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Report error Found 109 Enz. Inhib. hit(s) with Target = 'Gamma-aminobutyric acid receptor subunit rho-1'
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50087271(4-Amino-but-2-enoic acid | (E)-4-Amino-but-2-enoic...)
Affinity DataEC50:  440nMAssay Description:Partial agonist activity against human rho-1 subunit GABA-C receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50087269((trans)-2-Aminomethyl-cyclopropanecarboxylic acid ...)
Affinity DataEC50:  6.80E+4nMAssay Description:Full agonist activity against human rho-1 subunit GABA-C receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM24183(4-amino-n-[2,3-3H]butyric acid | cid_119 | Gamma-A...)
Affinity DataEC50:  270nMAssay Description:Agonist activity at human GABAA rho1 expressed in tsA-201cells by FLIPR membrane potential blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50052792(CHEBI:7035 | Muscimol)
Affinity DataEC50:  700nMAssay Description:Agonist activity at human GABAA rho1 expressed in tsA-201cells by FLIPR membrane potential blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50032955(1,2,3,6-Tetrahydro-pyridine-4-carboxylic acid | CH...)
Affinity DataEC50:  3.90E+4nMAssay Description:Agonist activity at human GABAA rho1 expressed in tsA-201cells by FLIPR membrane potential blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50052794(CHEMBL3322871)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonist activity at human GABAA rho1 expressed in tsA-201cells by FLIPR membrane potential blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50052795(CHEMBL3322872)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonist activity at human GABAA rho1 expressed in tsA-201cells by FLIPR membrane potential blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50052797(CHEMBL3322876)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonist activity at human GABAA rho1 expressed in tsA-201cells by FLIPR membrane potential blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50052798(CHEMBL3322877)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonist activity at human GABAA rho1 expressed in tsA-201cells by FLIPR membrane potential blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50052799(CHEMBL3322882)
Affinity DataEC50:  2.30E+3nMAssay Description:Agonist activity at human GABAA rho1 expressed in tsA-201cells by FLIPR membrane potential blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50052801(CHEMBL3322886)
Affinity DataEC50:  8.10E+3nMAssay Description:Agonist activity at human GABAA rho1 expressed in tsA-201cells by FLIPR membrane potential blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM24183(4-amino-n-[2,3-3H]butyric acid | cid_119 | Gamma-A...)
Affinity DataEC50:  269nMAssay Description:Agonist activity at human GABAA rho1 expressed in tsA-201cells by FLIPR membrane potential blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50052792(CHEBI:7035 | Muscimol)
Affinity DataEC50:  692nMAssay Description:Agonist activity at human GABAA rho1 expressed in tsA-201cells by FLIPR membrane potential blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50032955(1,2,3,6-Tetrahydro-pyridine-4-carboxylic acid | CH...)
Affinity DataEC50:  3.89E+4nMAssay Description:Agonist activity at human GABAA rho1 expressed in tsA-201cells by FLIPR membrane potential blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50052794(CHEMBL3322871)
Affinity DataEC50: <1.00E+6nMAssay Description:Agonist activity at human GABAA rho1 expressed in tsA-201cells by FLIPR membrane potential blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50052795(CHEMBL3322872)
Affinity DataEC50: <1.00E+6nMAssay Description:Agonist activity at human GABAA rho1 expressed in tsA-201cells by FLIPR membrane potential blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50052797(CHEMBL3322876)
Affinity DataEC50: <1.00E+6nMAssay Description:Agonist activity at human GABAA rho1 expressed in tsA-201cells by FLIPR membrane potential blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50052798(CHEMBL3322877)
Affinity DataEC50: <1.00E+6nMAssay Description:Agonist activity at human GABAA rho1 expressed in tsA-201cells by FLIPR membrane potential blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50052799(CHEMBL3322882)
Affinity DataEC50:  2.30E+3nMAssay Description:Agonist activity at human GABAA rho1 expressed in tsA-201cells by FLIPR membrane potential blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50052801(CHEMBL3322886)
Affinity DataEC50:  8.10E+3nMAssay Description:Agonist activity at human GABAA rho1 expressed in tsA-201cells by FLIPR membrane potential blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50243877((1R,2S)-2-(aminomethyl)cyclopropanecarboxylic acid...)
Affinity DataEC50:  4.00E+4nMAssay Description:Agonist activity at human GABAc Rho1 receptor expressed in Xenopus oocytes assessed as whole cell current production by two electrode voltage clamp m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50087271(4-Amino-but-2-enoic acid | (E)-4-Amino-but-2-enoic...)
Affinity DataEC50:  400nMAssay Description:Agonist activity at human GABAc Rho1 receptor expressed in Xenopus oocytes assessed as whole cell current production by two electrode voltage clamp m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM23183(CHEMBL273481 | Muscimol | 5-(aminomethyl)-1,2-oxaz...)
Affinity DataEC50:  1.40E+3nMAssay Description:Agonist activity at human GABAc Rho1 receptor expressed in Xenopus oocytes assessed as whole cell current production by two electrode voltage clamp m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50243927((1S,2S)-2-(aminomethyl)cyclopropanecarboxylic acid...)
Affinity DataEC50:  5.90E+4nMAssay Description:Agonist activity at human GABAc Rho1 receptor expressed in Xenopus oocytes assessed as whole cell current production by two electrode voltage clamp m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50243926((1R,2R)-2-(aminomethyl)cyclopropanecarboxylic acid...)
