Target = 'Glucocorticoid receptor'
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM18627(Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...)
Affinity DataEC50:  0.600nMpH: 7.5Assay Description:GR-Mediated Antagonist Activity Assay- GR-mediated antagonist activity is measured in the presence of a concentration of dexamethasone empirically de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2007
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM50012202(CHEMBL300409 | 17-(2-Bromo-acetyl)-9-fluoro-11,17-...)
Affinity DataEC50:  8.30E+9nMAssay Description:Partial agonist (20%) effect against glucocorticoid induced transactivation of tyrosine aminotransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM50107354(5-Benzyl-10-methoxy-2,2,4-trimethyl-2,5-dihydro-1H...)
Affinity DataEC50:  255nMAssay Description:Effective concentration in HepG2 cells transfected with LUC gene (E-sel-Luc).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM50107346(10-Methoxy-2,2,4-trimethyl-5-propyl-2,5-dihydro-1H...)
Affinity DataEC50:  70nMAssay Description:Effective concentration in HepG2 cells transfected with LUC gene (E-sel-Luc).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM50107364(5-Isopropyl-10-methoxy-2,2,4-trimethyl-2,5-dihydro...)
Affinity DataEC50:  39nMAssay Description:Effective concentration in HepG2 cells transfected with LUC gene (E-sel-Luc).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM50107350(5-Benzyl-10-methoxy-2,2,4-trimethyl-2,5-dihydro-1H...)
Affinity DataEC50:  38nMAssay Description:The effective concentration in CV-1 cells for glucocorticoid response element activation (GRE).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM50107366(10-Methoxy-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-...)
Affinity DataEC50:  126nMAssay Description:Effective concentration in HepG2 cells transfected with LUC gene (E-sel-Luc).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM50107357(10-Methoxy-2,2,4,5-tetramethyl-2,5-dihydro-1H-6-ox...)
Affinity DataEC50: >5.00E+3nMAssay Description:The effective concentration in CV-1 cells for glucocorticoid response element activation (GRE).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM50107349(10-Methoxy-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-...)
Affinity DataEC50: >5.00E+3nMAssay Description:Effective concentration in HepG2 cells transfected with LUC gene (E-sel-Luc).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM19190((1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-...)
Affinity DataEC50:  3.30nMAssay Description:The effective concentration in CV-1 cells for glucocorticoid response element activation (GRE).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM50107365(5-Cyclohexyl-10-methoxy-2,2,4-trimethyl-2,5-dihydr...)
Affinity DataEC50:  204nMAssay Description:Effective concentration in HepG2 cells transfected with LUC gene (E-sel-Luc).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM50107356(10-Methoxy-2,2,4-trimethyl-5-prop-2-ynyl-2,5-dihyd...)
Affinity DataEC50:  27nMAssay Description:Effective concentration in HepG2 cells transfected with LUC gene (E-sel-Luc).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM50107347(5-Allyl-10-methoxy-2,2,4-trimethyl-2,5-dihydro-1H-...)
Affinity DataEC50:  450nMAssay Description:Effective concentration in HepG2 cells transfected with LUC gene (E-sel-Luc).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM50107347(5-Allyl-10-methoxy-2,2,4-trimethyl-2,5-dihydro-1H-...)
Affinity DataEC50:  520nMAssay Description:The effective concentration in CV-1 cells for glucocorticoid response element activation (GRE).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM50107361(10-Methoxy-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-...)
Affinity DataEC50: >5.00E+3nMAssay Description:Effective concentration in HepG2 cells transfected with LUC gene (E-sel-Luc).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM50107344(5-Isobutyl-10-methoxy-2,2,4-trimethyl-2,5-dihydro-...)
Affinity DataEC50:  223nMAssay Description:The effective concentration in CV-1 cells for glucocorticoid response element activation (GRE).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM50107359(5-Butyl-10-methoxy-2,2,4-trimethyl-2,5-dihydro-1H-...)
Affinity DataEC50:  405nMAssay Description:The effective concentration in CV-1 cells for glucocorticoid response element activation (GRE).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM19190((1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-...)
Affinity DataEC50:  2.60nMAssay Description:Effective concentration in HepG2 cells transfected with LUC gene (E-sel-Luc).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM50103249(10-Methoxy-2,2,4-trimethyl-5-(3-methylsulfanylmeth...)
Affinity DataEC50:  9nMAssay Description:The effective concentration in CV-1 cells for glucocorticoid response element activation (GRE).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM50107355(5-Ethyl-10-methoxy-2,2,4-trimethyl-2,5-dihydro-1H-...)
Affinity DataEC50:  90nMAssay Description:Effective concentration in HepG2 cells transfected with LUC gene (E-sel-Luc).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM50107353(5-But-3-enyl-10-methoxy-2,2,4-trimethyl-2,5-dihydr...)
Affinity DataEC50:  78nMAssay Description:The effective concentration in CV-1 cells for glucocorticoid response element activation (GRE).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM50107362(2-(10-Methoxy-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa...)
Affinity DataEC50: >5.00E+3nMAssay Description:The effective concentration in CV-1 cells for glucocorticoid response element activation (GRE).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM50107357(10-Methoxy-2,2,4,5-tetramethyl-2,5-dihydro-1H-6-ox...)
Affinity DataEC50:  15nMAssay Description:Effective concentration in HepG2 cells transfected with LUC gene (E-sel-Luc).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM50107350(5-Benzyl-10-methoxy-2,2,4-trimethyl-2,5-dihydro-1H...)
Affinity DataEC50:  18nMAssay Description:Effective concentration in HepG2 cells transfected with LUC gene (E-sel-Luc).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM50107348((10-Methoxy-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1...)
Affinity DataEC50: >5.00E+3nMAssay Description:The effective concentration in CV-1 cells for glucocorticoid response element activation (GRE).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM50107352(10-Methoxy-2,2,4-trimethyl-5-propenyl-2,5-dihydro-...)
Affinity DataEC50:  460nMAssay Description:The effective concentration in CV-1 cells for glucocorticoid response element activation (GRE).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM50107358(10-Methoxy-2,2,4-trimethyl-5-propenyl-2,5-dihydro-...)
Affinity DataEC50:  400nMAssay Description:The effective concentration in CV-1 cells for glucocorticoid response element activation (GRE).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM50107352(10-Methoxy-2,2,4-trimethyl-5-propenyl-2,5-dihydro-...)
Affinity DataEC50:  168nMAssay Description:Effective concentration in HepG2 cells transfected with LUC gene (E-sel-Luc).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM50107345([2-(10-Methoxy-2,2,4-trimethyl-2,5-dihydro-1H-6-ox...)
Affinity DataEC50:  306nMAssay Description:Effective concentration in HepG2 cells transfected with LUC gene (E-sel-Luc).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM50107345([2-(10-Methoxy-2,2,4-trimethyl-2,5-dihydro-1H-6-ox...)
Affinity DataEC50:  520nMAssay Description:The effective concentration in CV-1 cells for glucocorticoid response element activation (GRE).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM50107365(5-Cyclohexyl-10-methoxy-2,2,4-trimethyl-2,5-dihydr...)
Affinity DataEC50:  5.00E+3nMAssay Description:The effective concentration in CV-1 cells for glucocorticoid response element activation (GRE).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM50107360(2-(10-Methoxy-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa...)
Affinity DataEC50: >5.00E+3nMAssay Description:Effective concentration in HepG2 cells transfected with LUC gene (E-sel-Luc).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM50107351(2-(10-Methoxy-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa...)
Affinity DataEC50: >5.00E+3nMAssay Description:Effective concentration in HepG2 cells transfected with LUC gene (E-sel-Luc).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM50107360(2-(10-Methoxy-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa...)
Affinity DataEC50: >5.00E+3nMAssay Description:The effective concentration in CV-1 cells for glucocorticoid response element activation (GRE).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM50219260(5-(3-cyclopentyl-2-thioxo-2,3-dihydro-1H-benzimida...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at glucocorticoid receptor expressed in L929 cells by HRE-tk luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM50124605(5-Allyl-7-bromo-10-methoxy-2,2,4-trimethyl-2,5-dih...)
Affinity DataEC50:  59nMAssay Description:Transcriptional repression in HepG2 cells expressing human glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM50124597(5-Allyl-10-difluoromethoxy-2,2,4-trimethyl-2,5-dih...)
Affinity DataEC50:  563nMAssay Description:Inhibition of concanavalin A stimulated T-cell proliferation in human PBMCsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM50124596(5-Allyl-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza...)
Affinity DataEC50:  550nMAssay Description:Transcriptional activation in CV-1 cells expressing human glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM50124615(5-Allyl-10-ethynyl-2,2,4-trimethyl-2,5-dihydro-1H-...)
Affinity DataEC50:  130nMAssay Description:Transcriptional activation in CV-1 cells expressing human glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM50124597(5-Allyl-10-difluoromethoxy-2,2,4-trimethyl-2,5-dih...)
Affinity DataEC50:  35nMAssay Description:Transcriptional activation in CV-1 cells expressing human glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM50124593(5-Allyl-2,2,4-trimethyl-10-methylsulfanyl-2,5-dihy...)
Affinity DataEC50:  123nMAssay Description:Transcriptional activation in CV-1 cells expressing human glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM50124621(5-Allyl-10-methoxy-2,2,4,7-tetramethyl-2,5-dihydro...)
Affinity DataEC50:  81nMAssay Description:Transcriptional repression in HepG2 cells expressing human glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM50124594((5-Allyl-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-az...)
Affinity DataEC50:  19nMAssay Description:Transcriptional repression in HepG2 cells expressing human glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM50107347(5-Allyl-10-methoxy-2,2,4-trimethyl-2,5-dihydro-1H-...)
Affinity DataEC50:  13nMAssay Description:Transcriptional repression in HepG2 cells expressing human glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM50124619(5-Allyl-10-methoxy-2,2,4-trimethyl-2,5-dihydro-1H-...)
Affinity DataEC50:  14nMAssay Description:Transcriptional repression in HepG2 cells expressing human glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM50124613(5-Allyl-9,10-dimethoxy-2,2,4-trimethyl-2,5-dihydro...)
Affinity DataEC50:  120nMAssay Description:Transcriptional repression in HepG2 cells expressing human glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM50124602((5-Allyl-10-methoxy-2,2,4-trimethyl-2,5-dihydro-1H...)
Affinity DataEC50:  130nMAssay Description:Transcriptional repression in HepG2 cells expressing human glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM50124606(5-Allyl-2,2,4-trimethyl-10-vinyl-2,5-dihydro-1H-6-...)
Affinity DataEC50:  12nMAssay Description:Transcriptional repression in HepG2 cells expressing human glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM50124601(5-Allyl-10-methoxymethyl-2,2,4-trimethyl-2,5-dihyd...)
Affinity DataEC50:  305nMAssay Description:Transcriptional repression in HepG2 cells expressing human glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM50124604(5-Allyl-9-fluoro-10-methoxy-2,2,4-trimethyl-2,5-di...)
Affinity DataEC50:  81nMAssay Description:Transcriptional repression in HepG2 cells expressing human glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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