Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with Target = 'Beta-adrenergic receptor kinase 2'
TargetBeta-adrenergic receptor kinase 2(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM525308(US11173144, Compound 72)
Affinity DataIC50: 0.00900nMAssay Description:ADRB2 IC50 from binding assay(nM), Determined using the Tag-lite Adrenoceptor Beta2 receptor ligand binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
Go to US Patent

TargetBeta-adrenergic receptor kinase 2(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM525317(US11173144, Compound 90)
Affinity DataIC50: 0.0190nMAssay Description:ADRB2 IC50 from binding assay(nM), Determined using the Tag-lite Adrenoceptor Beta2 receptor ligand binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
Go to US Patent

TargetBeta-adrenergic receptor kinase 2(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM525320(US11173144, Compound 52)
Affinity DataIC50: 0.0240nMAssay Description:ADRB2 IC50 from binding assay(nM), Determined using the Tag-lite Adrenoceptor Beta2 receptor ligand binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
Go to US Patent

TargetBeta-adrenergic receptor kinase 2(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM525316(US11173144, Compound 69)
Affinity DataIC50: 0.0480nMAssay Description:ADRB2 IC50 from binding assay(nM), Determined using the Tag-lite Adrenoceptor Beta2 receptor ligand binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
Go to US Patent

TargetBeta-adrenergic receptor kinase 2(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM525318(US11173144, Compound 75)
Affinity DataIC50: 0.0650nMAssay Description:ADRB2 IC50 from binding assay(nM), Determined using the Tag-lite Adrenoceptor Beta2 receptor ligand binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
Go to US Patent

TargetBeta-adrenergic receptor kinase 2(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM525322(US11173144, Compound 86)
Affinity DataIC50: 0.144nMAssay Description:ADRB2 IC50 from binding assay(nM), Determined using the Tag-lite Adrenoceptor Beta2 receptor ligand binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
Go to US Patent

TargetBeta-adrenergic receptor kinase 2(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM525319(US11173144, Compound 87)
Affinity DataIC50: 0.230nMAssay Description:ADRB2 IC50 from binding assay(nM), Determined using the Tag-lite Adrenoceptor Beta2 receptor ligand binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
Go to US Patent

TargetBeta-adrenergic receptor kinase 2(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM525321(US11173144, Compound 55)
Affinity DataIC50: 0.380nMAssay Description:ADRB2 IC50 from binding assay(nM), Determined using the Tag-lite Adrenoceptor Beta2 receptor ligand binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
Go to US Patent

TargetBeta-adrenergic receptor kinase 2(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM50257340(CHEMBL4072828)
Affinity DataIC50: 0.650nMAssay Description:Inhibition of recombinant human full length GST-tagged GRK3 expressed in baculovirus using ulight topo2alpha as substrate preincubated for 60 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2019
Entry Details Article
PubMed
TargetBeta-adrenergic receptor kinase 2(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM50257328(CHEMBL4082775)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of recombinant human full length GST-tagged GRK3 expressed in baculovirus using ulight topo2alpha as substrate preincubated for 60 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2019
Entry Details Article
PubMed
TargetBeta-adrenergic receptor kinase 2(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM50257365(CHEMBL4083276)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of recombinant human full length GST-tagged GRK3 expressed in baculovirus using ulight topo2alpha as substrate preincubated for 60 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2019
Entry Details Article
PubMed
TargetBeta-adrenergic receptor kinase 2(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM50257344(CHEMBL4065690)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of recombinant human full length GST-tagged GRK3 expressed in baculovirus using ulight topo2alpha as substrate preincubated for 60 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2019
Entry Details Article
PubMed
TargetBeta-adrenergic receptor kinase 2(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM50257350(CHEMBL1738877)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of recombinant human full length GST-tagged GRK3 expressed in baculovirus using ulight topo2alpha as substrate preincubated for 60 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBeta-adrenergic receptor kinase 2(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM50257350(CHEMBL1738877)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of GRK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetBeta-adrenergic receptor kinase 2(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM50257351(CHEMBL4095595)
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant human full length GST-tagged GRK3 expressed in baculovirus using ulight topo2alpha as substrate preincubated for 60 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2019
Entry Details Article
PubMed
TargetBeta-adrenergic receptor kinase 2(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM3149(Acyclic Balanol Analog (-)-1 | 2-{[2,6-dihydroxy-4...)
Affinity DataIC50: 47nMAssay Description:Inhibition of GRK3-mediated bovine tubulin phosphorylation by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetBeta-adrenergic receptor kinase 2(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 850nMAssay Description:Inhibition of human GRK3 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetBeta-adrenergic receptor kinase 2(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 861nMAssay Description:Inhibition of human GRK3 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetBeta-adrenergic receptor kinase 2(Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50191311(CHEMBL3950887)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of recombinant bovine GRK3 expressed in Sf9 insect cells assessed as decrease in phosphorylation of urea-washed bovine rod outer segments ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2018
Entry Details Article
PubMed
TargetBeta-adrenergic receptor kinase 2(Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50191313(CHEMBL3931500)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of recombinant bovine GRK3 expressed in Sf9 insect cells assessed as decrease in phosphorylation of urea-washed bovine rod outer segments ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2018
Entry Details Article
PubMed
TargetBeta-adrenergic receptor kinase 2(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM50566949(CHEMBL4877302)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human GRK3 using casein as substrate in presence of [gamma33P]ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetBeta-adrenergic receptor kinase 2(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM50566947(CHEMBL4847703)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human GRK3 using casein as substrate in presence of [gamma33P]ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetBeta-adrenergic receptor kinase 2(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM50566946(CHEMBL4854871)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human GRK3 using casein as substrate in presence of [gamma33P]ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetBeta-adrenergic receptor kinase 2(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM50519662(CHEMBL4438748)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant full length human GRK3 using casein as substrate after 40 mins in presence of [gamma-33ATP] by radiometric scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetBeta-adrenergic receptor kinase 2(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM50135286(CHEMBL3745885)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human GRK3 using casein as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2017
Entry Details Article
PubMed
TargetBeta-adrenergic receptor kinase 2(Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50191319(CHEMBL3942164)
Affinity DataIC50: 1.16E+4nMAssay Description:Inhibition of recombinant bovine GRK3 expressed in Sf9 insect cells assessed as decrease in phosphorylation of urea-washed bovine rod outer segments ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2018
Entry Details Article
PubMed
TargetBeta-adrenergic receptor kinase 2(Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50191326(CHEMBL3953837)
Affinity DataIC50: 2.26E+4nMAssay Description:Inhibition of recombinant bovine GRK3 expressed in Sf9 insect cells assessed as decrease in phosphorylation of urea-washed bovine rod outer segments ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2018
Entry Details Article
PubMed
TargetBeta-adrenergic receptor kinase 2(Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50191312(CHEMBL3900757)
Affinity DataIC50: 3.04E+4nMAssay Description:Inhibition of recombinant bovine GRK3 expressed in Sf9 insect cells assessed as decrease in phosphorylation of urea-washed bovine rod outer segments ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2018
Entry Details Article
PubMed
TargetBeta-adrenergic receptor kinase 2(Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50191310(CHEMBL3971763)
Affinity DataIC50: 5.55E+4nMAssay Description:Inhibition of recombinant bovine GRK3 expressed in Sf9 insect cells assessed as decrease in phosphorylation of urea-washed bovine rod outer segments ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2018
Entry Details Article
PubMed
TargetBeta-adrenergic receptor kinase 2(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant full length human GST-tagged GRK3 expressed in baculovirus expression system using serine/threonine-16 peptide as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed