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Report error Found 213 Enz. Inhib. hit(s) with Target = 'Casein kinase II subunit alpha 3'
TargetCasein kinase II subunit alpha 3(Human)
University of Lyon

Curated by ChEMBL
LigandPNGBDBM50530315(CHEMBL4520531)
Affinity DataEC50:  1.60E+3nMAssay Description:Inhibition of CK2 in human 786-0 cells assessed as reduction in STAT3 phosphorylation at Y705 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha 3(Human)
University of Lyon

Curated by ChEMBL
LigandPNGBDBM50530315(CHEMBL4520531)
Affinity DataEC50:  4.00E+3nMAssay Description:Inhibition of CK2 in human 786-0 cells assessed as decrease in p21 phosphorylation at Thr145 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha 3(Human)
University of Lyon

Curated by ChEMBL
LigandPNGBDBM50530315(CHEMBL4520531)
Affinity DataEC50:  3.20E+3nMAssay Description:Inhibition of CK2 in human 786-0 cells assessed as decrease in Akt1 phosphorylation at Ser129 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha 3(Human)
University of Lyon

Curated by ChEMBL
LigandPNGBDBM50132260(CHEMBL105442 | US8575391, 341 | CI-1040 | 2-(2-chl...)
Affinity DataEC50:  100nMAssay Description:Inhibition of CK2 in human 786-0 cells assessed as decrease in Akt1 phosphorylation at Ser129 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha 3(Human)
University of Lyon

Curated by ChEMBL
LigandPNGBDBM50530325(CHEMBL4458300)
Affinity DataEC50:  1.60E+4nMAssay Description:Inhibition of CK2 in human 786-0 cells assessed as decrease in Akt1 phosphorylation at Ser129 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha 3(Human)
University of Lyon

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataEC50:  1.00E+3nMAssay Description:Inhibition of CK2 in human 786-0 cells assessed as decrease in alpha-catenin phosphorylation at Ser641 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCasein kinase II subunit alpha 3(Human)
University of Lyon

Curated by ChEMBL
LigandPNGBDBM50530325(CHEMBL4458300)
Affinity DataEC50:  6.00E+3nMAssay Description:Inhibition of CK2 in human 786-0 cells assessed as decrease in alpha-catenin phosphorylation at Ser641 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha 3(Human)
University of Lyon

Curated by ChEMBL
LigandPNGBDBM50530315(CHEMBL4520531)
Affinity DataEC50:  4.30E+3nMAssay Description:Inhibition of CK2 in human 786-0 cells assessed as decrease in alpha-catenin phosphorylation at Ser641 assuming basal level of non-responsive P-alpha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha 3(Human)
University of Lyon

Curated by ChEMBL
LigandPNGBDBM50530315(CHEMBL4520531)
Affinity DataEC50:  4.30E+3nMAssay Description:Inhibition of CK2 in human 786-0 cells assessed as decrease in alpha-catenin phosphorylation at Ser641 assuming basal level of non-responsive P-alpha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha 3(Human)
University of Lyon

Curated by ChEMBL
LigandPNGBDBM50530325(CHEMBL4458300)
Affinity DataEC50:  1.60E+4nMAssay Description:Inhibition of CK2 in human 786-0 cells assessed as decrease in Akt1 phosphorylation at Ser129 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha 3(Human)
University of Lyon

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataEC50:  1.00E+3nMAssay Description:Inhibition of CK2 in human 786-0 cells assessed as decrease in alpha-catenin phosphorylation at Ser641 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCasein kinase II subunit alpha 3(Human)
University of Lyon

Curated by ChEMBL
LigandPNGBDBM50530325(CHEMBL4458300)
Affinity DataEC50:  6.00E+3nMAssay Description:Inhibition of CK2 in human 786-0 cells assessed as decrease in alpha-catenin phosphorylation at Ser641 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha 3(Human)
University of Lyon

Curated by ChEMBL
LigandPNGBDBM50530315(CHEMBL4520531)
Affinity DataEC50:  1.60E+3nMAssay Description:Inhibition of CK2 in human 786-0 cells assessed as reduction in STAT3 phosphorylation at Y705 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha 3(Human)
University of Lyon

Curated by ChEMBL
LigandPNGBDBM50530315(CHEMBL4520531)
Affinity DataEC50:  9.00E+3nMAssay Description:Inhibition of CK2 in human 786-0 cells assessed as decrease in alpha-catenin phosphorylation at Ser641 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha 3(Human)
University of Lyon

Curated by ChEMBL
LigandPNGBDBM50132260(CHEMBL105442 | US8575391, 341 | CI-1040 | 2-(2-chl...)
Affinity DataEC50:  100nMAssay Description:Inhibition of CK2 in human 786-0 cells assessed as decrease in Akt1 phosphorylation at Ser129 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha 3(Human)
University of Lyon

Curated by ChEMBL
LigandPNGBDBM50530315(CHEMBL4520531)
Affinity DataEC50:  9.00E+3nMAssay Description:Inhibition of CK2 in human 786-0 cells assessed as decrease in alpha-catenin phosphorylation at Ser641 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha 3(Human)
University of Lyon

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataEC50:  5.30E+3nMAssay Description:Inhibition of CK2 in human 786-0 cells assessed as reduction in STAT3 phosphorylation at Y705 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCasein kinase II subunit alpha 3(Human)
University of Lyon

Curated by ChEMBL
LigandPNGBDBM50530315(CHEMBL4520531)
Affinity DataEC50:  3.20E+3nMAssay Description:Inhibition of CK2 in human 786-0 cells assessed as decrease in Akt1 phosphorylation at Ser129 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha 3(Human)
University of Lyon

Curated by ChEMBL
LigandPNGBDBM50530315(CHEMBL4520531)
Affinity DataEC50:  4.00E+3nMAssay Description:Inhibition of CK2 in human 786-0 cells assessed as decrease in p21 phosphorylation at Thr145 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha 3(Human)
University of Lyon

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataEC50:  5.30E+3nMAssay Description:Inhibition of CK2 in human 786-0 cells assessed as reduction in STAT3 phosphorylation at Y705 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCasein kinase II subunit alpha 3(Human)
University of Lyon

Curated by ChEMBL
LigandPNGBDBM50461966(CHEMBL4117419)
Affinity DataKd:  2.67E+5nMAssay Description:Binding affinity to CK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCasein kinase II subunit alpha 3(Human)
University of Lyon

Curated by ChEMBL
LigandPNGBDBM50461965(CHEMBL4224990)
Affinity DataKd:  1.70E+4nMAssay Description:Binding affinity to CK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCasein kinase II subunit alpha 3(Human)
University of Lyon

Curated by ChEMBL
LigandPNGBDBM50632204(CHEMBL5408174)
Affinity DataKd:  5.80E+4nMAssay Description:Binding affinity to CK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCasein kinase II subunit alpha 3(Human)
University of Lyon

Curated by ChEMBL
LigandPNGBDBM50632208(CHEMBL5409566)
Affinity DataKd:  560nMAssay Description:Binding affinity to CK2 (unknown origin) by ITC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCasein kinase II subunit alpha 3(Human)
University of Lyon

Curated by ChEMBL
LigandPNGBDBM50566490(CHEMBL4848224)
Affinity DataIC50: 0.230nMAssay Description:Inhibition of human CK2 incubated for 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha 3(Human)
University of Lyon

Curated by ChEMBL
LigandPNGBDBM50566482(CHEMBL4862003)
Affinity DataIC50: 0.460nMAssay Description:Inhibition of human CK2 incubated for 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha 3(Human)
University of Lyon

Curated by ChEMBL
LigandPNGBDBM50566492(CHEMBL4872225)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human CK2 incubated for 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha 3(Human)
University of Lyon

Curated by ChEMBL
LigandPNGBDBM50566488(CHEMBL4875513)
Affinity DataIC50: 0.610nMAssay Description:Inhibition of human CK2 incubated for 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha 3(Human)
University of Lyon

Curated by ChEMBL
LigandPNGBDBM50566473(CHEMBL4860630)
Affinity DataIC50: 0.660nMAssay Description:Inhibition of human CK2 incubated for 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha 3(Human)
University of Lyon

Curated by ChEMBL
LigandPNGBDBM50566489(CHEMBL4848072)
Affinity DataIC50: 0.760nMAssay Description:Inhibition of human CK2 incubated for 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha 3(Human)
University of Lyon

Curated by ChEMBL
LigandPNGBDBM50566479(CHEMBL4875815)
Affinity DataIC50: 0.790nMAssay Description:Inhibition of human CK2 incubated for 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha 3(Human)
University of Lyon

Curated by ChEMBL
LigandPNGBDBM50566474(CHEMBL4878998)
Affinity DataIC50: 0.890nMAssay Description:Inhibition of human CK2 incubated for 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha 3(Human)
University of Lyon

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human CK2 incubated for 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCasein kinase II subunit alpha 3(Human)
University of Lyon

Curated by ChEMBL
LigandPNGBDBM50539771(CHEMBL4649511)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human recombinant CK2 using RRRDDDSDDD peptide as substrate preincubated for 30 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha 3(Human)
University of Lyon

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human recombinant CK2 using RRRDDDSDDD peptide as substrate preincubated for 30 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCasein kinase II subunit alpha 3(Human)
University of Lyon

Curated by ChEMBL
LigandPNGBDBM50566475(CHEMBL4857079)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human CK2 incubated for 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha 3(Human)
University of Lyon

Curated by ChEMBL
LigandPNGBDBM165355(US9062043, Table 20b, Compound 15 | US9062043, Tab...)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of CK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCasein kinase II subunit alpha 3(Human)
University of Lyon

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50: 3nMAssay Description:Inhibition of CK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCasein kinase II subunit alpha 3(Human)
University of Lyon

Curated by ChEMBL
LigandPNGBDBM50609381(CHEMBL5276409)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of recombinant human CK2 using RRRDDDSDDD as substrate in presence of [gamma-33P-ATP] incubated for 20 mins by beta-counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetCasein kinase II subunit alpha 3(Human)
University of Lyon

Curated by ChEMBL
LigandPNGBDBM50566493(CHEMBL4857107)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of human CK2 incubated for 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha 3(Human)
University of Lyon

Curated by ChEMBL
LigandPNGBDBM50539769(CHEMBL4637423)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human recombinant CK2 using RRRDDDSDDD peptide as substrate preincubated for 30 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha 3(Human)
University of Lyon

Curated by ChEMBL
LigandPNGBDBM50566485(CHEMBL4867054)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of human CK2 incubated for 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha 3(Human)
University of Lyon

Curated by ChEMBL
LigandPNGBDBM50566484(CHEMBL4866502)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of human CK2 incubated for 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha 3(Human)
University of Lyon

Curated by ChEMBL
LigandPNGBDBM50566471(CHEMBL4855171)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of human CK2 incubated for 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha 3(Human)
University of Lyon

Curated by ChEMBL
LigandPNGBDBM50632206(CHEMBL4847656)
Affinity DataIC50: 7nMAssay Description:Inhibition of CK2 (unknown origin) incubated for 1.5 hrs in presence of ATP by kinase-glo luminescent kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCasein kinase II subunit alpha 3(Human)
University of Lyon

Curated by ChEMBL
LigandPNGBDBM50566491(CHEMBL4849246)
Affinity DataIC50: 7.30nMAssay Description:Inhibition of human CK2 incubated for 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha 3(Human)
University of Lyon

Curated by ChEMBL
LigandPNGBDBM50566483(CHEMBL4873444)
Affinity DataIC50: 8.80nMAssay Description:Inhibition of human CK2 incubated for 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha 3(Human)
University of Lyon

Curated by ChEMBL
LigandPNGBDBM50632203(CHEMBL5421618)
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant CK2 using RRRDDDSDDD peptide as substrate incubated for 20 mins in presence of [gamma-32p]-ATP and ATP by beta-counte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCasein kinase II subunit alpha 3(Human)
University of Lyon

Curated by ChEMBL
LigandPNGBDBM165396(US9062043, Table 20b, Compound 29 | US9062043, Tab...)
Affinity DataIC50: 9.10nMAssay Description:Inhibition of CK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCasein kinase II subunit alpha 3(Human)
University of Lyon

Curated by ChEMBL
LigandPNGBDBM50566472(CHEMBL4854640)
Affinity DataIC50: 9.30nMAssay Description:Inhibition of human CK2 incubated for 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
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