Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with Target = 'DNA-directed RNA polymerase II subunit RPB1'
TargetDNA-directed RNA polymerase II subunit RPB1(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50365463(CHEMBL1232461)
Affinity DataKd:  157nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDNA-directed RNA polymerase II subunit RPB1(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50365463(CHEMBL1232461)
Affinity DataIC50: 150nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDNA-directed RNA polymerase II subunit RPB1(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50193060(3-cyclohexyl-2-(furan-3-yl)-1H-indole-6-carboxylic...)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of calf thymus DNA dependent RNA polymerase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetDNA-directed RNA polymerase II subunit RPB1(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50193054(3-cyclohexyl-2-(furan-3-yl)-1-methyl-1H-indole-6-c...)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of calf thymus DNA dependent RNA polymerase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetDNA-directed RNA polymerase II subunit RPB1(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50333128(((2S,4R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-4-...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of human RNA polymerase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetDNA-directed RNA polymerase II subunit RPB1(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50333129(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of human RNA polymerase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed