Compile Data Set for Download or QSAR
Report error Found 46 Enz. Inhib. hit(s) with Target = 'Fatty acid synthase [2202-2509]'
TargetFatty acid synthase [2202-2509](Human)
Texas A&M University

LigandPNGBDBM24972((2S)-1-[(2S,3S)-3-hexyl-4-oxoazetidin-2-yl]trideca...)
Affinity DatapH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
Texas A&M University

LigandPNGBDBM24973((2R)-1-[(2R,3R)-3-hexyl-4-oxoazetidin-2-yl]trideca...)
Affinity DatapH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
Texas A&M University

LigandPNGBDBM24974((2S)-1-[(2S,3S)-3-hexyl-4-oxoazetidin-2-yl]heptan-...)
Affinity DatapH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
Texas A&M University

LigandPNGBDBM24572((2R)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]heptan-2-...)
Affinity DataIC50: 100nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
Texas A&M University

LigandPNGBDBM24573((2S,5E)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridec...)
Affinity DataIC50: 120nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
Texas A&M University

LigandPNGBDBM24574((2R)-1-[(2S,3R)-3-hexyl-4-oxooxetan-2-yl]tridecan-...)
Affinity DataIC50: 180nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
Texas A&M University

LigandPNGBDBM24575((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]pentadeca...)
Affinity DataIC50: 210nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
Texas A&M University

LigandPNGBDBM24569(Orlistat derivative, 15f | (2S)-1-[(2S,3S)-3-ethyl...)
Affinity DataIC50: 230nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
Texas A&M University

LigandPNGBDBM24570((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]hex-5-en-...)
Affinity DataIC50: 280nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
Texas A&M University

LigandPNGBDBM24576((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]pentadeca...)
Affinity DataIC50: 290nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
Texas A&M University

LigandPNGBDBM24571((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]heptan-2-...)
Affinity DataIC50: 300nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
Texas A&M University

LigandPNGBDBM24577((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]-3-{[(4-m...)
Affinity DataIC50: 370nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
Texas A&M University

LigandPNGBDBM24578((2S,5E)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridec...)
Affinity DataIC50: 400nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
Texas A&M University

LigandPNGBDBM24579((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]pentadeca...)
Affinity DataIC50: 450nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
Texas A&M University

LigandPNGBDBM24580((2S,5E)-6-(4-fluorophenyl)-1-[(2S,3S)-3-hexyl-4-ox...)
Affinity DataIC50: 500nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
Texas A&M University

LigandPNGBDBM24581((2R)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]hex-5-en-...)
Affinity DataIC50: 500nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
Texas A&M University

LigandPNGBDBM24582((2R)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]propan-2-...)
Affinity DataIC50: 520nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
Texas A&M University

LigandPNGBDBM24583((2R,5E)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]hept-5...)
Affinity DataIC50: 680nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
Texas A&M University

LigandPNGBDBM24569(Orlistat derivative, 15f | (2S)-1-[(2S,3S)-3-ethyl...)
Affinity DataIC50: 790nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
Texas A&M University

LigandPNGBDBM24585((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]hex-5-en-...)
Affinity DataIC50: 900nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
Texas A&M University

LigandPNGBDBM24586((1R)-1-{[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]methyl}d...)
Affinity DataIC50: 1.02E+3nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
Texas A&M University

LigandPNGBDBM24587((2S,5E)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]hept-5...)
Affinity DataIC50: 1.04E+3nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
Texas A&M University

LigandPNGBDBM24588((1R)-1-{[(2S,3S)-3-butyl-4-oxooxetan-2-yl]methyl}d...)
Affinity DataIC50: 1.35E+3nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
Texas A&M University

LigandPNGBDBM24567(Tetrahydrolipstatin | CHEMBL175247 | Xenical | (2S...)
Affinity DataIC50: 1.35E+3nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
Texas A&M University

LigandPNGBDBM24586((1R)-1-{[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]methyl}d...)
Affinity DataIC50: 1.72E+3nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
Texas A&M University

LigandPNGBDBM24590((2S)-1-[(2S,3S)-3-octyl-4-oxooxetan-2-yl]undecan-2...)
Affinity DataIC50: 3.00E+3nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
Texas A&M University

LigandPNGBDBM24591((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]pentadeca...)
Affinity DataIC50: 3.67E+3nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
Texas A&M University

LigandPNGBDBM24592((2R,5E)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]hept-5...)
Affinity DataIC50: 6.24E+3nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
Texas A&M University

LigandPNGBDBM24975((3S,4S)-1-(benzyloxy)-4-[(2S)-2-[(tert-butyldimeth...)
Affinity DataIC50: 8.60E+3nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
Texas A&M University

LigandPNGBDBM24593((2S)-1-[(2R,3R)-3-hexyl-4-oxooxetan-2-yl]pentadeca...)
Affinity DataIC50: 9.74E+3nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
Texas A&M University

LigandPNGBDBM24594((2S)-1-[(2S,3S)-3-methyl-4-oxooxetan-2-yl]tridecan...)
Affinity DataIC50: 1.08E+4nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
Texas A&M University

LigandPNGBDBM24595((2S,5E)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]hept-5...)
Affinity DataIC50: 1.35E+4nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
Texas A&M University

LigandPNGBDBM24980((2R)-1-[(2R,3R)-1-(benzyloxy)-3-hexyl-4-oxoazetidi...)
Affinity DataIC50: 3.92E+4nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
Texas A&M University

LigandPNGBDBM24596((2S)-1-[(2R,3R)-3-methyl-4-oxooxetan-2-yl]tridecan...)
Affinity DataIC50: 4.51E+4nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
Texas A&M University

LigandPNGBDBM24981((3S,4S)-1-(benzyloxy)-3-hexyl-4-[(2S)-2-hydroxyhep...)
Affinity DataIC50: 5.05E+4nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
Texas A&M University

LigandPNGBDBM24982((2S)-1-[(2S,3S)-1-(benzyloxy)-3-hexyl-4-oxoazetidi...)
Affinity DataIC50: 5.82E+4nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
Texas A&M University

LigandPNGBDBM24978((3R,4R)-1-(benzyloxy)-3-hexyl-4-[(2R)-2-hydroxytri...)
Affinity DataIC50: 6.12E+4nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
Texas A&M University

LigandPNGBDBM24983((3S,4S)-3-hexyl-4-[(2S)-2-hydroxyheptyl]azetidin-2...)
Affinity DataIC50: 6.76E+4nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
Texas A&M University

LigandPNGBDBM24979((2S)-1-[(2S,3S)-1-(benzyloxy)-3-hexyl-4-oxoazetidi...)
Affinity DataIC50: 6.89E+4nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
Texas A&M University

LigandPNGBDBM24977((3S,4S)-1-(benzyloxy)-3-hexyl-4-[(2S)-2-hydroxytri...)
Affinity DataIC50: 8.68E+4nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
Texas A&M University

LigandPNGBDBM24976((3R,4R)-1-(benzyloxy)-4-[(2R)-2-[(tert-butyldimeth...)
Affinity DataIC50: 9.74E+4nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
Texas A&M University

LigandPNGBDBM24988(1-(3-hexyl-4-oxooxetan-2-yl)tridecan-2-yl 2-formam...)
Affinity DataKi:  300nM ΔG°:  -38.7kJ/molepH: 7.5 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
Texas A&M University

LigandPNGBDBM24984((5E)-1-(3,5-dimethylphenyl)-5-[(5-phenylfuran-2-yl...)
Affinity DataKi:  380nM ΔG°:  -38.1kJ/molepH: 7.5 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
Texas A&M University

LigandPNGBDBM24987((5E)-1-benzyl-5-{[5-(2-chlorophenyl)furan-2-yl]met...)
Affinity DataKi:  850nM ΔG°:  -36.0kJ/molepH: 7.5 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
Texas A&M University

LigandPNGBDBM24986((5E)-1-(3-bromophenyl)-5-{[5-(2-nitrophenyl)furan-...)
Affinity DataKi:  880nM ΔG°:  -36.0kJ/molepH: 7.5 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
Texas A&M University

LigandPNGBDBM24985((5E)-5-{[5-(4-fluorophenyl)furan-2-yl]methylidene}...)
Affinity DataKi:  910nM ΔG°:  -35.9kJ/molepH: 7.5 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2008
Entry Details Article
PubMed