Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with Target = 'Dual specificity mitogen-activated protein kinase kinase 1 [2-31,52-393,S218E,S222D]'
LigandPNGBDBM50337920(CHEMBL1684063 | US8470837, 6 | (R)-3-(2,3-dihydrox...)
Affinity DataIC50: 5nMpH: 7.3 T: 2°CAssay Description:The inhibitory properties of compounds relative to MEK1 or MEK2 may be determined using a black 384-well-plate format under the following reaction co...More data for this Ligand-Target Pair
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Date in BDB:
7/24/2013
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LigandPNGBDBM50337928(US8470837, 22 | CHEMBL1684069 | (R)-3-(2,3-dihydro...)
Affinity DataIC50: 5nMpH: 7.3 T: 2°CAssay Description:The inhibitory properties of compounds relative to MEK1 or MEK2 may be determined using a black 384-well-plate format under the following reaction co...More data for this Ligand-Target Pair
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Date in BDB:
7/24/2013
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LigandPNGBDBM50337933(US8470837, 25 | CHEMBL1684074 | 3-(1,3-dihydroxypr...)
Affinity DataIC50: 5nMpH: 7.3 T: 2°CAssay Description:The inhibitory properties of compounds relative to MEK1 or MEK2 may be determined using a black 384-well-plate format under the following reaction co...More data for this Ligand-Target Pair
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Date in BDB:
7/24/2013
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LigandPNGBDBM50337929(US8470837, 19 | CHEMBL1684070 | (S)-3-(2,3-dihydro...)
Affinity DataIC50: 5nMpH: 7.3 T: 2°CAssay Description:The inhibitory properties of compounds relative to MEK1 or MEK2 may be determined using a black 384-well-plate format under the following reaction co...More data for this Ligand-Target Pair
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Date in BDB:
7/24/2013
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LigandPNGBDBM50337926(3-[(2R)-2,3-dihydroxypropyl]-6-fluoro-5-[(2-fluoro...)
Affinity DataIC50: 5nMpH: 7.3 T: 2°CAssay Description:The inhibitory properties of compounds relative to MEK1 or MEK2 may be determined using a black 384-well-plate format under the following reaction co...More data for this Ligand-Target Pair
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Date in BDB:
7/24/2013
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LigandPNGBDBM50337932(CHEMBL1684073 | US8470837, 14 | 5-(2-fluoro-4-iodo...)
Affinity DataIC50: 5nMpH: 7.3 T: 2°CAssay Description:The inhibitory properties of compounds relative to MEK1 or MEK2 may be determined using a black 384-well-plate format under the following reaction co...More data for this Ligand-Target Pair
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Date in BDB:
7/24/2013
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LigandPNGBDBM97644(US8470837, 12)
Affinity DataIC50: 5nMpH: 7.3 T: 2°CAssay Description:The inhibitory properties of compounds relative to MEK1 or MEK2 may be determined using a black 384-well-plate format under the following reaction co...More data for this Ligand-Target Pair
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Date in BDB:
7/24/2013
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LigandPNGBDBM50337934(US8470837, 28 | CHEMBL1684075 | (R)-3-(2,3-dihydro...)
Affinity DataIC50: 5nMpH: 7.3 T: 2°CAssay Description:The inhibitory properties of compounds relative to MEK1 or MEK2 may be determined using a black 384-well-plate format under the following reaction co...More data for this Ligand-Target Pair
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Date in BDB:
7/24/2013
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LigandPNGBDBM97641(US8470837, 7)
Affinity DataIC50: 5nMpH: 7.3 T: 2°CAssay Description:The inhibitory properties of compounds relative to MEK1 or MEK2 may be determined using a black 384-well-plate format under the following reaction co...More data for this Ligand-Target Pair
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Date in BDB:
7/24/2013
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LigandPNGBDBM97651(US8470837, 30)
Affinity DataIC50: 5nMpH: 7.3 T: 2°CAssay Description:The inhibitory properties of compounds relative to MEK1 or MEK2 may be determined using a black 384-well-plate format under the following reaction co...More data for this Ligand-Target Pair
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Date in BDB:
7/24/2013
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LigandPNGBDBM50337937(US8470837, 31 | CHEMBL1684062 | 5-(2-fluoro-4-iodo...)
Affinity DataIC50: 5nMpH: 7.3 T: 2°CAssay Description:The inhibitory properties of compounds relative to MEK1 or MEK2 may be determined using a black 384-well-plate format under the following reaction co...More data for this Ligand-Target Pair
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Date in BDB:
7/24/2013
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LigandPNGBDBM97652(US8470837, 32)
Affinity DataIC50: 5nMpH: 7.3 T: 2°CAssay Description:The inhibitory properties of compounds relative to MEK1 or MEK2 may be determined using a black 384-well-plate format under the following reaction co...More data for this Ligand-Target Pair
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Date in BDB:
7/24/2013
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LigandPNGBDBM1714(CHEMBL1684071 | US8470837, 13)
Affinity DataIC50: 5nMpH: 7.3 T: 2°CAssay Description:The inhibitory properties of compounds relative to MEK1 or MEK2 may be determined using a black 384-well-plate format under the following reaction co...More data for this Ligand-Target Pair
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Date in BDB:
7/24/2013
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LigandPNGBDBM1711(CHEMBL1684067 | US8470837, 8)
Affinity DataIC50: 5nMpH: 7.3 T: 2°CAssay Description:The inhibitory properties of compounds relative to MEK1 or MEK2 may be determined using a black 384-well-plate format under the following reaction co...More data for this Ligand-Target Pair
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Date in BDB:
7/24/2013
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LigandPNGBDBM97662(US8470837, 4)
Affinity DataIC50: 10nMpH: 7.3 T: 2°CAssay Description:The inhibitory properties of compounds relative to MEK1 or MEK2 may be determined using a black 384-well-plate format under the following reaction co...More data for this Ligand-Target Pair
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Date in BDB:
7/24/2013
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LigandPNGBDBM97650(US8470837, 29)
Affinity DataIC50: 10nMpH: 7.3 T: 2°CAssay Description:The inhibitory properties of compounds relative to MEK1 or MEK2 may be determined using a black 384-well-plate format under the following reaction co...More data for this Ligand-Target Pair
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Date in BDB:
7/24/2013
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LigandPNGBDBM97654(US8470837, 34)
Affinity DataIC50: 10nMpH: 7.3 T: 2°CAssay Description:The inhibitory properties of compounds relative to MEK1 or MEK2 may be determined using a black 384-well-plate format under the following reaction co...More data for this Ligand-Target Pair
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Date in BDB:
7/24/2013
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LigandPNGBDBM97658(US8470837, 40)
Affinity DataIC50: 10nMpH: 7.3 T: 2°CAssay Description:The inhibitory properties of compounds relative to MEK1 or MEK2 may be determined using a black 384-well-plate format under the following reaction co...More data for this Ligand-Target Pair
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Date in BDB:
7/24/2013
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LigandPNGBDBM97660(US8470837, 43)
Affinity DataIC50: 10nMpH: 7.3 T: 2°CAssay Description:The inhibitory properties of compounds relative to MEK1 or MEK2 may be determined using a black 384-well-plate format under the following reaction co...More data for this Ligand-Target Pair
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Date in BDB:
7/24/2013
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LigandPNGBDBM97649(US8470837, 27)
Affinity DataIC50: 10nMpH: 7.3 T: 2°CAssay Description:The inhibitory properties of compounds relative to MEK1 or MEK2 may be determined using a black 384-well-plate format under the following reaction co...More data for this Ligand-Target Pair
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Date in BDB:
7/24/2013
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LigandPNGBDBM97648(US8470837, 26)
Affinity DataIC50: 10nMpH: 7.3 T: 2°CAssay Description:The inhibitory properties of compounds relative to MEK1 or MEK2 may be determined using a black 384-well-plate format under the following reaction co...More data for this Ligand-Target Pair
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Date in BDB:
7/24/2013
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LigandPNGBDBM97661(US8470837, 44)