Affinity DataEC50:  9.00E+3nMAssay Description:Agonist activity at human GABAc Rho1 receptor expressed in Xenopus oocytes assessed as whole cell current production by two electrode voltage clamp m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM24183(4-amino-n-[2,3-3H]butyric acid | cid_119 | Gamma-A...)
Affinity DataEC50:  800nMAssay Description:Agonist activity at human GABAc Rho1 receptor expressed in Xenopus oocytes assessed as whole cell current production by two electrode voltage clamp m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50087277(4-aminobut-2-enoic acid | (Z)-4-aminobut-2-enoic a...)
Affinity DataEC50:  7.40E+4nMAssay Description:Agonist activity at human GABAc Rho1 receptor expressed in Xenopus oocytes assessed as whole cell current production by two electrode voltage clamp m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM23183(CHEMBL273481 | Muscimol | 5-(aminomethyl)-1,2-oxaz...)
Affinity DataKd:  2.30E+3nMAssay Description:Partial agonist activity against human rho-1 subunit GABA-C receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50087271(4-Amino-but-2-enoic acid | (E)-4-Amino-but-2-enoic...)
Affinity DataEC50:  600nMAssay Description:Partial agonist activity against homomeric rho-1 subunit GABA-C receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50087269((trans)-2-Aminomethyl-cyclopropanecarboxylic acid ...)
Affinity DataEC50:  2.00E+4nMAssay Description:Full agonist activity against human rho-1 subunit GABA-C receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50087273(4-Amino-2-fluoro-but-2-enoic acid (2-FTACA) | CHEM...)
Affinity DataEC50:  2.43E+3nMAssay Description:Partial agonist activity against rho-1 subunit GABA-C receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM85712(1H-imidazol-4-ylacetic acid | NSC_96215 | CAS_645-...)
Affinity DataEC50:  1.60E+4nMAssay Description:Partial agonist activity against rho-1 subunit GABA-C receptor expressed in Xenopus oocytes, low intrinsic activity (Im 3%)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50087276(3-Amino-propane-1-sulfinic acid (Homohypotaurine) ...)
Affinity DataEC50:  4.60E+3nMAssay Description:Partial agonist activity against human rho-1 subunit GABA-C receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50087277(4-aminobut-2-enoic acid | (Z)-4-aminobut-2-enoic a...)
Affinity DataEC50:  7.40E+4nMAssay Description:Partial agonist activity against human rho-1 subunit GABA-C receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50425640(CHEMBL2315226)
Affinity DataEC50: >5.00E+5nMAssay Description:Agonist activity at human GABAA rho1 receptor expressed in TSA201 cells after 1 min by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50425641(CHEMBL2311576)
Affinity DataEC50: >5.00E+5nMAssay Description:Agonist activity at human GABAA rho1 receptor expressed in TSA201 cells after 1 min by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50425642(CHEMBL2315222)
Affinity DataEC50: >5.00E+5nMAssay Description:Agonist activity at human GABAA rho1 receptor expressed in TSA201 cells after 1 min by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50425643(CHEMBL2315220)
Affinity DataEC50: >5.00E+5nMAssay Description:Agonist activity at human GABAA rho1 receptor expressed in TSA201 cells after 1 min by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50425644(CHEMBL2315218)
Affinity DataEC50: >5.00E+5nMAssay Description:Agonist activity at human GABAA rho1 receptor expressed in TSA201 cells after 1 min by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50425645(CHEMBL2315216)
Affinity DataEC50: >5.00E+5nMAssay Description:Agonist activity at human GABAA rho1 receptor expressed in TSA201 cells after 1 min by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50425646(CHEMBL2315214)
Affinity DataEC50: >5.00E+5nMAssay Description:Agonist activity at human GABAA rho1 receptor expressed in TSA201 cells after 1 min by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50425647(CHEMBL2315213)
Affinity DataEC50:  3.10E+3nMAssay Description:Agonist activity at human GABAA rho1 receptor expressed in TSA201 cells after 1 min by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM23183(CHEMBL273481 | Muscimol | 5-(aminomethyl)-1,2-oxaz...)
Affinity DataEC50:  700nMAssay Description:Agonist activity at human GABAA rho1 receptor expressed in TSA201 cells after 1 min by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM24183(4-amino-n-[2,3-3H]butyric acid | cid_119 | Gamma-A...)
Affinity DataEC50:  270nMAssay Description:Agonist activity at human GABAA rho1 receptor expressed in TSA201 cells after 1 min by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50425647(CHEMBL2315213)
Affinity DataEC50:  5.50E+4nMAssay Description:Agonist activity at human GABAA rho1 receptor expressed in HEK293 cells by patch clamp electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM23183(CHEMBL273481 | Muscimol | 5-(aminomethyl)-1,2-oxaz...)
Affinity DataEC50:  2.30E+3nMAssay Description:Partial agonist activity at GABAC rho1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50218536(4(5)-(carboxymethyl)-5(4)-methylimidazole | CHEMBL...)
Affinity DataEC50:  2.20E+4nMAssay Description:Agonist activity at GABAC rho1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50241194((1S,2R)-2-aminomethyl-cyclopropanecarboxylic acid ...)
Affinity DataEC50:  3.97E+4nMAssay Description:Agonist activity at GABAC rho1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM24183(4-amino-n-[2,3-3H]butyric acid | cid_119 | Gamma-A...)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at GABAC rho1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50374647(CHEMBL256608)
Affinity DataEC50:  6.50E+4nMAssay Description:Agonist activity at human recombinant GABAc rho1 receptor expressed in Xenopus laevis oocytes at -60mV by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
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