Compile Data Set for Download or QSAR
Report error Found 49 Enz. Inhib. hit(s) with Target = 'Dual specificity protein phosphatase CDC14A'
TargetDual specificity protein phosphatase CDC14A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50638257(CHEMBL5567968)
Affinity DataIC50: 90nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDual specificity protein phosphatase CDC14A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50638257(CHEMBL5567968)
Affinity DataIC50: 93nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDual specificity protein phosphatase CDC14A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50638259(CHEMBL5568076)
Affinity DataIC50: 1.92E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDual specificity protein phosphatase CDC14A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50638263(CHEMBL5560702)
Affinity DataIC50: 2.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDual specificity protein phosphatase CDC14A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50638260(CHEMBL5568214)
Affinity DataIC50: 2.17E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDual specificity protein phosphatase CDC14A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50638264(CHEMBL5565218)
Affinity DataIC50: 2.74E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDual specificity protein phosphatase CDC14A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50638261(CHEMBL5563039)
Affinity DataIC50: 2.78E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDual specificity protein phosphatase CDC14A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50638262(CHEMBL5556755)
Affinity DataIC50: 3.21E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDual specificity protein phosphatase CDC14A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50425807(CHEMBL2316902)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of CDC14A (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetDual specificity protein phosphatase CDC14A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50425806(CHEMBL2316907)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of CDC14A (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetDual specificity protein phosphatase CDC14A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50087856(CHEMBL3426913)
Affinity DataIC50: 7.20E+3nMpH: 7.0Assay Description:Inhibition of CDC14A (unknown origin) using pNPP as substrate at pH 7 at 25 degC by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetDual specificity protein phosphatase CDC14A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50638258(CHEMBL5542122)
Affinity DataIC50: 9.41E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDual specificity protein phosphatase CDC14A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50638256(CHEMBL5561438)
Affinity DataIC50: 9.85E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDual specificity protein phosphatase CDC14A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50607111(CHEMBL5218807)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDC14A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetDual specificity protein phosphatase CDC14A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50054344(US9522881, 11a-1 L97M74 | CHEMBL3319356 | US984453...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of CDC14A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details Article
PubMed
TargetDual specificity protein phosphatase CDC14A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50054344(US9522881, 11a-1 L97M74 | CHEMBL3319356 | US984453...)
Affinity DataIC50: 1.60E+4nMAssay Description:For selectivity studies, the PTPs, including LYP, mPTPA, SHP1-D1C, PTP1B, LMPTP, VHR, Laforin and PTPα-D1D2 were expressed and purified from E. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2017
Entry Details
Go to US Patent

TargetDual specificity protein phosphatase CDC14A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50425808(CHEMBL2316906)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of CDC14A (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetDual specificity protein phosphatase CDC14A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50544431(CHEMBL4637459 | US11192850, Entry 4k)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CDC14A (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDual specificity protein phosphatase CDC14A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50544440(CHEMBL4647367 | US11192850, Entry 4t)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CDC14A (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDual specificity protein phosphatase CDC14A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50544427(CHEMBL4632818 | US11192850, Entry 4g)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CDC14A (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDual specificity protein phosphatase CDC14A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50343148(N1-(1-(4-(4-fluorophenyl)piperazin-1-yl)-1-(thioph...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human Cdc14A expressed in Escherichia coli after 5 mins by microplate spectrophotometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetDual specificity protein phosphatase CDC14A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50343147(N1-(furan-2-ylmethyl)-N2-(1-(4-(4-methoxyphenyl)pi...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human Cdc14A expressed in Escherichia coli after 5 mins by microplate spectrophotometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetDual specificity protein phosphatase CDC14A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50343142(N-(4-butylphenyl)-2-oxo-1,2-dihydrobenzo[cd]indole...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human Cdc14A expressed in Escherichia coli after 5 mins by microplate spectrophotometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetDual specificity protein phosphatase CDC14A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50308158(3-{1-[3-(biphenyl-4-ylamino)-3-oxopropyl]-1H-1,2,3...)
Affinity DataIC50: 5.00E+4nMpH: 7.0Assay Description:Inhibition of Cdc14A expressed in Escherichia coli assessed as inhibition of p-nitrophenyl phosphate hydrolysis at pH 7 by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetDual specificity protein phosphatase CDC14A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50112356(CHEMBL3609373)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of phosphatase activity of human CDC14A using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2016
Entry Details Article
PubMed
TargetDual specificity protein phosphatase CDC14A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50112358(CHEMBL3609374)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of phosphatase activity of human CDC14A using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2016
Entry Details Article
PubMed
TargetDual specificity protein phosphatase CDC14A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50112357(CHEMBL3609375)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of phosphatase activity of human CDC14A using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2016
Entry Details Article
PubMed
TargetDual specificity protein phosphatase CDC14A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50638251(CHEMBL5568311)
Affinity DataIC50: 9.87E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDual specificity protein phosphatase CDC14A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50558461(CHEMBL4760367)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of His-tagged CDC14A (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetDual specificity protein phosphatase CDC14A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50558485(CHEMBL4800195)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of His-tagged CDC14A (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetDual specificity protein phosphatase CDC14A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50607110(CHEMBL5219519)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CDC14A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetDual specificity protein phosphatase CDC14A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50638252(CHEMBL5555119)
Affinity DataIC50: 1.20E+5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDual specificity protein phosphatase CDC14A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50558486(CHEMBL4797766)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of His-tagged CDC14A (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetDual specificity protein phosphatase CDC14A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of CDC14A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetDual specificity protein phosphatase CDC14A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of His-tagged CDC14A (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetDual specificity protein phosphatase CDC14A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50558487(CHEMBL4786243)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of His-tagged CDC14A (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetDual specificity protein phosphatase CDC14A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50558484(CHEMBL4748824)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of His-tagged CDC14A (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetDual specificity protein phosphatase CDC14A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50558483(CHEMBL4778085)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of His-tagged CDC14A (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetDual specificity protein phosphatase CDC14A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50558482(CHEMBL4742123)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of His-tagged CDC14A (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetDual specificity protein phosphatase CDC14A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50558481(CHEMBL4783639)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of His-tagged CDC14A (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetDual specificity protein phosphatase CDC14A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50638250(CHEMBL5563600)
Affinity DataIC50: 2.21E+5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDual specificity protein phosphatase CDC14A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50638253(CHEMBL5559251)
Affinity DataIC50: 2.73E+5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDual specificity protein phosphatase CDC14A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50420258(CEFSULODIN)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of phosphatase activity of human CDC14A using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2016
Entry Details Article
PubMed
TargetDual specificity protein phosphatase CDC14A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50638254(CHEMBL5560087)
Affinity DataIC50: 3.39E+5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDual specificity protein phosphatase CDC14A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50638255(CHEMBL5556892)
Affinity DataIC50: 3.60E+5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDual specificity protein phosphatase CDC14A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50102186((Difluoro-phenyl-methyl)-phosphonic acid | Difluor...)
Affinity DataIC50: 3.27E+6nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDual specificity protein phosphatase CDC14A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50638257(CHEMBL5567968)
Affinity DataKi:  57nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDual specificity protein phosphatase CDC14A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM199180(US9217012, 10)
Affinity DataKi: >1.00E+3nM ΔG°: >-34.2kJ/molepH: 7.0 T: 2°CAssay Description:PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in DMG buffer (50 mM DMG, pH 7.0, 1 mM EDTA, 150 mM NaCl, 2 mM DTT, 0.1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2016
Entry Details
Go to US Patent

TargetDual specificity protein phosphatase CDC14A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50638256(CHEMBL5561438)
Affinity DataKi:  5.80E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed