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Report error Found 103 Enz. Inhib. hit(s) with Target = 'Calcium-activated potassium channel subunit alpha-1'
TargetCalcium-activated potassium channel subunit alpha-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50128973(2-Dimethylamino-1H-pyrrolo[3,2-b]pyridine-3-carbon...)
Affinity DataEC50:  5.13E+3nMAssay Description:[86Rb+] efflux induced by BKca alpha subunits expressed in HEK293 cells at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcium-activated potassium channel subunit alpha-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50128974(2-Azepan-1-yl-1H-pyrrolo[3,2-b]pyridine-3-carbonit...)
Affinity DataEC50:  3.34E+3nMAssay Description:[86Rb+] efflux induced by BKca alpha subunits expressed in HEK293 cells at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcium-activated potassium channel subunit alpha-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50128976(2-(4-Hydroxy-piperidin-1-yl)-1H-pyrrolo[3,2-b]pyri...)
Affinity DataEC50:  1.51E+4nMAssay Description:[86Rb+] efflux induced by BKca alpha subunits expressed in HEK293 cells at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcium-activated potassium channel subunit alpha-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50128977(2-Hydroxy-1H-pyrrolo[3,2-b]pyridine-3-carbonitrile...)
Affinity DataEC50:  1.34E+4nMAssay Description:[86Rb+] efflux induced by BKca alpha subunits expressed in HEK293 cells at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcium-activated potassium channel subunit alpha-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50128979(2-(3-Aza-bicyclo[3.2.2]non-3-yl)-1H-pyrrolo[3,2-b]...)
Affinity DataEC50:  4.43E+3nMAssay Description:[86Rb+] efflux induced by BKca alpha subunits expressed in HEK293 cells at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcium-activated potassium channel subunit alpha-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50128978(2-Imidazol-1-yl-1H-pyrrolo[3,2-b]pyridine-3-carbon...)
Affinity DataEC50:  5.86E+3nMAssay Description:[86Rb+] efflux induced by BKca alpha subunits expressed in HEK293 cells at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcium-activated potassium channel subunit alpha-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50128980(2-Pyrrolidin-1-yl-1H-pyrrolo[3,2-b]pyridine-3-carb...)
Affinity DataEC50:  8.12E+3nMAssay Description:[86Rb+] efflux induced by BKca alpha subunits expressed in HEK293 cells at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcium-activated potassium channel subunit alpha-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50128981(1-(3-Cyano-1H-pyrrolo[3,2-b]pyridin-2-yl)-piperidi...)
Affinity DataEC50:  1.70E+4nMAssay Description:[86Rb+] efflux induced by BKca alpha subunits expressed in HEK293 cells at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcium-activated potassium channel subunit alpha-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50128982(2-Diethylamino-1H-pyrrolo[3,2-b]pyridine-3-carboni...)
Affinity DataEC50:  6.94E+3nMAssay Description:[86Rb+] efflux induced by BKca alpha subunits expressed in HEK293 cells at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcium-activated potassium channel subunit alpha-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50128975(2-((S)-3-Hydroxy-piperidin-1-yl)-1H-pyrrolo[3,2-b]...)
Affinity DataEC50:  5.07E+3nMAssay Description:[86Rb+] efflux induced by BKca alpha subunits expressed in HEK293 cells at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcium-activated potassium channel subunit alpha-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50128984(2-[(2-Dimethylamino-ethyl)-methyl-amino]-1H-pyrrol...)
Affinity DataEC50:  6.75E+3nMAssay Description:[86Rb+] efflux induced by BKca alpha subunits expressed in HEK293 cells at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcium-activated potassium channel subunit alpha-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50128985(2-Morpholin-4-yl-1H-pyrrolo[3,2-b]pyridine-3-carbo...)
Affinity DataEC50:  3.86E+3nMAssay Description:[86Rb+] efflux induced by BKca alpha subunits expressed in HEK293 cells at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcium-activated potassium channel subunit alpha-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50426567(BMS-204352 | MaxiPost | FLINDOKALNER)
Affinity DataEC50:  352nMAssay Description:Positive modulation of Kca 1.1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCalcium-activated potassium channel subunit alpha-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50593373(CHEMBL5182581)
Affinity DataEC50: >3.00E+4nMAssay Description:Activation of Maxi-K channel (unknown origin) by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCalcium-activated potassium channel subunit alpha-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412627(CHEMBL445346)
Affinity DataIC50: 3.24nMAssay Description:Activation of BK channel-mediated vasorelaxation activity assessed as reduction in KCl-induced contractile toneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetCalcium-activated potassium channel subunit alpha-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412628(CHEMBL448335)
Affinity DataIC50: 27.5nMAssay Description:Activation of BK channel-mediated vasorelaxation activity assessed as reduction in KCl-induced contractile toneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetCalcium-activated potassium channel subunit alpha-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412629(CHEMBL465922)
Affinity DataIC50: 27.5nMAssay Description:Activation of BK channel-mediated vasorelaxation activity assessed as reduction in KCl-induced contractile toneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetCalcium-activated potassium channel subunit alpha-1(Rat)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50412339(CHEMBL496460)
Affinity DataIC50: 39.8nMAssay Description:Activation of large-conductance calcium-activated potassium channel-mediated vasorelaxation in endothelium-denuded normotensive Wistar rat thoracic a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetCalcium-activated potassium channel subunit alpha-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412630(CHEMBL524902)
Affinity DataIC50: 135nMAssay Description:Activation of BK channel-mediated vasorelaxation activity assessed as reduction in KCl-induced contractile toneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetCalcium-activated potassium channel subunit alpha-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412631(CHEMBL504160)
Affinity DataIC50: 145nMAssay Description:Activation of BK channel-mediated vasorelaxation activity assessed as reduction in KCl-induced contractile toneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetCalcium-activated potassium channel subunit alpha-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412632(CHEMBL511200)
Affinity DataIC50: 178nMAssay Description:Activation of BK channel-mediated vasorelaxation activity assessed as reduction in KCl-induced contractile toneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetCalcium-activated potassium channel subunit alpha-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412633(CHEMBL506373)
Affinity DataIC50: 191nMAssay Description:Activation of BK channel-mediated vasorelaxation activity assessed as reduction in KCl-induced contractile toneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetCalcium-activated potassium channel subunit alpha-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412682(CHEMBL464057)
Affinity DataIC50: 251nMAssay Description:Activation of BK channel-mediated vasorelaxation activity assessed as reduction in KCl-induced contractile toneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetCalcium-activated potassium channel subunit alpha-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50318484(CHEMBL190461 | 2-((1R,6R)-6-Isopropenyl-3-methyl-c...)
Affinity DataIC50: 280nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCalcium-activated potassium channel subunit alpha-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412634(CHEMBL517012)
Affinity DataIC50: 282nMAssay Description:Activation of BK channel-mediated vasorelaxation activity assessed as reduction in KCl-induced contractile toneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetCalcium-activated potassium channel subunit alpha-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412635(CHEMBL455306)
Affinity DataIC50: 372nMAssay Description:Activation of BK channel-mediated vasorelaxation activity assessed as reduction in KCl-induced contractile toneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetCalcium-activated potassium channel subunit alpha-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412636(CHEMBL453712)
Affinity DataIC50: 447nMAssay Description:Activation of BK channel-mediated vasorelaxation activity assessed as reduction in KCl-induced contractile toneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetCalcium-activated potassium channel subunit alpha-1(Rat)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50412337(CHEMBL498516)
Affinity DataIC50: 617nMAssay Description:Activation of large-conductance calcium-activated potassium channel-mediated vasorelaxation in endothelium-denuded normotensive Wistar rat thoracic a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetCalcium-activated potassium channel subunit alpha-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412637(CHEMBL465950)
Affinity DataIC50: 646nMAssay Description:Activation of BK channel-mediated vasorelaxation activity assessed as reduction in KCl-induced contractile toneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetCalcium-activated potassium channel subunit alpha-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412638(TCMDC-124051 | CHEMBL464249)
Affinity DataIC50: 692nMAssay Description:Activation of BK channel-mediated vasorelaxation activity assessed as reduction in KCl-induced contractile toneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetCalcium-activated potassium channel subunit alpha-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412639(CHEMBL465109)
Affinity DataIC50: 1.45E+3nMAssay Description:Activation of BK channel-mediated vasorelaxation activity assessed as reduction in KCl-induced contractile toneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetCalcium-activated potassium channel subunit alpha-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412640(CHEMBL465454)
Affinity DataIC50: 1.55E+3nMAssay Description:Activation of BK channel-mediated vasorelaxation activity assessed as reduction in KCl-induced contractile toneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetCalcium-activated potassium channel subunit alpha-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412641(CHEMBL512408)
Affinity DataIC50: 2.14E+3nMAssay Description:Activation of BK channel-mediated vasorelaxation activity assessed as reduction in KCl-induced contractile toneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetCalcium-activated potassium channel subunit alpha-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412642(CHEMBL465455)
Affinity DataIC50: 2.45E+3nMAssay Description:Activation of BK channel-mediated vasorelaxation activity assessed as reduction in KCl-induced contractile toneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetCalcium-activated potassium channel subunit alpha-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412643(CHEMBL499800)
Affinity DataIC50: 2.51E+3nMAssay Description:Activation of BK channel-mediated vasorelaxation activity assessed as reduction in KCl-induced contractile toneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetCalcium-activated potassium channel subunit alpha-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412644(CHEMBL465456)
Affinity DataIC50: 2.63E+3nMAssay Description:Activation of BK channel-mediated vasorelaxation activity assessed as reduction in KCl-induced contractile toneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetCalcium-activated potassium channel subunit alpha-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412645(CHEMBL526140)
Affinity DataIC50: 3.02E+3nMAssay Description:Activation of BK channel-mediated vasorelaxation activity assessed as reduction in KCl-induced contractile toneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetCalcium-activated potassium channel subunit alpha-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412646(CHEMBL481576)
Affinity DataIC50: 3.09E+3nMAssay Description:Activation of BK channel-mediated vasorelaxation activity assessed as reduction in KCl-induced contractile toneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetCalcium-activated potassium channel subunit alpha-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM67581(N-(5-chloranyl-2-oxidanyl-phenyl)-2-ethoxy-benzami...)
Affinity DataIC50: 3.09E+3nMAssay Description:Activation of BK channel-mediated vasorelaxation activity assessed as reduction in KCl-induced contractile toneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetCalcium-activated potassium channel subunit alpha-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412647(CHEMBL481578)
Affinity DataIC50: 3.31E+3nMAssay Description:Activation of BK channel-mediated vasorelaxation activity assessed as reduction in KCl-induced contractile toneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetCalcium-activated potassium channel subunit alpha-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412648(CHEMBL519785)
Affinity DataIC50: 3.47E+3nMAssay Description:Activation of BK channel-mediated vasorelaxation activity assessed as reduction in KCl-induced contractile toneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetCalcium-activated potassium channel subunit alpha-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412649(CHEMBL480795)
Affinity DataIC50: 4.07E+3nMAssay Description:Activation of BK channel-mediated vasorelaxation activity assessed as reduction in KCl-induced contractile toneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetCalcium-activated potassium channel subunit alpha-1(Rat)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50347497(CHEMBL384903)
Affinity DataIC50: 4.37E+3nMAssay Description:Induction of BK channel mediated vasorelaxation activity in Kcl-induced contraction in Wistar rat aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetCalcium-activated potassium channel subunit alpha-1(Rat)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50347497(CHEMBL384903)
Affinity DataIC50: 5.01E+3nMAssay Description:Activation of large-conductance calcium-activated potassium channel-mediated vasorelaxation in endothelium-denuded normotensive Wistar rat thoracic a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetCalcium-activated potassium channel subunit alpha-1(Rat)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50347497(CHEMBL384903)
Affinity DataIC50: 5.13E+3nMAssay Description:Activation of BK channel in Wistar rat thoracic aorta assessed as relaxation of KCl-induced contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetCalcium-activated potassium channel subunit alpha-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412650(CHEMBL297914)
Affinity DataIC50: 5.25E+3nMAssay Description:Activation of BK channel-mediated vasorelaxation activity assessed as reduction in KCl-induced contractile toneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetCalcium-activated potassium channel subunit alpha-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412651(CHEMBL482376)
Affinity DataIC50: 5.89E+3nMAssay Description:Activation of BK channel-mediated vasorelaxation activity assessed as reduction in KCl-induced contractile toneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetCalcium-activated potassium channel subunit alpha-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50347497(CHEMBL384903)
Affinity DataIC50: 5.89E+3nMAssay Description:Activation of BK channel-mediated vasorelaxation activity assessed as reduction in KCl-induced contractile toneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetCalcium-activated potassium channel subunit alpha-1(Rat)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50412335(CHEMBL498702)
Affinity DataIC50: 6.31E+3nMAssay Description:Activation of large-conductance calcium-activated potassium channel-mediated vasorelaxation in endothelium-denuded normotensive Wistar rat thoracic a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetCalcium-activated potassium channel subunit alpha-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412652(CHEMBL482377)
Affinity DataIC50: 6.92E+3nMAssay Description:Activation of BK channel-mediated vasorelaxation activity assessed as reduction in KCl-induced contractile toneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
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