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Report error Found 2040 Enz. Inhib. hit(s) with Target = 'Aminopeptidase N'
TargetAminopeptidase N(Pig)
Montana State University

LigandPNGBDBM23698(4-chloro-1-[(4-fluorophenyl)carbonyl]-1H-pyrazole ...)
Affinity DataAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Montana State University

LigandPNGBDBM23700(methyl 1-[(4-chlorophenyl)carbonyl]-1H-pyrazole-5-...)
Affinity DataAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Montana State University

LigandPNGBDBM23701(4-chloro-1-[(3-nitrophenyl)carbonyl]-1H-pyrazole |...)
Affinity DataAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Montana State University

LigandPNGBDBM23702(3-[(2,4-dimethylphenyl)carbonyl]-1-[(4-fluoropheny...)
Affinity DataAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Montana State University

LigandPNGBDBM23703(1-benzoyl-4-nitro-1H-pyrazole | N-Benzoylpyrazole ...)
Affinity DataAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Montana State University

LigandPNGBDBM23704(1-benzoyl-N-phenyl-1H-pyrazole-3-carboxamide | N-B...)
Affinity DataAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Montana State University

LigandPNGBDBM23705(4-bromo-1-[(4-methylphenyl)carbonyl]-1H-pyrazole |...)
Affinity DataAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Montana State University

LigandPNGBDBM23706(1-[(3,4-dichlorophenyl)carbonyl]-1H-pyrazole | N-B...)
Affinity DataAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Montana State University

LigandPNGBDBM23707(1-[(2-fluorophenyl)carbonyl]-5-methyl-3-nitro-1H-p...)
Affinity DataAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Montana State University

LigandPNGBDBM23708(4-bromo-1-[(2,6-difluorophenyl)carbonyl]-1H-pyrazo...)
Affinity DataAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Montana State University

LigandPNGBDBM23709(3-methyl-1-[(3,4,5-trimethoxyphenyl)carbonyl]-1H-p...)
Affinity DataAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Montana State University

LigandPNGBDBM23710(1-[(4-methylphenyl)carbonyl]-3-nitro-1H-pyrazole |...)
Affinity DataAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Montana State University

LigandPNGBDBM23711(1-benzoyl-3-nitro-1H-pyrazole | N-Benzoylpyrazole ...)
Affinity DataAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Montana State University

LigandPNGBDBM23712(1-[(2-methylphenyl)carbonyl]-4-nitro-1H-pyrazole |...)
Affinity DataAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Montana State University

LigandPNGBDBM23713(4-chloro-1-[(2-methylphenyl)carbonyl]-1H-pyrazole ...)
Affinity DataAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Montana State University

LigandPNGBDBM23714(4-bromo-1-[(3-methylphenyl)carbonyl]-1H-pyrazole |...)
Affinity DataAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Montana State University

LigandPNGBDBM23715(4-bromo-1-[(2-methylphenyl)carbonyl]-1H-pyrazole |...)
Affinity DataAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Montana State University

LigandPNGBDBM23716(N-{4-[(3-methyl-1H-pyrazol-1-yl)carbonyl]phenyl}ac...)
Affinity DataAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Montana State University

LigandPNGBDBM23717(4-chloro-1-[(2-chlorophenyl)carbonyl]-1H-pyrazole ...)
Affinity DataAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Montana State University

LigandPNGBDBM23718(1-[(2-methylphenyl)carbonyl]-1H-pyrazole | N-Benzo...)
Affinity DataAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Montana State University

LigandPNGBDBM23719(4-bromo-1-[(2-chloro-4,5-difluorophenyl)carbonyl]-...)
Affinity DataAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Montana State University

LigandPNGBDBM23720(1-[(4-tert-butylphenyl)carbonyl]-4-chloro-1H-pyraz...)
Affinity DataAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Montana State University

LigandPNGBDBM23721(4-chloro-1-[(2-fluorophenyl)carbonyl]-3,5-dimethyl...)
Affinity DataAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Montana State University

LigandPNGBDBM23722(4-chloro-1-[(4-chlorophenyl)carbonyl]-3,5-dimethyl...)
Affinity DataAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Montana State University

LigandPNGBDBM23723(cid_714833 | 4-bromo-1-[(4-methoxyphenyl)carbonyl]...)
Affinity DataAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Montana State University

LigandPNGBDBM23724(1-[(2-bromophenyl)carbonyl]-1H-pyrazole | N-Benzoy...)
Affinity DataAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Montana State University

LigandPNGBDBM23725(3,4,5-trimethyl-1-[(3,4,5-trimethoxyphenyl)carbony...)
Affinity DataAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Montana State University

LigandPNGBDBM50002035(CHEMBL17107 | (2-Hydroxycarbamoyl-3-phenyl-propion...)
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against rabbit kidney aminopeptidase using 10 nM of [3H]Leu-enkephalin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetAminopeptidase N(Human)
Sanofi

Curated by ChEMBL
LigandPNGBDBM50076744(CHEMBL3416733)
Affinity DataIC50: 1nMAssay Description:Inhibition of APN (unknown origin) using Ala-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetAminopeptidase N(Human)
Sanofi

Curated by ChEMBL
LigandPNGBDBM50570849(CHEMBL4854733)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of APN (unknown origin) using A-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetAminopeptidase N(Human)
Sanofi

Curated by ChEMBL
LigandPNGBDBM50570849(CHEMBL4854733)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of APN (unknown origin) using A-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Montana State University

LigandPNGBDBM50002022(CHEMBL16779 | (2-Benzyl-3-hydroxycarbamoyl-propion...)
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against rabbit kidney aminopeptidase using 10 nM of [3H]Leu-enkephalin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetAminopeptidase N(Human)
Sanofi

Curated by ChEMBL
LigandPNGBDBM50570850(CHEMBL4877339)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of APN (unknown origin) using A-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetAminopeptidase N(Human)
Sanofi

Curated by ChEMBL
LigandPNGBDBM50570850(CHEMBL4877339)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of APN (unknown origin) using A-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Montana State University

LigandPNGBDBM50025913([2-(Formyl-hydroxy-amino)-3-phenyl-propionylamino]...)
Affinity DataIC50: 2.5nMAssay Description:Inhibitory activity against rabbit kidney aminopeptidase using 10 nM of [3H]Leu-enkephalin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetAminopeptidase N(Human)
Sanofi

Curated by ChEMBL
LigandPNGBDBM50076744(CHEMBL3416733)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of APN (unknown origin) using A-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetAminopeptidase N(Human)
Sanofi

Curated by ChEMBL
LigandPNGBDBM50076744(CHEMBL3416733)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of APN (unknown origin) using A-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Montana State University

LigandPNGBDBM23971(CHEMBL29292 | (2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-...)
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against rabbit kidney aminopeptidase using 10 nM of [3H]Leu-enkephalin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Montana State University

LigandPNGBDBM50020158((RS)-2-(2-Benzyl-3-hydroxycarbamoyl-propionylamino...)
Affinity DataIC50: 7.10nMAssay Description:Inhibitory activity against rabbit kidney aminopeptidase using 10 nM of [3H]Leu-enkephalin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetAminopeptidase N(Human)
Sanofi

Curated by ChEMBL
LigandPNGBDBM50078133(2-Amino-4-methyl-pentane-1-thiol | (S)-2-Amino-4-m...)
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAminopeptidase N(Pig)
Montana State University

LigandPNGBDBM50025915([2-Benzyl-3-(formyl-hydroxy-amino)-propionylamino]...)
Affinity DataIC50: 8.5nMAssay Description:Inhibitory activity against rabbit kidney aminopeptidase using 10 nM of [3H]Leu-enkephalin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetAminopeptidase N(Human)
Sanofi

Curated by ChEMBL
LigandPNGBDBM50570851(CHEMBL4853049)
Affinity DataIC50: 8.60nMAssay Description:Inhibition of APN (unknown origin) using A-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetAminopeptidase N(Human)
Sanofi

Curated by ChEMBL
LigandPNGBDBM50570851(CHEMBL4853049)
Affinity DataIC50: 8.70nMAssay Description:Inhibition of APN (unknown origin) using A-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Montana State University

LigandPNGBDBM50002031(1-Mercaptomethyl-3-methylsulfanyl-propyl-ammonium)
Affinity DataIC50: 11nMAssay Description:Inhibition of [3H]Leu-enkephalin binding to Aminopeptidase N from hog kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetAminopeptidase N(Human)
Sanofi

Curated by ChEMBL
LigandPNGBDBM50457479(CHEMBL1159812)
Affinity DataIC50: 11nMAssay Description:Inhibition of APN (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Montana State University

LigandPNGBDBM50002026(2-Mercapto-1-methylsulfanylmethyl-ethyl-ammonium)
Affinity DataIC50: 20nMAssay Description:Inhibition of [3H]Leu-enkephalin binding to Aminopeptidase N from hog kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Montana State University

LigandPNGBDBM50368599(CHEMBL1159809)
Affinity DataIC50: 20nMAssay Description:Inhibition of [3H]Leu-enkephalin binding to Aminopeptidase N from hog kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Montana State University

LigandPNGBDBM50144944(CHEMBL3764919)
Affinity DataIC50: 20nMAssay Description:Inhibition of APN in porcine kidney microsomes preincubated for 5 mins before L-leu-p-nitroanilide substrate addition for 30 mins by plate reader ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMed
TargetAminopeptidase N(Human)
Sanofi

Curated by ChEMBL
LigandPNGBDBM50457468(CHEMBL4216928)
Affinity DataIC50: 20nMAssay Description:Inhibition of APN (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetAminopeptidase N(Human)
Sanofi

Curated by ChEMBL
LigandPNGBDBM50457471(CHEMBL1159811)
Affinity DataIC50: 20nMAssay Description:Inhibition of APN (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
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