Compile Data Set for Download or QSAR
Report error Found 1490 Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4 [342-460]'
TargetBromodomain-containing protein 4 [342-460](Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM552061(US11312726, Compound 32 | US12344620, Compound of ...)
Affinity DataIC50: 10nMAssay Description:1) using BRD4-BD1 protein and BRD4-BD2 protein from BPS company for the experiments; as well as polypeptides from ANASPEC company; detection reagents...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM543516(US11279703, TABLE 6.37 | US11279703, TABLE 6.199 |...)
Affinity DataIC50: 13nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM50365262(CHEMBL1957266 | (S)-JQ1 (1) | US9320741, (S)-JQ1 |...)
Affinity DataIC50: 21nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM362674(US9834565, Example 29 | (4S)-7-(3,5-dimethylisoxaz...)
Affinity DataIC50: 25nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM362673(US9834565, Example 28 | (4S)-2-[4-(cyclobutylcarbo...)
Affinity DataIC50: 25nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM438727(N-{1-[(4S)-7-(3,5-dimethylisoxazol-4-yl)- 4-pyridi...)
Affinity DataIC50: 25nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM438728((4S)-2-[(3S)-4-acetyl-3-methylpiperazin-1- yl]-7-(...)
Affinity DataIC50: 25nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM362642(US9834565, Example 4 | (4S)-2-(5-acetyl-2,5- diaza...)
Affinity DataIC50: 25nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM438726(N-{1-[(4S)-7-(3,5-dimethylisoxazol-4-yl)- 4-pyridi...)
Affinity DataIC50: 25nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM362504((4S)-2-[(2R,6S)-4-Acetyl-2,6-dimethylpiperazin-1-y...)
Affinity DataIC50: 25nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM362565((4S)-2-[(2S)-4-acetyl-2-methylpiperazin-1- yl]-7-(...)
Affinity DataIC50: 25nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM362428((4S)-7-(3,5-Dimethylisoxazol-4-yl)-2-(4-isobutyryl...)
Affinity DataIC50: 25nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM318710(US9624241, Example 240 | N-{1-[(4S)-7-(3,5-dimethy...)
Affinity DataIC50: 25nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM438736(N-{1-[(4S)-7-(3,5-dimethylisoxazol-4-yl)- 4-pyridi...)
Affinity DataIC50: 25nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM362504((4S)-2-[(2R,6S)-4-Acetyl-2,6-dimethylpiperazin-1-y...)
Affinity DataIC50: 25nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM438733(N-{1-[(4S)-7-(3,5-dimethylisoxazol-4-yl)- 4-pyridi...)
Affinity DataIC50: 25nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM362428((4S)-7-(3,5-Dimethylisoxazol-4-yl)-2-(4-isobutyryl...)
Affinity DataIC50: 25nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM438734(N-{1-[(4S)-7-(3,5-dimethylisoxazol-4-yl)- 4-pyridi...)
Affinity DataIC50: 25nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM438731(N-{1-[(4S)-7-(3,5-dimethylisoxazol-4-yl)- 4-pyridi...)
Affinity DataIC50: 25nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM438732(N-{1-[(4S)-7-(3,5-dimethylisoxazol-4-yl)- 4-pyridi...)
Affinity DataIC50: 25nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM438729((4S)-7-(3,5-dimethylisoxazol-4-yl)-2-[(3S)- 3-meth...)
Affinity DataIC50: 25nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM438730((4S)-7-(3,5-dimethylisoxazol-4-yl)-2-[(3S)- 4-isob...)
Affinity DataIC50: 25nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM362653(US9834565, Example 8 | (4S)-7-(3,5-dimethylisoxazo...)
Affinity DataIC50: 25nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM438743(N-{1-[(4S)-7-(3,5-dimethylisoxazol-4-yl)- 4-pyridi...)
Affinity DataIC50: 25nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM362652(US9834565, Example 7 | (4S)-2-[(3S)-4-acetyl-3-met...)
Affinity DataIC50: 25nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM438744(N-{1-[(4S)-7-(3,5-dimethylisoxazol-4-yl)- 4-pyridi...)
Affinity DataIC50: 25nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM362655(US9834565, Example 10 | N-{1-[(4S)-7-(3,5-dimethyl...)
Affinity DataIC50: 25nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM438741(N-{1-[(4S)-7-(3,5-dimethylisoxazol-4-yl)- 4-pyridi...)
Affinity DataIC50: 25nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM362654(US9834565, Example 9 | (4S)-7-(3,5-dimethylisoxazo...)
Affinity DataIC50: 25nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM438742(N-{1-[(4S)-7-(3,5-dimethylisoxazol-4-yl)- 4-pyridi...)
Affinity DataIC50: 25nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM362642(US9834565, Example 4 | (4S)-2-(5-acetyl-2,5- diaza...)
Affinity DataIC50: 25nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM438739(N-{1-[(4S)-7-(3,5-dimethylisoxazol-4-yl)- 4-pyridi...)
Affinity DataIC50: 25nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM362565((4S)-2-[(2S)-4-acetyl-2-methylpiperazin-1- yl]-7-(...)
Affinity DataIC50: 25nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM438740(N-{1-[(4S)-7-(3,5-dimethylisoxazol-4-yl)- 4-pyridi...)
Affinity DataIC50: 25nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM362651(US9834565, Example 6 | N-{1-[(4S)-7-(3,5-dimethyli...)
Affinity DataIC50: 25nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM438737(N-{1-[(4S)-7-(3,5-dimethylisoxazol-4-yl)- 4-pyridi...)
Affinity DataIC50: 25nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM362650(US9834565, Example 5 | N-{1-[(4S)-7-(3,5-dimethyli...)
Affinity DataIC50: 25nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM438738(N-{1-[(4S)-7-(3,5-dimethylisoxazol-4-yl)- 4-pyridi...)
Affinity DataIC50: 25nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM362661(US9834565, Example 16 | N-{1-[(4S)-7-(3,5-dimethyl...)
Affinity DataIC50: 25nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM362428((4S)-7-(3,5-Dimethylisoxazol-4-yl)-2-(4-isobutyryl...)
Affinity DataIC50: 25nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM362660(US9834565, Example 15 | N-{1-[(4S)-7-(3,5-dimethyl...)
Affinity DataIC50: 25nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM362663(US9834565, Example 18 | N-{1-[(4S)-7-(3,5-dimethyl...)
Affinity DataIC50: 25nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM362673(US9834565, Example 28 | (4S)-2-[4-(cyclobutylcarbo...)
Affinity DataIC50: 25nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM362565((4S)-2-[(2S)-4-acetyl-2-methylpiperazin-1- yl]-7-(...)
Affinity DataIC50: 25nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM362662(US9834565, Example 17 | N-{1-[(4S)-7-(3,5-dimethyl...)
Affinity DataIC50: 25nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM362674(US9834565, Example 29 | (4S)-7-(3,5-dimethylisoxaz...)
Affinity DataIC50: 25nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM362504((4S)-2-[(2R,6S)-4-Acetyl-2,6-dimethylpiperazin-1-y...)
Affinity DataIC50: 25nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM362657(US9834565, Example 12 | N-{1-[(4S)-7-(3,5-dimethyl...)
Affinity DataIC50: 25nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM362671(US9834565, Example 26 | (4S)-7-(3,5-dimethylisoxaz...)
Affinity DataIC50: 25nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM362656(US9834565, Example 11 | N-{1-[(4S)-7-(3,5-dimethyl...)
Affinity DataIC50: 25nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details
Go to US Patent

Displayed 1 to 50 (of 1490 total ) | Next | Last >>
Jump to: