Compile Data Set for Download or QSAR
Report error Found 346 Enz. Inhib. hit(s) with Target = 'Cell division cycle 7-related protein kinase/Protein DBF4 homolog A'
LigandPNGBDBM50365700(CHEMBL1958414)
Affinity DataEC50:  60nMAssay Description:Inhibition of CDC7/DBF4-mediated MCM2 phosphorylation in human HCT116 cells after 6 hrs by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50365701(CHEMBL1958415)
Affinity DataEC50:  300nMAssay Description:Inhibition of CDC7/DBF4-mediated MCM2 phosphorylation in human HCT116 cells after 6 hrs by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50365702(CHEMBL1958416)
Affinity DataEC50:  300nMAssay Description:Inhibition of CDC7/DBF4-mediated MCM2 phosphorylation in human HCT116 cells after 6 hrs by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50365703(CHEMBL1958417)
Affinity DataEC50:  2.61E+3nMAssay Description:Inhibition of CDC7/DBF4-mediated MCM2 phosphorylation in human HCT116 cells after 6 hrs by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50365704(CHEMBL1958418)
Affinity DataEC50:  410nMAssay Description:Inhibition of CDC7/DBF4-mediated MCM2 phosphorylation in human HCT116 cells after 6 hrs by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50365705(CHEMBL1958419)
Affinity DataEC50:  1.78E+3nMAssay Description:Inhibition of CDC7/DBF4-mediated MCM2 phosphorylation in human HCT116 cells after 6 hrs by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50365706(CHEMBL1958420)
Affinity DataEC50:  300nMAssay Description:Inhibition of CDC7/DBF4-mediated MCM2 phosphorylation in human HCT116 cells after 6 hrs by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50365708(CHEMBL1958405)
Affinity DataEC50:  60nMAssay Description:Inhibition of CDC7/DBF4-mediated MCM2 phosphorylation in human HCT116 cells after 6 hrs by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50365698(CHEMBL1958411)
Affinity DataEC50:  15nMAssay Description:Inhibition of CDC7/DBF4-mediated MCM2 phosphorylation in human HCT116 cells after 6 hrs by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50365699(CHEMBL1958412)
Affinity DataEC50:  143nMAssay Description:Inhibition of CDC7/DBF4-mediated MCM2 phosphorylation in human HCT116 cells after 6 hrs by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50365709(CHEMBL1958413)
Affinity DataEC50:  180nMAssay Description:Inhibition of CDC7/DBF4-mediated MCM2 phosphorylation in human HCT116 cells after 6 hrs by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50253706(CHEMBL4083927)
Affinity DataKd:  0.541nMAssay Description:Binding affinity to recombinant human full length Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovir...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
LigandPNGBDBM50253675(CHEMBL4080367)
Affinity DataKd:  2.80nMAssay Description:Binding affinity to recombinant human full length Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovir...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
LigandPNGBDBM50253762(CHEMBL4098392)
Affinity DataKd:  1.30nMAssay Description:Binding affinity to recombinant human full length Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovir...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
LigandPNGBDBM50506348(CHEMBL4436649)
Affinity DataIC50: 0.160nMAssay Description:Inhibition of N-terminal GST-fused full-length human CDC7 (1 to 574 end residues)/DBF4 (1 to 674 residues) expressed in baculovirus expression system...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandPNGBDBM50506358(CHEMBL4462898)
Affinity DataIC50: 0.160nMAssay Description:Inhibition of N-terminal GST-fused full-length human CDC7 (1 to 574 end residues)/DBF4 (1 to 674 residues) expressed in baculovirus expression system...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandPNGBDBM50506350(Simurosertib | Tak 931 | Tak-931)
Affinity DataIC50: 0.260nMAssay Description:Inhibition of N-terminal GST-fused full-length human CDC7 (1 to 574 end residues)/DBF4 (1 to 674 residues) expressed in baculovirus expression system...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandPNGBDBM50506351(CHEMBL4439133)
Affinity DataIC50: 0.410nMAssay Description:Inhibition of N-terminal GST-fused full-length human CDC7 (1 to 574 end residues)/DBF4 (1 to 674 residues) expressed in baculovirus expression system...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandPNGBDBM50506359(CHEMBL4570191)
Affinity DataIC50: 0.430nMAssay Description:Inhibition of N-terminal GST-fused full-length human CDC7 (1 to 574 end residues)/DBF4 (1 to 674 residues) expressed in baculovirus expression system...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandPNGBDBM50506351(CHEMBL4439133)
Affinity DataIC50: 0.440nMAssay Description:Inhibition of N-terminal GST-fused full-length human CDC7 (1 to 574 end residues)/DBF4 (1 to 674 residues) expressed in baculovirus expression system...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandPNGBDBM50506353(CHEMBL4543158)
Affinity DataIC50: 0.530nMAssay Description:Inhibition of N-terminal GST-fused full-length human CDC7 (1 to 574 end residues)/DBF4 (1 to 674 residues) expressed in baculovirus expression system...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandPNGBDBM50506350(Simurosertib | Tak 931 | Tak-931)
Affinity DataIC50: 0.540nMAssay Description:Inhibition of N-terminal GST-fused full-length human CDC7 (1 to 574 end residues)/DBF4 (1 to 674 residues) expressed in baculovirus expression system...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandPNGBDBM50237672(CHEMBL4089159)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant human Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovirus expression syst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2019
Entry Details Article
PubMed
LigandPNGBDBM50506356(CHEMBL4569914)
Affinity DataIC50: 0.610nMAssay Description:Inhibition of N-terminal GST-fused full-length human CDC7 (1 to 574 end residues)/DBF4 (1 to 674 residues) expressed in baculovirus expression system...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandPNGBDBM50443648(CHEMBL3093076)
