Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with Target = 'GMP synthase [glutamine-hydrolyzing]'
TargetGMP synthase [glutamine-hydrolyzing](Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  173nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetGMP synthase [glutamine-hydrolyzing](Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM724945(US12240821, Compound 1)
Affinity DataIC50: 6.20nMAssay Description:The potency of the five compounds was tested against recombinant GMPS in an enzymatic assay by monitoring UV absorbance at 290 nm and by determining ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/3/2025
Entry Details
Go to US Patent

TargetGMP synthase [glutamine-hydrolyzing](Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM724946(US12240821, Compound 2)
Affinity DataIC50: 23nMAssay Description:The potency of the five compounds was tested against recombinant GMPS in an enzymatic assay by monitoring UV absorbance at 290 nm and by determining ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/3/2025
Entry Details
Go to US Patent

TargetGMP synthase [glutamine-hydrolyzing](Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM724948(US12240821, Compound 4)
Affinity DataIC50: 98nMAssay Description:The potency of the five compounds was tested against recombinant GMPS in an enzymatic assay by monitoring UV absorbance at 290 nm and by determining ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/3/2025
Entry Details
Go to US Patent

TargetGMP synthase [glutamine-hydrolyzing](Mouse)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50042853(N-(4-Isothiocyanatomethyl-thiazol-2-yl)-benzamide ...)
Affinity DataIC50: 350nMAssay Description:In vitro inhibitory activity against partially purified GMP synthetase in L1210 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGMP synthase [glutamine-hydrolyzing](Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM724947(US12240821, Compound 3)
Affinity DataIC50: 1.00E+3nMAssay Description:The potency of the five compounds was tested against recombinant GMPS in an enzymatic assay by monitoring UV absorbance at 290 nm and by determining ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/3/2025
Entry Details
Go to US Patent

TargetGMP synthase [glutamine-hydrolyzing](Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM724949(US12240821, Compound 5)
Affinity DataIC50: 1.00E+3nMAssay Description:The potency of the five compounds was tested against recombinant GMPS in an enzymatic assay by monitoring UV absorbance at 290 nm and by determining ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/3/2025
Entry Details
Go to US Patent

TargetGMP synthase [glutamine-hydrolyzing](Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50519499(CHEBI:8612 | Psicofuranine)
Affinity DataIC50: 1.73E+4nMAssay Description:Inhibition of human GMP synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetGMP synthase [glutamine-hydrolyzing](Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50519498(Decoyinine)
Affinity DataIC50: 4.65E+4nMAssay Description:Inhibition of human GMP synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed