Compile Data Set for Download or QSAR
Report error Found 122 Enz. Inhib. hit(s) with Target = 'Bromodomain adjacent to zinc finger domain protein 2B'
TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50092310(US9675697, Cpd. No. 23 | CHEMBL3581661)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to biotinylated BAZ2B (2054 to 2168 amino acid residues) (unknown origin) expressed in Rosetta2 DE3 cells by bio-layer interferometr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2016
Entry Details Article
PubMed
TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50098250(CHEMBL3590389)
Affinity DataKd: <1.00E+5nMAssay Description:Binding affinity to BAZ2B in human HUT78 cells incubated for 45 mins by mass spectrometry based bromosphere chemoproteomic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50098305(CHEMBL3590405)
Affinity DataKd:  7.94E+3nMAssay Description:Binding affinity to BAZ2B in human HUT78 cells incubated for 45 mins by mass spectrometry based bromosphere chemoproteomic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50098311(CHEMBL3590408)
Affinity DataKd: <1.00E+5nMAssay Description:Binding affinity to BAZ2B in human HUT78 cells incubated for 45 mins by mass spectrometry based bromosphere chemoproteomic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50148270(CHEMBL3739699)
Affinity DataKd:  60nMAssay Description:Binding affinity to recombinant His6-TEV fused human BAZ2B expressed in Escherichia coli by isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2017
Entry Details Article
PubMed
TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50150818(CHEMBL3774575)
Affinity DataKd:  400nMAssay Description:Binding affinity to recombinant human BAZ2B expressed in bacterial system by bromoscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2017
Entry Details Article
PubMed
TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM71168(2-chloranyl-N-(1-ethanoylindol-3-yl)-N-phenyl-etha...)
Affinity DataKd: >5.00E+4nMAssay Description:Competitive binding affinity to human His-tagged BRAZ2B (1858 to 1972 residues) expressed in T7 phage-infected Escherichia coli BL21(DE3) cells measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details Article
PubMed
TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50172114(CHEMBL3808440)
Affinity DataKd:  1.40E+5nMAssay Description:Competitive binding affinity to human His-tagged BRAZ2B (1858 to 1972 residues) expressed in T7 phage-infected Escherichia coli BL21(DE3) cells measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details Article
PubMed
TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50172115(CHEMBL3810055)
Affinity DataKd:  2.30E+4nMAssay Description:Competitive binding affinity to human His-tagged BRAZ2B (1858 to 1972 residues) expressed in T7 phage-infected Escherichia coli BL21(DE3) cells measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50172116(CHEMBL3809983)
Affinity DataKd:  3.90E+4nMAssay Description:Competitive binding affinity to human His-tagged BRAZ2B (1858 to 1972 residues) expressed in T7 phage-infected Escherichia coli BL21(DE3) cells measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM220447(US9296741, 36 | US10633379, Compound X)
Affinity DataKd: >1.00E+3nMAssay Description:Binding affinity to human BAZ2B (S2054 to S2168 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2019
Entry Details Article
PubMed
TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50366670(CHEMBL4173488)
Affinity DataKd: >5.00E+3nMAssay Description:Binding affinity to human BAZ2B (S2054 to S2168 residues) expressed in bacterial expression system by BROMOScan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50455480(CHEMBL4218735)
Affinity DataKd: <3.02E+4nMAssay Description:Binding affinity to human partial length DNA-tagged BAZ2B expressed in bacterial by BROMOscan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50277359(CHEMBL1612460)
Affinity DataKd: >5.00E+5nMAssay Description:Binding affinity to human BAZ2B (S2054 to S2168 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details Article
PubMed
TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50277366(CHEMBL4171398)
Affinity DataKd:  5.40E+4nMAssay Description:Binding affinity to human BAZ2B (S2054 to S2168 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50277360(CHEMBL4166955)
Affinity DataKd:  8.70E+4nMAssay Description:Binding affinity to human BAZ2B (S2054 to S2168 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50277367(CHEMBL4163507)
Affinity DataKd: >5.00E+5nMAssay Description:Binding affinity to human BAZ2B (S2054 to S2168 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM179481(US9675697, Cpd. No. 73)
Affinity DataKd: >4.00E+3nMAssay Description:Binding affinity to human partial length BAZ2B (S2054 to S2168 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50453949(CHEMBL4208820 | US11247989, Example 87)
Affinity DataKd:  1.90E+3nMAssay Description:Binding affinity to human partial length BAZ2B (S2054 to S2168 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50468912(CHEMBL4284812)
Affinity DataKd:  6.00E+3nMAssay Description:Binding affinity to recombinant human BAZ2B (S2054 to S2168 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50495361(CHEMBL3110228)
Affinity DataKd:  1.00E+4nMAssay Description:Binding affinity to human BAZ2B expressed in Escherichia coli BL21(DE3) by competitive isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50495363(CHEMBL3110239)
Affinity DataKd: >1.00E+5nMAssay Description:Binding affinity to human BAZ2B expressed in Escherichia coli BL21(DE3) by direct isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50495365(CHEMBL3110241)
Affinity DataKd:  8.00E+3nMAssay Description:Binding affinity to human BAZ2B expressed in Escherichia coli BL21(DE3) by direct isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50495368(CHEMBL3110242)
Affinity DataKd:  1.70E+4nMAssay Description:Binding affinity to human BAZ2B expressed in Escherichia coli BL21(DE3) by direct isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50495369(CHEMBL3110260)
Affinity DataKd:  6.94E+5nMAssay Description:Binding affinity to human BAZ2B expressed in Escherichia coli BL21(DE3) by competitive isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50495370(CHEMBL3110254)
Affinity DataKd:  3.36E+5nMAssay Description:Binding affinity to human BAZ2B expressed in Escherichia coli BL21(DE3) by competitive isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50495371(CHEMBL3110247)
Affinity DataKd:  6.50E+4nMAssay Description:Binding affinity to human BAZ2B expressed in Escherichia coli BL21(DE3) by competitive isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50495380(CHEMBL2441350)
Affinity DataKd:  5.24E+5nMAssay Description:Binding affinity to human BAZ2B expressed in Escherichia coli BL21(DE3) by direct isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50495383(CHEMBL3110255)
Affinity DataKd:  2.74E+5nMAssay Description:Binding affinity to human BAZ2B expressed in Escherichia coli BL21(DE3) by competitive isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM249277(US9458145, 1020-18 | US10017501, Compound 1020-18)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to human partial length BAZ2B (S2054 to S2168 residues) expressed in bacterial expression system after 1 hr by bromoscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50539801(CHEMBL4648912 | US11840533, Compound 70)
Affinity DataKd: <1nMAssay Description:Binding affinity to human partial length BAZ2B (S2054 to S2168 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50615275(CHEMBL5282240)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to human partial length BAZ2B (S2054 to S2168 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM321437((E)-6-(but-2-en-1-yl)-4-(4-(2-hydroxypropan-2-yl)-...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to human partial length BAZ2B (S2054 to S2168 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50615276(CHEMBL5270178)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to human partial length BAZ2B (S2054 to S2168 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM321424(6-[(E)-but-2-enyl]-4-[2,5-dimethoxy-4-(morpholine-...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to human partial length BAZ2B (S2054 to S2168 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50148270(CHEMBL3739699)
Affinity DataKd:  100nMAssay Description:Inhibition of recombinant His6-TEV fused human BAZ2B expressed in Escherichia coli incubated for 30 mins in presence of biotinylated peptide by alpha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2017
Entry Details Article
PubMed
TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50183448(CHEMBL3823478 | US11773085, Compound B2)
Affinity DataKd:  1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50078630(CHEMBL4296718)
Affinity DataIC50: 174nMAssay Description:Displacement of H3K14Ac from BAZ2B (unknown origin) preincubated for 30 mins with non-biotinylated peptide followed by addition of biotinylated pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50148270(CHEMBL3739699)
Affinity DataIC50: 360nMAssay Description:Competitive binding affinity to His-tagged BRAZ2B (unknown origin) expressed in Escherichia coli BL21(DE3) cells by AlphaScreen assay in presence of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details Article
PubMed
TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50148282(CHEMBL3771216)
Affinity DataIC50: 370nMAssay Description:Inhibition of recombinant His6-TEV fused human BAZ2B expressed in Escherichia coli incubated for 30 mins in presence of biotinylated peptide by alpha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2017
Entry Details Article
PubMed
TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50148283(CHEMBL3770155)
Affinity DataIC50: 410nMAssay Description:Inhibition of recombinant His6-TEV fused human BAZ2B expressed in Escherichia coli incubated for 30 mins in presence of biotinylated peptide by alpha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2017
Entry Details Article
PubMed
TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50148270(CHEMBL3739699)
Affinity DataIC50: 430nMAssay Description:Binding affinity to biotinylated C-terminal Avi/His-TEV-tagged BAZ2B (unknown origin) expressed in Escherichia coli by Biolayer Interferometric analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2017
Entry Details Article
PubMed
TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50148284(CHEMBL3770449)
Affinity DataIC50: 540nMAssay Description:Inhibition of recombinant His6-TEV fused human BAZ2B expressed in Escherichia coli incubated for 30 mins in presence of biotinylated peptide by alpha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2017
Entry Details Article
PubMed
TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50148288(CHEMBL3770493)
Affinity DataIC50: 610nMAssay Description:Inhibition of recombinant His6-TEV fused human BAZ2B expressed in Escherichia coli incubated for 30 mins in presence of biotinylated peptide by alpha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2017
Entry Details Article
PubMed
TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50148289(CHEMBL3770199)
Affinity DataIC50: 670nMAssay Description:Inhibition of recombinant His6-TEV fused human BAZ2B expressed in Escherichia coli incubated for 30 mins in presence of biotinylated peptide by alpha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2017
Entry Details Article
PubMed
TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50148334(CHEMBL3770214)
Affinity DataIC50: 820nMAssay Description:Inhibition of recombinant His6-TEV fused human BAZ2B expressed in Escherichia coli incubated for 30 mins in presence of biotinylated peptide by alpha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2017
Entry Details Article
PubMed
TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50148290(CHEMBL3770277)
Affinity DataIC50: 840nMAssay Description:Inhibition of recombinant His6-TEV fused human BAZ2B expressed in Escherichia coli incubated for 30 mins in presence of biotinylated peptide by alpha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2017
Entry Details Article
PubMed
TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50148276(CHEMBL3770112)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant His6-TEV fused human BAZ2B expressed in Escherichia coli incubated for 30 mins in presence of biotinylated peptide by alpha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2017
Entry Details Article
PubMed
TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM342597(N-[3-(3-methyl-4-oxo-4,5,6,7-tetrahydro-2H-isoindo...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human BAZ2B (S2054 to S2168 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2019
Entry Details Article
PubMed
TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50158624(CHEMBL3786012)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human BAZ2B (S2054 to S2168 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2019
Entry Details Article
PubMed
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