Report error Found 1730 Enz. Inhib. hit(s) with Target = 'Calcitonin gene-related peptide type 1 receptor'
Affinity DataEC50: 0.0260nMAssay Description:Antagonist activity at CGRP receptor in human SK-N-MC cells assessed as inhibition of alpha-CGRP-induced c-AMP formation after 15 mins by radioimmuno...More data for this Ligand-Target Pair
Affinity DataEC50: 0.150nMAssay Description:Antagonist activity at CGRP receptor in human SK-N-MC cells assessed as inhibition of alpha-CGRP-induced c-AMP formation after 15 mins by radioimmuno...More data for this Ligand-Target Pair
Affinity DataEC50: 96nMAssay Description:Antagonist activity at CGRP receptor in human SK-N-MC cells assessed as inhibition of alpha-CGRP-induced c-AMP formation after 15 mins by radioimmuno...More data for this Ligand-Target Pair
Affinity DataEC50: 100nMAssay Description:Antagonist activity at CGRP receptor in human SK-N-MC cells assessed as inhibition of alpha-CGRP-induced c-AMP formation after 15 mins by radioimmuno...More data for this Ligand-Target Pair
Affinity DataKd: 1.90nMAssay Description:Reversible saturable binding affinity to human CGRP receptor using [3H]-labeled compoundMore data for this Ligand-Target Pair
Affinity DataEC50: 0.200nMAssay Description:Agonist activity at human CGRP1 expressed in HEK293 cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0345nMAssay Description:Antagonist activity at human CGRP receptor in SK-N-MC cells assessed as inhibition of CGRP-stimulated cAMP productionMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0170nMAssay Description:Antagonist activity at CGRP receptor in human SK-N-MC cells assessed as inhibition of CCRP-induced cAMP productionMore data for this Ligand-Target Pair
Affinity DataEC50: 0.140nMAssay Description:Antagonist activity at CGRP receptor in human SK-N-MC cells assessed as inhibition of CGRP-stimulated cAMP production preincubated for 15 mins prior ...More data for this Ligand-Target Pair
Affinity DataEC50: 12nMAssay Description:Antagonist activity at CGRP receptor in human SK-N-MC cells assessed as inhibition of CGRP-stimulated formation of cyclic AMPMore data for this Ligand-Target Pair
Affinity DataEC50: 15nMAssay Description:Antagonist activity at CGRP receptor in human SK-N-MC cells assessed as inhibition of CGRP-stimulated formation of cyclic AMPMore data for this Ligand-Target Pair
Affinity DataEC50: 130nMAssay Description:Antagonist activity at CGRP receptor in human SK-N-MC cells assessed as inhibition of CGRP-stimulated formation of cyclic AMPMore data for this Ligand-Target Pair
Affinity DataEC50: 13nMAssay Description:Antagonist activity at CGRP receptor in human SK-N-MC cells assessed as inhibition of CGRP-stimulated formation of cyclic AMPMore data for this Ligand-Target Pair
Affinity DataEC50: 31nMAssay Description:Antagonist activity at CGRP receptor in human SK-N-MC cells assessed as inhibition of CGRP-stimulated formation of cyclic AMPMore data for this Ligand-Target Pair
Affinity DataEC50: 3nMAssay Description:Antagonist activity at CGRP receptor in human SK-N-MC cells assessed as inhibition of CGRP-stimulated formation of cyclic AMPMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0100nMAssay Description:Antagonist activity at human cloned CGRP receptor expressed in mouse E10 cells assessed as inhibition of CGRP-induced cAMP productionMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0100nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0100nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0100nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0100nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0100nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Human)
Biohaven Pharmaceuticals
Curated by ChEMBL
Biohaven Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of human CLR/RAMP1 by cAMP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0110nMAssay Description:Antagonist activity at human cloned CGRP receptor expressed in mouse E10 cells assessed as inhibition of CGRP-induced cAMP productionMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0170nMAssay Description:Antagonist activity at human cloned CGRP receptor expressed in mouse E10 cells assessed as inhibition of CGRP-induced cAMP productionMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0190nMAssay Description:Antagonist activity at human CGRP receptor expressed in human SK-N-MC cells assessed as inhibition of CGRP-stimulated cAMP productionMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:Antagonist activity at human cloned CGRP receptor expressed in mouse E10 cells assessed as inhibition of CGRP-induced cAMP productionMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:Antagonist activity at CGRP receptor in human SK-N-MC cells assessed as inhibition of CGRP-stimulated cAMP productionMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:Displacement of [125I]CGRP from CGRP receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0220nMAssay Description:Antagonist activity at human cloned CGRP receptor expressed in mouse E10 cells assessed as inhibition of CGRP-induced cAMP productionMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0260nMAssay Description:Antagonist activity at human CGRP receptor expressed in human SK-N-MC cells assessed as inhibition of CGRP-stimulated cAMP productionMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0300nMAssay Description:Antagonist activity against human CGRP receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0300nMpH: 7.4Assay Description:Affinity against human calcitonin gene related peptide receptor (1 uM) expressed in SK-N-MC cells using [125I]-CGRP as radioligand after 180 minutes ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0300nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0300nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0300nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0300nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