Affinity DataIC50: 10nMpH: 7.3 T: 2°CAssay Description:The inhibitory properties of compounds relative to MEK1 or MEK2 may be determined using a black 384-well-plate format under the following reaction co...More data for this Ligand-Target Pair
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Date in BDB:
7/24/2013
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LigandPNGBDBM1665(CHEMBL1684061 | US8470837, 2)
Affinity DataIC50: 10nMpH: 7.3 T: 2°CAssay Description:The inhibitory properties of compounds relative to MEK1 or MEK2 may be determined using a black 384-well-plate format under the following reaction co...More data for this Ligand-Target Pair
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Date in BDB:
7/24/2013
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LigandPNGBDBM1710(CHEMBL1684064 | US8470837, 5)
Affinity DataIC50: 10nMpH: 7.3 T: 2°CAssay Description:The inhibitory properties of compounds relative to MEK1 or MEK2 may be determined using a black 384-well-plate format under the following reaction co...More data for this Ligand-Target Pair
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Date in BDB:
7/24/2013
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LigandPNGBDBM97646(US8470837, 16)
Affinity DataIC50: 10nMpH: 7.3 T: 2°CAssay Description:The inhibitory properties of compounds relative to MEK1 or MEK2 may be determined using a black 384-well-plate format under the following reaction co...More data for this Ligand-Target Pair
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Date in BDB:
7/24/2013
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LigandPNGBDBM1716(CHEMBL1684072 | US8470837, 17)
Affinity DataIC50: 10nMpH: 7.3 T: 2°CAssay Description:The inhibitory properties of compounds relative to MEK1 or MEK2 may be determined using a black 384-well-plate format under the following reaction co...More data for this Ligand-Target Pair
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Date in BDB:
7/24/2013
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LigandPNGBDBM1717(US8470837, 21)
Affinity DataIC50: 10nMpH: 7.3 T: 2°CAssay Description:The inhibitory properties of compounds relative to MEK1 or MEK2 may be determined using a black 384-well-plate format under the following reaction co...More data for this Ligand-Target Pair
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Date in BDB:
7/24/2013
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LigandPNGBDBM1722(US8470837, 41)
Affinity DataIC50: 10nMpH: 7.3 T: 2°CAssay Description:The inhibitory properties of compounds relative to MEK1 or MEK2 may be determined using a black 384-well-plate format under the following reaction co...More data for this Ligand-Target Pair
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Date in BDB:
7/24/2013
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LigandPNGBDBM97647(US8470837, 24)
Affinity DataIC50: 10nMpH: 7.3 T: 2°CAssay Description:The inhibitory properties of compounds relative to MEK1 or MEK2 may be determined using a black 384-well-plate format under the following reaction co...More data for this Ligand-Target Pair
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Date in BDB:
7/24/2013
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LigandPNGBDBM1719(US8470837, 23)
Affinity DataIC50: 16nMpH: 7.3 T: 2°CAssay Description:The inhibitory properties of compounds relative to MEK1 or MEK2 may be determined using a black 384-well-plate format under the following reaction co...More data for this Ligand-Target Pair
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Date in BDB:
7/24/2013
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LigandPNGBDBM1713(US8470837, 9)
Affinity DataIC50: 16nMpH: 7.3 T: 2°CAssay Description:The inhibitory properties of compounds relative to MEK1 or MEK2 may be determined using a black 384-well-plate format under the following reaction co...More data for this Ligand-Target Pair
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Date in BDB:
7/24/2013
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LigandPNGBDBM97659(US8470837, 42)
Affinity DataIC50: 16nMpH: 7.3 T: 2°CAssay Description:The inhibitory properties of compounds relative to MEK1 or MEK2 may be determined using a black 384-well-plate format under the following reaction co...More data for this Ligand-Target Pair
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Date in BDB:
7/24/2013
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LigandPNGBDBM50337922(US8470837, 39 | CHEMBL1684065 | (S)-3-(2,4-dihydro...)
