Compile Data Set for Download or QSAR
Report error Found 64 Enz. Inhib. hit(s) with Target = 'Gamma-aminobutyric acid receptor subunit alpha-6/beta-2'
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/delta(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50457445(CHEMBL4212818)
Affinity DataEC50:  2.29E+3nMAssay Description:Modulation of rat eGFP-fused GABA-A receptor alpha6beta3delta expressed in HEK293 cells in presence of GABA by patch-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/delta(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50457439(CHEMBL4213357)
Affinity DataEC50:  130nMAssay Description:Modulation of rat eGFP-fused GABA-A receptor alpha6beta3delta expressed in HEK293 cells in presence of GABA by patch-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/delta(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50457439(CHEMBL4213357)
Affinity DataIC50: 150nMAssay Description:Displacement of [3H]EBOB from rat GABA-A receptor alpha6beta2delta expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/delta(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50457444(CHEMBL4213793)
Affinity DataIC50: 270nMAssay Description:Displacement of [3H]EBOB from rat GABA-A receptor alpha6beta2delta expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50457439(CHEMBL4213357)
Affinity DataIC50: 630nMAssay Description:Displacement of [3H]EBOB from rat GABA-A receptor alpha6beta2 expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50457444(CHEMBL4213793)
Affinity DataIC50: 740nMAssay Description:Displacement of [3H]EBOB from rat GABA-A receptor alpha6beta2 expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50457439(CHEMBL4213357)
Affinity DataIC50: 1.13E+3nMAssay Description:Displacement of [3H]EBOB from rat GABA-A receptor alpha6beta2gamma2 expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/delta(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50457438(CHEMBL4208971)
Affinity DataIC50: 2.43E+3nMAssay Description:Displacement of [3H]EBOB from rat GABA-A receptor alpha6beta2delta expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50000766(CHEMBL12 | DIAZEPAM | US9271961, Diazepam)
Affinity DataKi:  2.10nMAssay Description:Binding affinity for mutant rat GABA-A receptor alpha-6-(his,thr,gly,val)beta2gamma2 subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM26267(RO-154513 | Ro15-4513 | ethyl 12-azido-8-methyl-9-...)
Affinity DataKi:  3.80nMAssay Description:Binding affinity for human GABA-A receptor alpha-6-beta-2-gamma-2 expressed in L(tk-) cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50049736(8-Ethynyl-5-methyl-6-oxo-5,6-dihydro-4H-2,5,10b-tr...)
Affinity DataKi:  5.10nMAssay Description:Binding affinity for human GABA-A receptor alpha-6-beta-2-gamma-2 expressed in L(tk-) cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM26267(RO-154513 | Ro15-4513 | ethyl 12-azido-8-methyl-9-...)
Affinity DataKi:  5.40nMAssay Description:Displacement of [3H]Ro-154513 from GABA-A receptor alpha-6-beta-2-gamma-2 subunits expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM26267(RO-154513 | Ro15-4513 | ethyl 12-azido-8-methyl-9-...)
Affinity DataKi:  5.40nMAssay Description:Displacement of [3H]-Ro- 15-4513 from alpha-6-beta-2-gamma-2 GABA-A receptor subunits expressed in Sf9 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50001478(9H-beta-Carboline-3-carboxylic acid methyl ester |...)
Affinity DataKi:  6nMAssay Description:Binding affinity for mutant rat GABA-A receptor alpha-6-(his,thr)beta2gamma2 subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50001478(9H-beta-Carboline-3-carboxylic acid methyl ester |...)
Affinity DataKi:  8nMAssay Description:Binding affinity for mutant rat GABA-A receptor alpha-6-(his,thr,gly)beta2gamma2 subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50035527(3-Methyl-9H-beta-carboline | CHEMBL344859)
Affinity DataKi:  8nMAssay Description:Binding affinity for mutant rat GABA-A receptor alpha-6-(his,thr,gly)beta2gamma2 subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50000766(CHEMBL12 | DIAZEPAM | US9271961, Diazepam)
Affinity DataKi:  9nMAssay Description:Binding affinity for mutant rat GABA-A receptor alpha-6-(his,thr,gly)beta2gamma2 subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50044947(8-Bromo-5-methyl-6-oxo-5,6-dihydro-4H-2,5,10b-tria...)
Affinity DataKi:  9.40nMAssay Description:Binding affinity for human GABA-A receptor alpha-6-beta-2-gamma-2 expressed in L(tk-) cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50001478(9H-beta-Carboline-3-carboxylic acid methyl ester |...)
Affinity DataKi:  10nMAssay Description:Binding affinity for rat GABA-A receptor alpha-6-beta-2-gamma-2 subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50035527(3-Methyl-9H-beta-carboline | CHEMBL344859)
Affinity DataKi:  11nMAssay Description:Binding affinity for mutant rat GABA-A receptor alpha-6-(his,thr,gly,val)beta2gamma2 subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50048831([3-(5-Cyclopropyl-[1,2,4]oxadiazol-3-yl)-6-fluoro-...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]-Ro-15-4513 from GABA-A receptor alpha-6-beta-2-gamma-2 subunits expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50048855(3-(5-Cyclopropyl-[1,2,4]oxadiazol-3-yl)-4H-imidazo...)
Affinity DataKi:  13.2nMAssay Description:Displacement of [3H]-Ro- 15-4513 from alpha-6 beta2 gamma2 subunits of Rat GABA-A receptor expressed in Sf-9 insect cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM26263(ethyl 12-fluoro-8-methyl-9-oxo-2,4,8-triazatricycl...)
Affinity DataKi:  15nMAssay Description:Binding affinity for mutant rat GABA-A receptor alpha-6-(his,thr,gly)beta2gamma2 subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM26263(ethyl 12-fluoro-8-methyl-9-oxo-2,4,8-triazatricycl...)
Affinity DataKi:  17nMAssay Description:Binding affinity for mutant rat GABA-A receptor alpha-6-(his)-beta-2-gamma-2 subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM26263(ethyl 12-fluoro-8-methyl-9-oxo-2,4,8-triazatricycl...)
Affinity DataKi:  17nMAssay Description:Binding affinity for mutant rat GABA-A receptor alpha-6-(his,thr)beta2gamma2 subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50000766(CHEMBL12 | DIAZEPAM | US9271961, Diazepam)
Affinity DataKi:  20nMAssay Description:Binding affinity for mutant rat GABA-A receptor alpha-6-(his,thr)beta2gamma2 subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50049739(DM 286 | CHEMBL58570 | 8-Ethyl-5-methyl-6-oxo-5,6-...)
Affinity DataKi:  23nMAssay Description:Binding affinity for human GABA-A receptor alpha-6-beta-2-gamma-2 expressed in L(tk-) cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM25877(CHEMBL286594 | ethyl 12-ethynyl-8-methyl-9-oxo-2,4...)
Affinity DataKi:  29nMAssay Description:Binding affinity for human GABA-A receptor alpha-6-beta-2-gamma-2 expressed in L(tk-) cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM26263(ethyl 12-fluoro-8-methyl-9-oxo-2,4,8-triazatricycl...)
Affinity DataKi:  33nMAssay Description:Binding affinity for mutant rat GABA-A receptor alpha-6-(his,thr,gly,val)beta2gamma2 subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50035527(3-Methyl-9H-beta-carboline | CHEMBL344859)
Affinity DataKi:  39nMAssay Description:Binding affinity for mutant rat GABA-A receptor alpha-6-(his,thr)beta2gamma2 subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50049737(5-Methyl-6-oxo-8-propa-1,2-dienyl-5,6-dihydro-4H-2...)
Affinity DataKi:  44nMAssay Description:Binding affinity for human GABA-A receptor alpha-6-beta-2-gamma-2 expressed in L(tk-) cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50035527(3-Methyl-9H-beta-carboline | CHEMBL344859)
Affinity DataKi:  45nMAssay Description:Binding affinity for mutant rat GABA-A receptor alpha-6-(his)-beta-2-gamma-2 subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50049735(CHEMBL300840 | RY 24 | 5-Methyl-6-oxo-8-trimethyls...)
Affinity DataKi:  59nMAssay Description:Binding affinity for human GABA-A receptor alpha-6-beta-2-gamma-2 expressed in L(tk-) cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM26263(ethyl 12-fluoro-8-methyl-9-oxo-2,4,8-triazatricycl...)
Affinity DataKi:  90nMAssay Description:Binding affinity for rat GABA-A receptor alpha-6-beta-2-gamma-2 subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50000766(CHEMBL12 | DIAZEPAM | US9271961, Diazepam)
Affinity DataKi:  98nMAssay Description:Binding affinity for mutant rat GABA-A receptor alpha-6-(his)-beta-2-gamma-2 subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50049740(5-Methyl-6-oxo-8-prop-1-ynyl-5,6-dihydro-4H-2,5,10...)
Affinity DataKi: >100nMAssay Description:Binding affinity for human GABA-A receptor alpha-6-beta-2-gamma-2 expressed in L(tk-) cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50049738(5-Methyl-6-oxo-8-trimethylsilanylethynyl-5,6-dihyd...)
Affinity DataKi:  114nMAssay Description:Binding affinity for human GABA-A receptor alpha-6-beta-2-gamma-2 expressed in L(tk-) cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50040722(1-[3-(5-Cyclopropyl-[1,2,4]oxadiazol-3-yl)-4H-imid...)
Affinity DataKi:  124nMAssay Description:Displacement of [3H]Ro-154513 from GABA-A receptor alpha-6-beta-2-gamma-2 subunits expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50049734(8-Ethyl-5-methyl-6-oxo-5,6-dihydro-4H-2,5,10b-tria...)
Affinity DataKi:  176nMAssay Description:Binding affinity for human GABA-A receptor alpha-6-beta-2-gamma-2 expressed in L(tk-) cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50001478(9H-beta-Carboline-3-carboxylic acid methyl ester |...)
Affinity DataKi:  190nMAssay Description:Binding affinity for mutant rat GABA-A receptor alpha-6-(his,thr,gly,val)beta2gamma2 subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50049733(5-Methyl-6-oxo-8-(3-trimethylsilanyl-prop-1-ynyl)-...)
Affinity DataKi: >300nMAssay Description:Binding affinity for human GABA-A receptor alpha-6-beta-2-gamma-2 expressed in L(tk-) cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50054656(8-(5-Cyclopropyl-[1,2,4]oxadiazol-3-yl)-5-isopropy...)
Affinity DataKi: >589nMAssay Description:Displacement of [3H]-Ro- 15-4513 from alpha-6 beta2 gamma2 subunits of Rat GABA-A receptor expressed in Sf-9 insect cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50054660(8-(5-Cyclopropyl-[1,2,4]oxadiazol-3-yl)-4,5-dihydr...)
Affinity DataKi: >589nMAssay Description:Displacement of [3H]-Ro- 15-4513 from alpha-6 beta2 gamma2 subunits of Rat GABA-A receptor expressed in Sf-9 insect cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50054659(8-(5-Cyclopropyl-[1,2,4]oxadiazol-3-yl)-4H,7H-5-ox...)
Affinity DataKi: >589nMAssay Description:Displacement of [3H]-Ro- 15-4513 from alpha-6 beta2 gamma2 subunits of Rat GABA-A receptor expressed in Sf-9 insect cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50054662(8-(5-Cyclopropyl-[1,2,4]oxadiazol-3-yl)-4,4-dimeth...)
Affinity DataKi: >589nMAssay Description:Displacement of [3H]-Ro- 15-4513 from alpha-6 beta2 gamma2 subunits of Rat GABA-A receptor expressed in Sf-9 insect cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50054663(7-(5-Cyclopropyl-[1,2,4]oxadiazol-3-yl)-4-methoxy-...)
Affinity DataKi: >589nMAssay Description:Displacement of [3H]-Ro- 15-4513 from alpha-6 beta2 gamma2 subunits of Rat GABA-A receptor expressed in Sf-9 insect cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50054661(8-(5-Cyclopropyl-[1,2,4]oxadiazol-3-yl)-5-methyl-4...)
Affinity DataKi: >589nMAssay Description:Displacement of [3H]-Ro- 15-4513 from alpha-6 beta2 gamma2 subunits of Rat GABA-A receptor expressed in Sf-9 insect cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50048837(Panadiplon | U-78875 | 3-(5-Cyclopropyl-[1,2,4]oxa...)
Affinity DataKi:  603nMAssay Description:Displacement of [3H]-Ro-15-4513 from GABA-A receptor alpha-6-beta-2-gamma-2 subunits expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50026756(CHEMBL13662 | CL 218872 | 3-Methyl-6-(3-trifluorom...)
Affinity DataKi:  620nMAssay Description:Binding affinity for mutant rat GABA-A receptor alpha-6-(his,thr,gly)beta2gamma2 subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50026756(CHEMBL13662 | CL 218872 | 3-Methyl-6-(3-trifluorom...)
Affinity DataKi:  780nMAssay Description:Binding affinity for mutant rat GABA-A receptor alpha-6-(his,thr,gly,val)beta2gamma2 subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
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