Affinity DataIC50: 0.690nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin)-mediated MCM2 phosphorylation at Ser53 by protein A amplified luminescent proximity homogeneous assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
LigandPNGBDBM50253706(CHEMBL4083927)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of recombinant human full length Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
LigandPNGBDBM50253706(CHEMBL4083927)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of N-terminal GST-fused full-length human CDC7 (1 to 574 end residues)/DBF4 (1 to 674 residues) expressed in baculovirus expression system...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandPNGBDBM50506362(CHEMBL4440266)
Affinity DataIC50: 0.710nMAssay Description:Inhibition of N-terminal GST-fused full-length human CDC7 (1 to 574 end residues)/DBF4 (1 to 674 residues) expressed in baculovirus expression system...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandPNGBDBM50506359(CHEMBL4570191)
Affinity DataIC50: 0.720nMAssay Description:Inhibition of N-terminal GST-fused full-length human CDC7 (1 to 574 end residues)/DBF4 (1 to 674 residues) expressed in baculovirus expression system...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandPNGBDBM50443649(CHEMBL3093075)
Affinity DataIC50: 0.850nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin)-mediated MCM2 phosphorylation at Ser53 by protein A amplified luminescent proximity homogeneous assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
LigandPNGBDBM50506347(CHEMBL4587191)
Affinity DataIC50: 0.910nMAssay Description:Inhibition of N-terminal GST-fused full-length human CDC7 (1 to 574 end residues)/DBF4 (1 to 674 residues) expressed in baculovirus expression system...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandPNGBDBM50443650(CHEMBL3093074)
Affinity DataIC50: 1nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin)-mediated MCM2 phosphorylation at Ser53 by protein A amplified luminescent proximity homogeneous assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
LigandPNGBDBM50380229(CHEMBL2016996)
Affinity DataIC50: 1nMAssay Description:Inhibition of CDC7/DBF4 using MCM-2 as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50380230(CHEMBL2016862)
Affinity DataIC50: 1nMAssay Description:Inhibition of CDC7/DBF4 using MCM-2 as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50380236(CHEMBL2016856)
Affinity DataIC50: 1nMAssay Description:Inhibition of CDC7/DBF4 using MCM-2 as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50450841(CHEMBL4214023)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human Cdc7 (1 to 574 residues)/human N-terminal GST-tagged DBF4 (1 to 674 residues) expressed in baculovirus expression sys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandPNGBDBM50506361(CHEMBL4572218)
Affinity DataIC50: 1nMAssay Description:Inhibition of N-terminal GST-fused full-length human CDC7 (1 to 574 end residues)/DBF4 (1 to 674 residues) expressed in baculovirus expression system...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandPNGBDBM50443644(CHEMBL3093080)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin)-mediated MCM2 phosphorylation at Ser53 by protein A amplified luminescent proximity homogeneous assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
LigandPNGBDBM50253676(CHEMBL4087760)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of recombinant human full length Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
LigandPNGBDBM50450842(CHEMBL4213805)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of recombinant human Cdc7 (1 to 574 residues)/human N-terminal GST-tagged DBF4 (1 to 674 residues) expressed in baculovirus expression sys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandPNGBDBM50253759(CHEMBL4078941)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of recombinant human full length Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
LigandPNGBDBM50506354(CHEMBL4529213)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of N-terminal GST-fused full-length human CDC7 (1 to 574 end residues)/DBF4 (1 to 674 residues) expressed in baculovirus expression system...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandPNGBDBM50506360(CHEMBL4462574)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of N-terminal GST-fused full-length human CDC7 (1 to 574 end residues)/DBF4 (1 to 674 residues) expressed in baculovirus expression system...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandPNGBDBM50253708(CHEMBL4070822)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of recombinant human full length Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
LigandPNGBDBM50443646(CHEMBL3093078)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin)-mediated MCM2 phosphorylation at Ser53 by protein A amplified luminescent proximity homogeneous assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
LigandPNGBDBM50450844(CHEMBL4216005)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of recombinant human Cdc7 (1 to 574 residues)/human N-terminal GST-tagged DBF4 (1 to 674 residues) expressed in baculovirus expression sys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandPNGBDBM50253702(CHEMBL4080673)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of recombinant human full length Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
LigandPNGBDBM50253753(CHEMBL4062209)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of recombinant human full length Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
LigandPNGBDBM50253677(CHEMBL4095460)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of recombinant human full length Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
LigandPNGBDBM50253706(CHEMBL4083927)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of recombinant human full length Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
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