Compile Data Set for Download or QSAR
Report error Found 492 Enz. Inhib. hit(s) with Target = 'E-selectin'
TargetE-selectin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50450369(Sialyl LeX | Sialyl lewis-x | sLex | sialyl LewisX...)
Affinity DataKd:  1.00E+6nMAssay Description:Ability to inhibit the binding to Selectin E immobilized on SPA beads of radiolabeled HL-60 cell membrane was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetE-selectin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50646324(CHEMBL5593432)
Affinity DataKd:  7.38E+5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE-selectin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50646325(Rivipansel | GMI-1070 | PF-06460031)
Affinity DataKd:  4.30E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE-selectin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50646326(CHEMBL5592209)
Affinity DataKd:  2.63E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE-selectin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50646327(CHEMBL5592583)
Affinity DataKd:  1.90E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE-selectin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50646328(CHEMBL5593230)
Affinity DataKd:  1.15E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE-selectin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50646329(CHEMBL5590365)
Affinity DataKd:  910nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE-selectin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50646330(CHEMBL5594959)
Affinity DataKd:  1.38E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE-selectin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50646327(CHEMBL5592583)
Affinity DataKd:  1.90E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE-selectin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50646329(CHEMBL5590365)
Affinity DataKd:  740nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE-selectin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50646331(CHEMBL407747)
Affinity DataKd:  6.07E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE-selectin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50646332(CHEMBL5594888)
Affinity DataKd:  1.78E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE-selectin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50646333(CHEMBL5595169)
Affinity DataKd:  8.40E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE-selectin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50105186(4-(4-Trifluoromethyl-phenoxy)-thieno[2,3-c]pyridin...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of selectin E in human endothelial cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetE-selectin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50105151(4-(4-Vinyl-phenoxy)-thieno[2,3-c]pyridine-2-carbox...)
Affinity DataIC50: 1nMAssay Description:Inhibition of selectin E in human endothelial cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetE-selectin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50105227(4-[4-(Tetrahydro-pyran-2-yloxymethyl)-phenoxy]-thi...)
Affinity DataIC50: 2nMAssay Description:Inhibition of selectin E in human endothelial cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetE-selectin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50105201(4-(4-Imidazol-1-yl-phenoxy)-thieno[2,3-c]pyridine-...)
Affinity DataIC50: 2nMAssay Description:Inhibition of selectin E in human endothelial cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetE-selectin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50105155(4-(4-Cyano-phenoxy)-thieno[2,3-c]pyridine-2-carbox...)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of selectin E in human endothelial cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetE-selectin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50105215(4-(4-Cyano-phenoxy)-thieno[2,3-c]pyridine-2-carbox...)
Affinity DataIC50: 3nMAssay Description:Inhibition of selectin E in human endothelial cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetE-selectin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50105162(4-(4-Bromo-phenoxy)-thieno[2,3-c]pyridine-2-carbox...)
Affinity DataIC50: 4nMAssay Description:Inhibition of selectin E in human endothelial cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetE-selectin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50105162(4-(4-Bromo-phenoxy)-thieno[2,3-c]pyridine-2-carbox...)
Affinity DataIC50: 4nMAssay Description:In vitro inhibitory potency compared to TNF-alpha induced Selectin E expression in human endothelial cells (ELISA assay)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetE-selectin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50105195(4-(4-Pyrazol-1-yl-phenoxy)-thieno[2,3-c]pyridine-2...)
Affinity DataIC50: 4nMAssay Description:Inhibition of selectin E in human endothelial cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetE-selectin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50105156(4-{4-[2-(2-Methoxy-ethoxy)-ethoxymethyl]-phenoxy}-...)
Affinity DataIC50: 4nMAssay Description:In vitro inhibitory potency compared to TNF-alpha induced Selectin E in human endothelial cells (ELISA assay)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetE-selectin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50098480(4-(4-Bromo-phenylsulfanyl)-thieno[2,3-c]pyridine-2...)
Affinity DataIC50: 5nMAssay Description:In vitro potency against TNF alpha induced expression of Selectin E on human vascular endothelial cells using CAM ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetE-selectin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50105156(4-{4-[2-(2-Methoxy-ethoxy)-ethoxymethyl]-phenoxy}-...)
Affinity DataIC50: 5nMAssay Description:In vitro inhibitory potency compared to IL1-beta induced Selectin E in human endothelial cells (ELISA assay)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetE-selectin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50105183(4-(4-Furan-2-yl-phenoxy)-thieno[2,3-c]pyridine-2-c...)
Affinity DataIC50: 5nMAssay Description:Inhibition of selectin E in human endothelial cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetE-selectin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50105164(4-(4-Thiophen-2-yl-phenoxy)-thieno[2,3-c]pyridine-...)
Affinity DataIC50: 5nMAssay Description:Inhibition of selectin E in human endothelial cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetE-selectin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50105196(4-{4-[2-(2-Methoxy-ethoxy)-ethoxymethyl]-phenoxy}-...)
Affinity DataIC50: 5nMAssay Description:Inhibition of selectin E in human endothelial cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetE-selectin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50105172(4-[4-(2-Methoxy-ethoxymethyl)-phenoxy]-thieno[2,3-...)
Affinity DataIC50: 5nMAssay Description:Inhibition of selectin E in human endothelial cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetE-selectin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50105178(4-(4-Iodo-phenoxy)-thieno[2,3-c]pyridine-2-carboxy...)
Affinity DataIC50: 6nMAssay Description:Inhibition of selectin E in human endothelial cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetE-selectin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50105181(4-(4-Chloro-phenoxy)-thieno[2,3-c]pyridine-2-carbo...)
Affinity DataIC50: 6nMAssay Description:Inhibition of selectin E in human endothelial cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetE-selectin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50105162(4-(4-Bromo-phenoxy)-thieno[2,3-c]pyridine-2-carbox...)
Affinity DataIC50: 6nMAssay Description:In vitro inhibitory potency compared to IL1-beta induced Selectin E in human endothelial cells (ELISA assay)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetE-selectin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50105205(4-(4-Imidazol-1-yl-phenoxy)-thieno[2,3-c]pyridine-...)
Affinity DataIC50: 6nMAssay Description:Inhibition of selectin E in human endothelial cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetE-selectin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50105156(4-{4-[2-(2-Methoxy-ethoxy)-ethoxymethyl]-phenoxy}-...)
Affinity DataIC50: 6nMAssay Description:Inhibition of selectin E in human endothelial cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetE-selectin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50105180(4-(4-Bromo-phenoxy)-thieno[2,3-c]pyridine-2-carbox...)
Affinity DataIC50: 7nMAssay Description:Inhibition of selectin E in human endothelial cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetE-selectin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50105207(4-[4-(2-Methoxy-ethoxymethyl)-phenoxy]-thieno[2,3-...)
Affinity DataIC50: 7nMAssay Description:Inhibition of selectin E in human endothelial cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetE-selectin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50105204(4-(4-Chloro-3-fluoro-phenoxy)-thieno[2,3-c]pyridin...)
Affinity DataIC50: 8nMAssay Description:Inhibition of selectin E in human endothelial cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetE-selectin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50105159(4-(4-Chloro-phenoxy)-thieno[2,3-c]pyridine-2-carbo...)
Affinity DataIC50: 8nMAssay Description:Inhibition of selectin E in human endothelial cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetE-selectin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50105202(4-(Biphenyl-4-yloxy)-thieno[2,3-c]pyridine-2-carbo...)
Affinity DataIC50: 9nMAssay Description:Inhibition of selectin E in human endothelial cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetE-selectin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50098506(4-(4-Chloro-phenylsulfanyl)-thieno[2,3-c]pyridine-...)
Affinity DataIC50: 12nMAssay Description:In vitro potency against TNF alpha induced expression of Selectin E on human vascular endothelial cells using CAM ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetE-selectin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50098506(4-(4-Chloro-phenylsulfanyl)-thieno[2,3-c]pyridine-...)
Affinity DataIC50: 12nMAssay Description:Inhibition of selectin E in human endothelial cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetE-selectin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50098517(4-(3,4-Dimethyl-phenylsulfanyl)-thieno[2,3-c]pyrid...)
Affinity DataIC50: 13nMAssay Description:In vitro potency against TNF alpha induced expression of Selectin E on human vascular endothelial cells using CAM ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetE-selectin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50105160(4-[4-(N-Hydroxycarbamimidoyl)-phenoxy]-thieno[2,3-...)
Affinity DataIC50: 13nMAssay Description:Inhibition of selectin E in human endothelial cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetE-selectin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50105182(4-(4-Methoxymethyl-phenoxy)-thieno[2,3-c]pyridine-...)
Affinity DataIC50: 13nMAssay Description:Inhibition of selectin E in human endothelial cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetE-selectin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50105185(4-(4-Methoxymethyl-phenoxy)-thieno[2,3-c]pyridine-...)
Affinity DataIC50: 16nMAssay Description:Inhibition of selectin E in human endothelial cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetE-selectin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50105197(4-(4-Cyano-phenoxy)-thieno[2,3-c]pyridine-2-carbox...)
Affinity DataIC50: 18nMAssay Description:Inhibition of selectin E in human endothelial cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetE-selectin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50105222(4-(4-Trifluoromethyl-phenoxy)-thieno[2,3-c]pyridin...)
Affinity DataIC50: 19nMAssay Description:Inhibition of selectin E in human endothelial cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetE-selectin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50098512(4-p-Tolylsulfanyl-thieno[2,3-c]pyridine-2-carboxyl...)
Affinity DataIC50: 20nMAssay Description:In vitro potency against TNF alpha induced expression of Selectin E on human vascular endothelial cells using CAM ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetE-selectin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50098524(4-Phenylsulfanyl-thieno[2,3-c]pyridine-2-carboxyli...)
Affinity DataIC50: 20nMAssay Description:In vitro potency against TNF alpha induced expression of Selectin E on human vascular endothelial cells using CAM ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetE-selectin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50105170(4-p-Tolyloxy-thieno[2,3-c]pyridine-2-carboxylic ac...)
Affinity DataIC50: 20nMAssay Description:Inhibition of selectin E in human endothelial cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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