Affinity DataIC50: 16nMpH: 7.3 T: 2°CAssay Description:The inhibitory properties of compounds relative to MEK1 or MEK2 may be determined using a black 384-well-plate format under the following reaction co...More data for this Ligand-Target Pair
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Date in BDB:
7/24/2013
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LigandPNGBDBM97657(US8470837, 38)
Affinity DataIC50: 16nMpH: 7.3 T: 2°CAssay Description:The inhibitory properties of compounds relative to MEK1 or MEK2 may be determined using a black 384-well-plate format under the following reaction co...More data for this Ligand-Target Pair
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Date in BDB:
7/24/2013
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LigandPNGBDBM50337923(US8470837, 37 | CHEMBL1684066 | 3-(2-(dimethylamin...)
Affinity DataIC50: 16nMpH: 7.3 T: 2°CAssay Description:The inhibitory properties of compounds relative to MEK1 or MEK2 may be determined using a black 384-well-plate format under the following reaction co...More data for this Ligand-Target Pair
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Date in BDB:
7/24/2013
Entry Details
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LigandPNGBDBM97656(US8470837, 36)
Affinity DataIC50: 16nMpH: 7.3 T: 2°CAssay Description:The inhibitory properties of compounds relative to MEK1 or MEK2 may be determined using a black 384-well-plate format under the following reaction co...More data for this Ligand-Target Pair
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Date in BDB:
7/24/2013
Entry Details
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LigandPNGBDBM97655(US8470837, 35)
Affinity DataIC50: 16nMpH: 7.3 T: 2°CAssay Description:The inhibitory properties of compounds relative to MEK1 or MEK2 may be determined using a black 384-well-plate format under the following reaction co...More data for this Ligand-Target Pair
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Date in BDB:
7/24/2013
Entry Details
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LigandPNGBDBM97653(US8470837, 33)
Affinity DataIC50: 16nMpH: 7.3 T: 2°CAssay Description:The inhibitory properties of compounds relative to MEK1 or MEK2 may be determined using a black 384-well-plate format under the following reaction co...More data for this Ligand-Target Pair
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Date in BDB:
7/24/2013
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LigandPNGBDBM50337935(US8470837, 1 | CHEMBL1684060 | 5-(2-fluoro-4-iodop...)
Affinity DataIC50: 16nMpH: 7.3 T: 2°CAssay Description:The inhibitory properties of compounds relative to MEK1 or MEK2 may be determined using a black 384-well-plate format under the following reaction co...More data for this Ligand-Target Pair
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Date in BDB:
7/24/2013
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LigandPNGBDBM97640(US8470837, 3)
Affinity DataIC50: 16nMpH: 7.3 T: 2°CAssay Description:The inhibitory properties of compounds relative to MEK1 or MEK2 may be determined using a black 384-well-plate format under the following reaction co...More data for this Ligand-Target Pair
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Date in BDB:
7/24/2013
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LigandPNGBDBM97642(US8470837, 10)
Affinity DataIC50: 16nMpH: 7.3 T: 2°CAssay Description:The inhibitory properties of compounds relative to MEK1 or MEK2 may be determined using a black 384-well-plate format under the following reaction co...More data for this Ligand-Target Pair
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Date in BDB:
7/24/2013
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LigandPNGBDBM97643(US8470837, 11)
Affinity DataIC50: 16nMpH: 7.3 T: 2°CAssay Description:The inhibitory properties of compounds relative to MEK1 or MEK2 may be determined using a black 384-well-plate format under the following reaction co...More data for this Ligand-Target Pair
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Date in BDB:
7/24/2013
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LigandPNGBDBM97645(US8470837, 15)
Affinity DataIC50: 16nMpH: 7.3 T: 2°CAssay Description:The inhibitory properties of compounds relative to MEK1 or MEK2 may be determined using a black 384-well-plate format under the following reaction co...More data for this Ligand-Target Pair
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Date in BDB:
7/24/2013
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LigandPNGBDBM50337927(CHEMBL1684068 | US8470837, 20 | (R)-5-(4-bromo-2-f...)
Affinity DataIC50: 16nMpH: 7.3 T: 2°CAssay Description:The inhibitory properties of compounds relative to MEK1 or MEK2 may be determined using a black 384-well-plate format under the following reaction co...More data for this Ligand-Target Pair
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Date in BDB:
7/24/2013
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