Compile Data Set for Download or QSAR
Report error Found 256 Enz. Inhib. hit(s) with Target = 'Dynamin-1'
TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524304(Preparation of 4'-(4-methyl-1-((2-(piperidin-1-yl)...)
Affinity DataIC50: 720nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. Robust colorimetric assays...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524237(Preparation of N-(4-(1H-tetrazol-5-yl)phenyl)-4-me...)
Affinity DataIC50: 910nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. Robust colorimetric assays...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetDynamin-1(Human)
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50625354(CHEMBL5397838)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of phosphotidylserine liposome-stimulated Dynamin 1 (unknown origin) GTPase activity by malachite green assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDynamin-1(Human)
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50625361(CHEMBL5400843)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of phosphotidylserine liposome-stimulated Dynamin 1 (unknown origin) GTPase activity by malachite green assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524266(Preparation of 4-methyl-1-((2-(piperidin-1-yl)thia...)
Affinity DataIC50: 1.20E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. Robust colorimetric assays...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524268(Preparation of N-(4-(1H-pyrazol-4-yl)phenyl)-4-met...)
Affinity DataIC50: 1.20E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. Robust colorimetric assays...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524269(Preparation of N-(4-(furan-3-yl)phenyl)-4-methyl-1...)
Affinity DataIC50: 1.20E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. Robust colorimetric assays...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524267(Preparation of N-(4-(3,5-dimethylisoxazol-4-yl)phe...)
Affinity DataIC50: 1.40E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. Robust colorimetric assays...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetDynamin-1(Human)
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50625349(CHEMBL1198288)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of phosphotidylserine liposome-stimulated Dynamin 1 (unknown origin) GTPase activity by malachite green assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524253(Preparation of 4-methyl-N-(naphthalen-2-yl)-1-((2-...)
Affinity DataIC50: 1.60E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. Robust colorimetric assays...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetDynamin-1(Human)
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50177923(2-cyano-N-{3-[2-cyano-3-(3,4,5-trihydroxyphenyl)ac...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibitory activity against dynamin1 GTPase expressed in sheep brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDynamin-1(Human)
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50177937(2-cyano-N-{3-[2-cyano-3-(3,4,5-trihydroxyphenyl)ac...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibitory activity against dynamin1 GTPase expressed in sheep brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDynamin-1(Human)
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50177941(2-cyano-N-{3-[2-cyano-3-(3,4,5-trihydroxyphenyl)ac...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibitory activity against dynamin1 GTPase expressed in sheep brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDynamin-1(Human)
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM5149(CHEMBL67535 | (2E)-2-cyano-N-{3-[(2E)-2-cyano-3-(3...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibitory activity against dynamin1 GTPase expressed in sheep brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524246(US11168080, Compound A-16)
Affinity DataIC50: 1.70E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. Robust colorimetric assays...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524256(Preparation of N-cyclohexyl-4-methyl-1-((2-(piperi...)
Affinity DataIC50: 1.70E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. Robust colorimetric assays...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524252(Preparation of 4-methyl-N-(4-(methylcarbamoyl)phen...)
Affinity DataIC50: 1.80E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. Robust colorimetric assays...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524284(Preparation of Methyl 4-phenyl-1-((2-(piperidin-1-...)
Affinity DataIC50: 1.80E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. Robust colorimetric assays...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524234(Preparation of Methyl 3-(4-methyl-1-((2-(piperidin...)
Affinity DataIC50: 1.90E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. Robust colorimetric assays...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetDynamin-1(Human)
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM5152((2E)-2-cyano-N-{4-[(2E)-2-cyano-3-(3,4,5-trihydrox...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibitory activity against dynamin1 GTPase expressed in sheep brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524285(US11168080, Compound A-52)
Affinity DataIC50: 2.10E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. Robust colorimetric assays...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524300(Preparation of N-(4-(1H-tetrazol-5-yl)phenyl)-4-me...)
Affinity DataIC50: 2.10E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. Robust colorimetric assays...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524234(Preparation of Methyl 3-(4-methyl-1-((2-(piperidin...)
Affinity DataIC50: 2.20E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. Robust colorimetric assays...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524291(Preparation of N-(4-(1H-tetrazol-5-yl)phenyl)-4-ph...)
Affinity DataIC50: 2.20E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. Robust colorimetric assays...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524303(Preparation of (2-bromothiazol-4-yl)methanol | US1...)
Affinity DataIC50: 2.30E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. Robust colorimetric assays...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524238(Preparation of 4-methyl-1-((2-(piperidin-1-yl)thia...)
Affinity DataIC50: 2.50E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. Robust colorimetric assays...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524294(Preparation of N-(4-iodo-3-methylphenyl)-4-methyl-...)
Affinity DataIC50: 2.50E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. Robust colorimetric assays...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524249(Preparation of Ethyl (3-methylpiperidine-1-carbono...)
Affinity DataIC50: 2.70E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. Robust colorimetric assays...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524290(Preparation of N-(3-fluoro-4-iodophenyl)-4-methyl-...)
Affinity DataIC50: 2.80E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. Robust colorimetric assays...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524271(Preparation of N-(1H-indazol-5-yl)-4-methyl-1-((2-...)
Affinity DataIC50: 2.90E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. Robust colorimetric assays...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetDynamin-1(Human)
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50147563(Trimethyl-octadecyl-ammonium; bromide | CHEMBL1094...)
Affinity DataIC50: 3.15E+3nMAssay Description:Concentration required against dynamin-1 GTPase activity of sheep brain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDynamin-1(Human)
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM5151((2E)-2-cyano-N-{4-[(2E)-2-cyano-3-(3,4-dihydroxyph...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibitory activity against dynamin1 GTPase expressed in sheep brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524213(US11168080, Compound A-2 | Preparation of Methyl 3...)
Affinity DataIC50: 3.20E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. Robust colorimetric assays...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetDynamin-1(Human)
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50268295(2-Cyano-N-octyl-3-(1-(3-dimethylaminopropyl)-1H-in...)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of phosphotidylserine liposome-stimulated Dynamin 1 (unknown origin) GTPase activity by malachite green assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524248(Preparation of 2-(azepan-1-yl)-4-(chloromethyl)thi...)
Affinity DataIC50: 3.40E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. Robust colorimetric assays...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524296(Preparation of 4-bromo-1-((2-(piperidin-1-yl)thiaz...)
Affinity DataIC50: 3.40E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. Robust colorimetric assays...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetDynamin-1(Human)
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50323462(3-hydroxy-N'-(3-hydroxy-4-methoxybenzylidene)-2-na...)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of GTPase activity of Dynamin 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524247(US11168080, Compound A-17)
Affinity DataIC50: 3.80E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. Robust colorimetric assays...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524250(Preparation of Ethyl 2-(2-methylpiperidin-1-yl)thi...)
Affinity DataIC50: 3.90E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. Robust colorimetric assays...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524272(Preparation of 4-methyl-N-(2-oxoindolin-5-yl)-1-((...)
Affinity DataIC50: 4.20E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. Robust colorimetric assays...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524275(Preparation of 4-methyl-N-(4-(2-oxoimidazolidin-1-...)
Affinity DataIC50: 4.30E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. Robust colorimetric assays...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetDynamin-1(Human)
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM58941(MLS001333620 | hexadecyl(trimethyl)ammonium;hydrox...)
Affinity DataIC50: 4.37E+3nMAssay Description:Concentration required against dynamin-1 GTPase activity of sheep brain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524263(Preparation of N-(4-iodophenyl)-4-methyl-1-((2-(pi...)
Affinity DataIC50: 4.50E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. Robust colorimetric assays...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524213(US11168080, Compound A-2 | Preparation of Methyl 3...)
Affinity DataIC50: 4.80E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. Robust colorimetric assays...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetDynamin-1(Human)
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM5153(CHEMBL144842 | (2E)-2-cyano-N-{5-[(2E)-2-cyano-3-(...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory activity against dynamin1 GTPase expressed in sheep brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDynamin-1(Human)
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50177943(2-cyano-N-{3-[2-cyano-3-(3,4-dihydroxy-5-methoxyph...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory activity against dynamin1 GTPase expressed in sheep brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDynamin-1(Human)
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50268295(2-Cyano-N-octyl-3-(1-(3-dimethylaminopropyl)-1H-in...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of dynamin 1-mediated endocytosis internalization of Tf-A594 in human U2OS cells pretreated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524236(Preparation of N-(4-(N-acetylsulfamoyl)phenyl)-4-m...)
Affinity DataIC50: 5.00E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. Robust colorimetric assays...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetDynamin-1(Human)
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50177940(2-cyano-N-{3-[2-cyano-3-(3,4-dihydroxyphenyl)acryl...)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibitory activity against dynamin1 GTPase expressed in sheep brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDynamin-1(Human)
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM5150(CHEMBL144908 | (2E)-2-cyano-N-{2-[(2E)-2-cyano-3-(...)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibitory activity against dynamin1 GTPase expressed in sheep brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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