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Report error Found 40 Enz. Inhib. hit(s) with Target = 'Bromodomain and PHD finger-containing protein 3'
TargetBromodomain and PHD finger-containing protein 3(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50504160(CHEMBL3133807 | US11773085, Compound B25)
Affinity DataKd:  8.62E+3nMAssay Description:Reverse ITC (compound as receptor). Domain start/stop: L591-P711More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
PubMed
TargetBromodomain and PHD finger-containing protein 3(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50366670(CHEMBL4173488)
Affinity DataKd: >5.00E+3nMAssay Description:Binding affinity to human BRPF3 (E588 to G701 residues) expressed in bacterial expression system by BROMOScan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetBromodomain and PHD finger-containing protein 3(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50455480(CHEMBL4218735)
Affinity DataKd: <3.02E+4nMAssay Description:Binding affinity to human partial length DNA-tagged BRPF3 expressed in bacteria by BROMOscan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain and PHD finger-containing protein 3(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50249810(CHEMBL4102050)
Affinity DataKd:  940nMAssay Description:Binding affinity to human BRPF3 by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2020
Entry Details Article
PubMed
TargetBromodomain and PHD finger-containing protein 3(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM179481(US9675697, Cpd. No. 73)
Affinity DataKd: >4.00E+3nMAssay Description:Binding affinity to human partial length BRPF3 (E588 to G701 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain and PHD finger-containing protein 3(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50453949(CHEMBL4208820 | US11247989, Example 87)
Affinity DataKd:  5.40E+3nMAssay Description:Binding affinity to human partial length BRPF3 (E588 to G701 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain and PHD finger-containing protein 3(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM249277(US9458145, 1020-18 | US10017501, Compound 1020-18)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to human partial length BRPF3 (E588 to G701 residues) expressed in bacterial expression system after 1 hr by bromoscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetBromodomain and PHD finger-containing protein 3(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50514857(CHEMBL4449894)
Affinity DataKd:  126nMAssay Description:Binding affinity to human partial length BRPF3 (E588 to G701 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetBromodomain and PHD finger-containing protein 3(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50539801(CHEMBL4648912 | US11840533, Compound 70)
Affinity DataKd: <1nMAssay Description:Binding affinity to human partial length BRPF3 (E588 to G701 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetBromodomain and PHD finger-containing protein 3(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM220447(US9296741, 36 | US10633379, Compound X)
Affinity DataKd: >1.00E+3nMAssay Description:Binding affinity to human BRPF3 (E588 to G701 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2019
Entry Details Article
PubMed
TargetBromodomain and PHD finger-containing protein 3(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50631966(CHEMBL5394573)
Affinity DataKd:  1.00E+4nMAssay Description:Binding affinity to BRPF3 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetBromodomain and PHD finger-containing protein 3(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50157570(NI-57 | D0O6XT | NI 57 | GTPL8573 | 4-cyano-N-(1,3...)
Affinity DataKd:  410nMAssay Description:Binding affinity to BRPF3 (unknown origin) by isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetBromodomain and PHD finger-containing protein 3(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50148549(OF-1 | OF 1 | 4-Bromo-N-(2,3-dihydro-6-methoxy-1,3...)
Affinity DataKd:  2.40E+3nMAssay Description:Binding affinity to BRPF3 (unknown origin) by isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetBromodomain and PHD finger-containing protein 3(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50150818(CHEMBL3774575)
Affinity DataKd:  27nMAssay Description:Binding affinity to recombinant human BRPF3 expressed in bacterial system by bromoscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2017
Entry Details Article
PubMed
TargetBromodomain and PHD finger-containing protein 3(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50615275(CHEMBL5282240)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to human partial length BRPF3 (E588 to G701 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetBromodomain and PHD finger-containing protein 3(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM321437((E)-6-(but-2-en-1-yl)-4-(4-(2-hydroxypropan-2-yl)-...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to human partial length BRPF3 (E588 to G701 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetBromodomain and PHD finger-containing protein 3(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50615276(CHEMBL5270178)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to human partial length BRPF3 (E588 to G701 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetBromodomain and PHD finger-containing protein 3(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM321424(6-[(E)-but-2-enyl]-4-[2,5-dimethoxy-4-(morpholine-...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to human partial length BRPF3 (E588 to G701 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetBromodomain and PHD finger-containing protein 3(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50028142(CHEMBL2177300)
Affinity DataIC50: 1nMAssay Description:Inhibition of human BRPF3 by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetBromodomain and PHD finger-containing protein 3(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50249810(CHEMBL4102050)
Affinity DataIC50: 260nMAssay Description:Inhibition of human BRPF3 expressed in Escherichia coli BL21 after 1 hr by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2020
Entry Details Article
PubMed
TargetBromodomain and PHD finger-containing protein 3(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50249770(CHEMBL4076056)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human BRPF3 expressed in Escherichia coli BL21 after 1 hr by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2020
Entry Details Article
PubMed
TargetBromodomain and PHD finger-containing protein 3(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50603594(CHEMBL5205457)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of His-tagged recombinant BRPF3 (unknown origin) (11 to 188 residues) using SGRGK(Ac)GGK(Ac)GLGK(Ac)GGAK(Ac)RHRK(Biotin)-OH as substrate m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetBromodomain and PHD finger-containing protein 3(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50157570(NI-57 | D0O6XT | NI 57 | GTPL8573 | 4-cyano-N-(1,3...)
Affinity DataIC50: 1.01E+3nMpH: 7.4 T: 2°CAssay Description:Assays were performed as described previously with minor modifications(Philpott et al., 2011). All reagents were diluted in 25 mM HEPES, 100 mM NaCl,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details Article
PubMed
TargetBromodomain and PHD finger-containing protein 3(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50157570(NI-57 | D0O6XT | NI 57 | GTPL8573 | 4-cyano-N-(1,3...)
Affinity DataIC50: 1.01E+3nMAssay Description:Alphascreen assay. Binding to BRPF3A (domain start/stop: L591-P711) by alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetBromodomain and PHD finger-containing protein 3(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50249810(CHEMBL4102050)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human His tagged BRPF3 incubated for 30 mins followed by addition of biotinylated peptide and further incubation for 30 mins measured b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2020
Entry Details Article
PubMed
TargetBromodomain and PHD finger-containing protein 3(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50267003(CHEMBL4081438)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human BRPF3 expressed in Escherichia coli BL21 after 1 hr by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2020
Entry Details Article
PubMed
TargetBromodomain and PHD finger-containing protein 3(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50148478(CHEMBL3769965 | US10702504, Compound A)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of BRPF3 (unknown origin) by Alpha Screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2017
Entry Details Article
PubMed
TargetBromodomain and PHD finger-containing protein 3(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50249772(CHEMBL4067436)
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of human BRPF3 expressed in Escherichia coli BL21 after 1 hr by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2020
Entry Details Article
PubMed
TargetBromodomain and PHD finger-containing protein 3(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50267004(CHEMBL4096095)
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of human BRPF3 expressed in Escherichia coli BL21 after 1 hr by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2020
Entry Details Article
PubMed
TargetBromodomain and PHD finger-containing protein 3(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM342597(N-[3-(3-methyl-4-oxo-4,5,6,7-tetrahydro-2H-isoindo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human BRPF3 (E588 to G701 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2019
Entry Details Article
PubMed
TargetBromodomain and PHD finger-containing protein 3(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50504159(CHEMBL4583297)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of BRPF3 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetBromodomain and PHD finger-containing protein 3(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50256397(CHEMBL4088466)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human BRPF3 (E588 to G701 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2019
Entry Details Article
PubMed
TargetBromodomain and PHD finger-containing protein 3(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50158624(CHEMBL3786012)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human BRPF3 (E588 to G701 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2019
Entry Details Article
PubMed
TargetBromodomain and PHD finger-containing protein 3(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50267008(CHEMBL4078047)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human BRPF3 expressed in Escherichia coli BL21 after 1 hr by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2020
Entry Details Article
PubMed
TargetBromodomain and PHD finger-containing protein 3(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50558065(CHEMBL4780530)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of BRPF3 (unknown origin) measured after 70 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetBromodomain and PHD finger-containing protein 3(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50189403(CHEMBL3828191)
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of synthetic fluorescent ligand binding to recombinant truncated 6HisFlag-Tev-BRPF3 (579 to 706 residues) (unknown origin) expressed in Es...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2017
Entry Details Article
PubMed
TargetBromodomain and PHD finger-containing protein 3(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50249797(CHEMBL4059509)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human BRPF3 expressed in Escherichia coli BL21 after 1 hr by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2020
Entry Details Article
PubMed
TargetBromodomain and PHD finger-containing protein 3(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50032912(CHEMBL1522313)
Affinity DataIC50: 1.00E+5nMAssay Description:Binding affinity to 6H-Flag-tagged Tev-BRPF3 (579-706 aa) (unknown origin) by TR-FRET competitive assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetBromodomain and PHD finger-containing protein 3(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50234923(CHEMBL4069412)
Affinity DataKi:  100nMAssay Description:Binding affinity to human partial length BRPF3 expressed in bacterial expression system by BROMOscan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2019
Entry Details Article
PubMed
TargetBromodomain and PHD finger-containing protein 3(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50098311(CHEMBL3590408)
Affinity DataKi:  794nMAssay Description:Binding affinity to BRPF3 (unknown origin) by BROMOscan panel based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed