Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with Target = 'Cytohesin-3'
TargetCytohesin-3(Rat)
Kumamoto Health Science University

Curated by ChEMBL
LigandPNGBDBM50357881(CHEMBL1916340)
Affinity DataKd:  140nMAssay Description:Binding affinity to recombinant rat brain Grp1 PH domain (amino acids 1 to 120) after 10 mins by pull-down assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCytohesin-3(Rat)
Kumamoto Health Science University

Curated by ChEMBL
LigandPNGBDBM50357881(CHEMBL1916340)
Affinity DataKd:  300nMAssay Description:Binding affinity to recombinant rat brain Grp1 PH domain (amino acids 1 to 120) by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCytohesin-3(Rat)
Kumamoto Health Science University

Curated by ChEMBL
LigandPNGBDBM50357882(CHEMBL1916341)
Affinity DataKd: >1.00E+3nMAssay Description:Binding affinity to recombinant rat brain Grp1 PH domain (amino acids 1 to 120) by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCytohesin-3(Rat)
Kumamoto Health Science University

Curated by ChEMBL
LigandPNGBDBM50357883(CHEMBL1916342)
Affinity DataKd: >1.00E+3nMAssay Description:Binding affinity to recombinant rat brain Grp1 PH domain (amino acids 1 to 120) by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCytohesin-3(Rat)
Kumamoto Health Science University

Curated by ChEMBL
LigandPNGBDBM50075651(1D-myo-inositol 1,3,4,5-tetrakis(dihydrogen phosph...)
Affinity DataKd:  100nMAssay Description:Binding affinity to recombinant rat brain Grp1 PH domain (amino acids 1 to 120) after 10 mins by pull-down assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCytohesin-3(Human)
Tufts University

US Patent
LigandPNGBDBM112785(US8628961, DM-PIT-1)
Affinity DataIC50: 3.55E+4nMpH: 7.5 T: 2°CAssay Description:In order to identify compounds that disrupt the interaction between PIP3 and PH domains, a high-throughput fluorescence polarization (FP)-binding ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2014
Entry Details
Go to US Patent

TargetCytohesin-3(Human)
Tufts University

US Patent
LigandPNGBDBM50013327(CHEMBL3263343)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of recombinant C-terminal 6xHis-tagged Grp1 PH domain (unknown origin) expressed in Escherichia coli BL21(DE3) RIL assessed as inhibition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetCytohesin-3(Human)
Tufts University

US Patent
LigandPNGBDBM112784(US8628961, PIT-1)
Affinity DataIC50: 4.03E+4nMpH: 7.5 T: 2°CAssay Description:In order to identify compounds that disrupt the interaction between PIP3 and PH domains, a high-throughput fluorescence polarization (FP)-binding ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2014
Entry Details
Go to US Patent