Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with Target = 'Beta-secretase 1 [22-457]'
TargetBeta-secretase 1 [22-457](Human)
Philipps University Marburg

LigandPNGBDBM32384(phenyl-substituted sulfonamides, 6a)
Affinity DataIC50: 2.50E+5nMT: 2°CAssay Description:Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMed
TargetBeta-secretase 1 [22-457](Human)
Philipps University Marburg

LigandPNGBDBM32385(phenyl-substituted sulfonamides, 6b)
Affinity DataIC50: 2.50E+5nMT: 2°CAssay Description:Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMed
TargetBeta-secretase 1 [22-457](Human)
Philipps University Marburg

LigandPNGBDBM32387(phenyl-substituted sulfonamides, 6d)
Affinity DataIC50: 2.50E+5nMT: 2°CAssay Description:Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMed
TargetBeta-secretase 1 [22-457](Human)
Philipps University Marburg

LigandPNGBDBM32388(phenyl-substituted sulfonamides, 6e)
Affinity DataIC50: 2.50E+5nMT: 2°CAssay Description:Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMed
TargetBeta-secretase 1 [22-457](Human)
Philipps University Marburg

LigandPNGBDBM32390(iso-butyl-substituted sulfonamide, 9a)
Affinity DataIC50: 2.50E+5nMT: 2°CAssay Description:Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMed
TargetBeta-secretase 1 [22-457](Human)
Philipps University Marburg

LigandPNGBDBM32391(iso-butyl-substituted sulfonamide, 9b)
Affinity DataIC50: 2.50E+5nMT: 2°CAssay Description:Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMed
TargetBeta-secretase 1 [22-457](Human)
Philipps University Marburg

LigandPNGBDBM32392(carboxamide, 12a)
Affinity DataIC50: 2.50E+5nMT: 2°CAssay Description:Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMed
TargetBeta-secretase 1 [22-457](Human)
Philipps University Marburg

LigandPNGBDBM32393(carboxamide, 12b)
Affinity DataIC50: 2.50E+5nMT: 2°CAssay Description:Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMed
TargetBeta-secretase 1 [22-457](Human)
Philipps University Marburg

LigandPNGBDBM32394(carboxamide, 12c)
Affinity DataIC50: 2.50E+5nMT: 2°CAssay Description:Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMed
TargetBeta-secretase 1 [22-457](Human)
Philipps University Marburg

LigandPNGBDBM32389(phenyl-substituted sulfonamides, 6f)
Affinity DataKi:  6.40E+4nM ΔG°:  -23.9kJ/moleT: 2°CAssay Description:Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMed
TargetBeta-secretase 1 [22-457](Human)
Philipps University Marburg

LigandPNGBDBM32386(phenyl-substituted sulfonamides, 6c)
Affinity DataKi:  1.50E+5nM ΔG°:  -21.8kJ/moleT: 2°CAssay Description:Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMed