Report error Found 495 Enz. Inhib. hit(s) with Target = 'Cytochrome b'
Affinity DataEC50: 500nMAssay Description:Inhibition of NOX2 (unknown origin) transfected in HEK cellsMore data for this Ligand-Target Pair
Ligand Info
TargetCytochrome b-c1 complex subunit 1, mitochondrial(Homo sapiens)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Ligand Info
TargetCytochrome b-c1 complex subunit 1, mitochondrial(Homo sapiens)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Ligand Info
TargetCytochrome b-c1 complex subunit 2, mitochondrial(Homo sapiens)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Ligand Info
TargetCytochrome b-c1 complex subunit 2, mitochondrial(Homo sapiens)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Ligand Info
Affinity DataIC50: 5nMpH: 7.4 T: 2°CAssay Description:The cytochrome b enzyme assay was adapted from previous studies (Gutierrez-Cirlos et al., 2004). Briefly, compounds were diluted in a 23 reaction buf...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMpH: 7.4 T: 2°CAssay Description:The cytochrome b enzyme assay was adapted from previous studies (Gutierrez-Cirlos et al., 2004). Briefly, compounds were diluted in a 23 reaction buf...More data for this Ligand-Target Pair
Affinity DataIC50: 26nMpH: 7.4 T: 2°CAssay Description:The cytochrome b enzyme assay was adapted from previous studies (Gutierrez-Cirlos et al., 2004). Briefly, compounds were diluted in a 23 reaction buf...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of full length human NOX2 transfected in COS 22 cells assessed as inhibition of lithium dodecyl sulphate-stimulated ROS generation preincu...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of full length human NOX2 transfected in COS 22 cells assessed as inhibition of lithium dodecyl sulphate-stimulated ROS generation preincu...More data for this Ligand-Target Pair
Affinity DataIC50: 35.2nMpH: 7.4 T: 2°CAssay Description:The cytochrome b enzyme assay was adapted from previous studies (Gutierrez-Cirlos et al., 2004). Briefly, compounds were diluted in a 23 reaction buf...More data for this Ligand-Target Pair
Affinity DataIC50: 38.8nMpH: 7.4 T: 2°CAssay Description:The cytochrome b enzyme assay was adapted from previous studies (Gutierrez-Cirlos et al., 2004). Briefly, compounds were diluted in a 23 reaction buf...More data for this Ligand-Target Pair
Affinity DataIC50: 66.3nMpH: 7.4 T: 2°CAssay Description:The cytochrome b enzyme assay was adapted from previous studies (Gutierrez-Cirlos et al., 2004). Briefly, compounds were diluted in a 23 reaction buf...More data for this Ligand-Target Pair
Affinity DataIC50: 87nMpH: 7.4 T: 2°CAssay Description:The cytochrome b enzyme assay was adapted from previous studies (Gutierrez-Cirlos et al., 2004). Briefly, compounds were diluted in a 23 reaction buf...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of NOX2 in human PLB-985 cells assessed as inhibition of PMA-induced hydrogen peroxide production pretreated for 15 mins followed by PMA s...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of human NOX2 transfected in PLB-985 cells assessed as PMA-induced hydrogen peroxide pre-incubated for 10 and measured after 15 mins by Am...More data for this Ligand-Target Pair
Affinity DataIC50: 129nMpH: 7.4 T: 2°CAssay Description:The cytochrome b enzyme assay was adapted from previous studies (Gutierrez-Cirlos et al., 2004). Briefly, compounds were diluted in a 23 reaction buf...More data for this Ligand-Target Pair
Affinity DataIC50: 141nMpH: 7.4 T: 2°CAssay Description:The cytochrome b enzyme assay was adapted from previous studies (Gutierrez-Cirlos et al., 2004). Briefly, compounds were diluted in a 23 reaction buf...More data for this Ligand-Target Pair
Affinity DataIC50: 145nMpH: 7.4 T: 2°CAssay Description:The cytochrome b enzyme assay was adapted from previous studies (Gutierrez-Cirlos et al., 2004). Briefly, compounds were diluted in a 23 reaction buf...More data for this Ligand-Target Pair
Affinity DataIC50: 149nMAssay Description:Inhibition of NOX2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 154nMpH: 7.4 T: 2°CAssay Description:The cytochrome b enzyme assay was adapted from previous studies (Gutierrez-Cirlos et al., 2004). Briefly, compounds were diluted in a 23 reaction buf...More data for this Ligand-Target Pair
Affinity DataIC50: 156nMpH: 7.4 T: 2°CAssay Description:The cytochrome b enzyme assay was adapted from previous studies (Gutierrez-Cirlos et al., 2004). Briefly, compounds were diluted in a 23 reaction buf...More data for this Ligand-Target Pair
Affinity DataIC50: 289nMpH: 7.4 T: 2°CAssay Description:The cytochrome b enzyme assay was adapted from previous studies (Gutierrez-Cirlos et al., 2004). Briefly, compounds were diluted in a 23 reaction buf...More data for this Ligand-Target Pair
Affinity DataIC50: 300nMpH: 7.4 T: 2°CAssay Description:The cytochrome b enzyme assay was adapted from previous studies (Gutierrez-Cirlos et al., 2004). Briefly, compounds were diluted in a 23 reaction buf...More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of human NOX2 expressed in HEK cells assessed as inhibition of ionomycin-induced hydrogen peroxide production pre-incubated for 15 mins fo...More data for this Ligand-Target Pair
Affinity DataIC50: 344nMpH: 7.4 T: 2°CAssay Description:The cytochrome b enzyme assay was adapted from previous studies (Gutierrez-Cirlos et al., 2004). Briefly, compounds were diluted in a 23 reaction buf...More data for this Ligand-Target Pair
Affinity DataIC50: 346nMpH: 7.4 T: 2°CAssay Description:The cytochrome b enzyme assay was adapted from previous studies (Gutierrez-Cirlos et al., 2004). Briefly, compounds were diluted in a 23 reaction buf...More data for this Ligand-Target Pair
Affinity DataIC50: 438nMpH: 7.4 T: 2°CAssay Description:The cytochrome b enzyme assay was adapted from previous studies (Gutierrez-Cirlos et al., 2004). Briefly, compounds were diluted in a 23 reaction buf...More data for this Ligand-Target Pair
Affinity DataIC50: 449nMpH: 7.4 T: 2°CAssay Description:The cytochrome b enzyme assay was adapted from previous studies (Gutierrez-Cirlos et al., 2004). Briefly, compounds were diluted in a 23 reaction buf...More data for this Ligand-Target Pair
Affinity DataIC50: 490nMAssay Description:Inhibition of NOX-2 dependent superoxide generation in PMA-differentiated human PLB-985 cells incubated for 1 hr by WST-1 based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of NOX2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 520nMAssay Description:Inhibition of human NOX2 assessed as reduction in ROS production using lucigenin as substrate in presence of NADPH by chemiluminescence based micropl...More data for this Ligand-Target Pair
Affinity DataIC50: 590nMAssay Description:Inhibition of NOX2 in human PLB-985 cells assessed as inhibition of PMA-induced hydrogen peroxide production pretreated for 15 mins followed by PMA s...More data for this Ligand-Target Pair
Affinity DataIC50: 602nMpH: 7.4 T: 2°CAssay Description:The cytochrome b enzyme assay was adapted from previous studies (Gutierrez-Cirlos et al., 2004). Briefly, compounds were diluted in a 23 reaction buf...More data for this Ligand-Target Pair
Affinity DataIC50: 614nMpH: 7.4 T: 2°CAssay Description:The cytochrome b enzyme assay was adapted from previous studies (Gutierrez-Cirlos et al., 2004). Briefly, compounds were diluted in a 23 reaction buf...More data for this Ligand-Target Pair
Affinity DataIC50: 657nMpH: 7.4 T: 2°CAssay Description:The cytochrome b enzyme assay was adapted from previous studies (Gutierrez-Cirlos et al., 2004). Briefly, compounds were diluted in a 23 reaction buf...More data for this Ligand-Target Pair
Affinity DataIC50: 714nMpH: 7.4 T: 2°CAssay Description:The cytochrome b enzyme assay was adapted from previous studies (Gutierrez-Cirlos et al., 2004). Briefly, compounds were diluted in a 23 reaction buf...More data for this Ligand-Target Pair
Affinity DataIC50: 740nMAssay Description:Inhibition of NOX2 (unknown origin) transfected in HEK293 cells assessed as inhibition of hydrogen peroxide production pe-incubated for 15 mins and m...More data for this Ligand-Target Pair
Affinity DataIC50: 790nMpH: 7.4 T: 2°CAssay Description:The cytochrome b enzyme assay was adapted from previous studies (Gutierrez-Cirlos et al., 2004). Briefly, compounds were diluted in a 23 reaction buf...More data for this Ligand-Target Pair
Affinity DataIC50: 870nMAssay Description:Reactive oxygen produced in whole cells or in membrane preparation of Nox1, Nox3, Nox4, Nox5 and xanthine oxidase and glucose oxidase were determined...More data for this Ligand-Target Pair
Affinity DataIC50: 889nMpH: 7.4 T: 2°CAssay Description:The cytochrome b enzyme assay was adapted from previous studies (Gutierrez-Cirlos et al., 2004). Briefly, compounds were diluted in a 23 reaction buf...More data for this Ligand-Target Pair
Affinity DataIC50: 891nMpH: 7.4 T: 2°CAssay Description:The cytochrome b enzyme assay was adapted from previous studies (Gutierrez-Cirlos et al., 2004). Briefly, compounds were diluted in a 23 reaction buf...More data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Reactive oxygen produced in whole cells or in membrane preparation of Nox1, Nox3, Nox4, Nox5 and xanthine oxidase and glucose oxidase were determined...More data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Reactive oxygen produced in whole cells or in membrane preparation of Nox1, Nox3, Nox4, Nox5 and xanthine oxidase and glucose oxidase were determined...More data for this Ligand-Target Pair
Affinity DataIC50: 910nMAssay Description:Inhibition of human NOX2 assessed as reduction in ROS production using lucigenin as substrate in presence of NADPH by chemiluminescence based micropl...More data for this Ligand-Target Pair
Affinity DataIC50: 935nMpH: 7.4 T: 2°CAssay Description:The cytochrome b enzyme assay was adapted from previous studies (Gutierrez-Cirlos et al., 2004). Briefly, compounds were diluted in a 23 reaction buf...More data for this Ligand-Target Pair
Affinity DataIC50: 982nMpH: 7.4 T: 2°CAssay Description:The cytochrome b enzyme assay was adapted from previous studies (Gutierrez-Cirlos et al., 2004). Briefly, compounds were diluted in a 23 reaction buf...More data for this Ligand-Target Pair
Affinity DataIC50: 990nMAssay Description:Inhibition of human NOX2 assessed as reduction in ROS production using lucigenin as substrate in presence of NADPH by chemiluminescence based micropl...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NOX2 (unknown origin) expressed in HEK293T cells assessed as inhibition of PMA-induced superoxide production preincubated for 15 mins f...More data for this Ligand-Target Pair
