Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with Target = 'DNA primase'
TargetDNA primase(HHV-1)
Stanford University Medical School

Curated by ChEMBL
LigandPNGBDBM50034949(2-Amino-6-(3,5-dichloro-phenylamino)-3H-pyrimidin-...)
Affinity DataIC50: 770nMAssay Description:Inhibition against DNA-Dependent GTPase activity of HSV-1 helicase-primase in HSV-1-infected CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA primase(HHV-1)
Stanford University Medical School

Curated by ChEMBL
LigandPNGBDBM50034955(N*2*-(3,4-Dichloro-phenyl)-9H-purine-2,6-diamine |...)
Affinity DataIC50: 850nMAssay Description:Inhibition against DNA-Dependent GTPase activity of HSV-1 helicase-primase in HSV-1-infected CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA primase(HHV-1)
Stanford University Medical School

Curated by ChEMBL
LigandPNGBDBM50034950(2-Amino-6-(3,4-dichloro-phenylamino)-3H-pyrimidin-...)
Affinity DataIC50: 850nMAssay Description:Inhibition against DNA-Dependent GTPase activity of HSV-1 helicase-primase in HSV-1-infected CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA primase(HHV-1)
Stanford University Medical School

Curated by ChEMBL
LigandPNGBDBM50013091(CHEMBL51613 | 2-(3,4-Dichloro-phenylamino)-1,9-dih...)
Affinity DataIC50: 880nMAssay Description:Inhibition against DNA-Dependent GTPase activity of HSV-1 helicase-primase in HSV-1-infected CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA primase(HHV-1)
Stanford University Medical School

Curated by ChEMBL
LigandPNGBDBM50034947(2-(3,5-Dichloro-phenylamino)-1,9-dihydro-purin-6-o...)
Affinity DataIC50: 910nMAssay Description:Inhibition against DNA-Dependent GTPase activity of HSV-1 helicase-primase in HSV-1-infected CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA primase(HHV-1)
Stanford University Medical School

Curated by ChEMBL
LigandPNGBDBM50034963(N*2*-(3,5-Dichloro-phenyl)-9H-purine-2,6-diamine |...)
Affinity DataIC50: 920nMAssay Description:Inhibition against DNA-Dependent GTPase activity of HSV-1 helicase-primase in HSV-1-infected CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA primase(HHV-1)
Stanford University Medical School

Curated by ChEMBL
LigandPNGBDBM50028342(6-(3,4-Dichloro-phenylamino)-1H-pyrimidine-2,4-dio...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition against DNA-Dependent GTPase activity of HSV-1 helicase-primase in HSV-1-infected CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA primase(HHV-1)
Stanford University Medical School

Curated by ChEMBL
LigandPNGBDBM50034952(6-(3,5-Dichloro-phenylamino)-1H-pyrimidine-2,4-dio...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition against DNA-Dependent GTPase activity of HSV-1 helicase-primase in HSV-1-infected CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA primase(Bacillus anthracis)
University of Michigan

LigandPNGBDBM22984(Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...)
Affinity DataIC50: 4.40E+3nMpH: 8.8Assay Description:The reaction mixture contained DNA (1.25 uM or as specified), NTP (110 uM or as specified), 50 mM NaCl, 150 mM potassium glutamate, buffer [20 mM CAP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2014
Entry Details Article
PubMed
TargetDNA primase(Bacillus anthracis)
University of Michigan

LigandPNGBDBM50364890(Amixin IC | TILORONE | cid_5475)
Affinity DataIC50: 7.10E+3nMpH: 8.8Assay Description:The reaction mixture contained DNA (1.25 uM or as specified), NTP (110 uM or as specified), 50 mM NaCl, 150 mM potassium glutamate, buffer [20 mM CAP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2014
Entry Details Article
PubMed
TargetDNA primase(Bacillus anthracis)
University of Michigan

LigandPNGBDBM50336799(Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...)
Affinity DataIC50: 8.20E+3nMpH: 8.8Assay Description:The reaction mixture contained DNA (1.25 uM or as specified), NTP (110 uM or as specified), 50 mM NaCl, 150 mM potassium glutamate, buffer [20 mM CAP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2014
Entry Details Article
PubMed
TargetDNA primase(HHV-1)
Stanford University Medical School

Curated by ChEMBL
LigandPNGBDBM50034961(6-Chloro-N*4*-(3,4-dichloro-phenyl)-pyrimidine-2,4...)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition against Primase by coupled primase-DNA polymerase-I assay with the two subunit recombinant HSV-1 helicase primaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA primase(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
University of Michigan

LigandPNGBDBM22984(Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...)
Affinity DataIC50: 9.30E+3nMpH: 8.8Assay Description:The reaction mixture contained DNA (1.25 uM or as specified), NTP (110 uM or as specified), 50 mM NaCl, 150 mM potassium glutamate, buffer [20 mM CAP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2014
Entry Details Article
PubMed
TargetDNA primase(HHV-1)
Stanford University Medical School

Curated by ChEMBL
LigandPNGBDBM50034955(N*2*-(3,4-Dichloro-phenyl)-9H-purine-2,6-diamine |...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition against Primase by coupled primase-DNA polymerase-I assay with the two subunit recombinant HSV-1 helicase primaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA primase(HHV-1)
Stanford University Medical School

Curated by ChEMBL
LigandPNGBDBM50013091(CHEMBL51613 | 2-(3,4-Dichloro-phenylamino)-1,9-dih...)
Affinity DataIC50: 5.90E+4nMAssay Description:Inhibition against Primase by coupled primase-DNA polymerase-I assay with the two subunit recombinant HSV-1 helicase primaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA primase(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
University of Michigan

LigandPNGBDBM50364890(Amixin IC | TILORONE | cid_5475)
Affinity DataIC50: 6.90E+4nMpH: 8.8Assay Description:The reaction mixture contained DNA (1.25 uM or as specified), NTP (110 uM or as specified), 50 mM NaCl, 150 mM potassium glutamate, buffer [20 mM CAP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2014
Entry Details Article
PubMed
TargetDNA primase(Bacillus anthracis)
University of Michigan

LigandPNGBDBM50366826(Levaquin | Iquix | Floxacin | DR-3355 | LEVOFLOXAC...)
Affinity DataIC50: 7.50E+4nMpH: 8.8Assay Description:The reaction mixture contained DNA (1.25 uM or as specified), NTP (110 uM or as specified), 50 mM NaCl, 150 mM potassium glutamate, buffer [20 mM CAP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2014
Entry Details Article
PubMed
TargetDNA primase(HHV-1)
Stanford University Medical School

Curated by ChEMBL
LigandPNGBDBM50137912((Biphenyl-4-sulfinyl)-acetic acid | (Biphenyl-4-su...)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibitory concentration against herpes simplex virus helicase primase 8 (HSV)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA primase(Bacillus anthracis)
University of Michigan

LigandPNGBDBM4078(Elagic Acid | CHEMBL6246 | 6,7,13,14-tetrahydroxy-...)
Affinity DataIC50: 1.00E+5nMpH: 8.8Assay Description:The reaction mixture contained DNA (1.25 uM or as specified), NTP (110 uM or as specified), 50 mM NaCl, 150 mM potassium glutamate, buffer [20 mM CAP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2014
Entry Details Article
PubMed
TargetDNA primase TraC(Escherichia coli)
University of Nebraska-Lincoln

Curated by ChEMBL
LigandPNGBDBM15236(CHEMBL164 | Cannabiscetin | 3,5,7-trihydroxy-2-(3,...)
Affinity DataIC50: 7.00E+5nMAssay Description:Inhibition of Escherichia coli primaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed