Compile Data Set for Download or QSAR
Report error Found 21588 Enz. Inhib. hit(s) with Target = 'Acetylcholinesterase'
TargetAcetylcholinesterase(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149201(3,8-Diamino-6-phenyl-5-(6-{3-[2-(1,2,3,4-tetrahydr...)
Affinity DataKd:  0.000410nMAssay Description:Dissociation constant towards Acetylcholinesterase in mouseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50204090(CHEMBL3958859)
Affinity DataKi:  0.000590nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2018
Entry Details Article
PubMed
TargetAcetylcholinesterase(Pacific electric ray)
TBA

Curated by ChEMBL
LigandPNGBDBM50281126(1-(3-tert-Butyl-phenyl)-2,2,2-trifluoro-ethanone |...)
Affinity DataKi:  0.00370nMAssay Description:Tested for the ability to inhibit Acetylcholinesterase (AChE) from Torpedo californicaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetAcetylcholinesterase(Human)
Agriibrahim£E£En University

Curated by ChEMBL
LigandPNGBDBM50093582(CHEMBL3585782)
Affinity DataKi:  0.00500nMAssay Description:Inhibition of acetylcholinesterase (unknown origin) assessed as AChI hydrolysis using AChI and DTNB as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Agriibrahim£E£En University

Curated by ChEMBL
LigandPNGBDBM50093588(CHEMBL3585776)
Affinity DataKi:  0.00500nMAssay Description:Inhibition of acetylcholinesterase (unknown origin) assessed as AChI hydrolysis using AChI and DTNB as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Agriibrahim£E£En University

Curated by ChEMBL
LigandPNGBDBM50093587(CHEMBL3585777)
Affinity DataKi:  0.00500nMAssay Description:Inhibition of acetylcholinesterase (unknown origin) assessed as AChI hydrolysis using AChI and DTNB as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Agriibrahim£E£En University

Curated by ChEMBL
LigandPNGBDBM50049862(CHEMBL3322232)
Affinity DataIC50: 0.00600nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Agriibrahim£E£En University

Curated by ChEMBL
LigandPNGBDBM50093581(CHEMBL3585783)
Affinity DataKi:  0.00600nMAssay Description:Inhibition of acetylcholinesterase (unknown origin) assessed as AChI hydrolysis using AChI and DTNB as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Agriibrahim£E£En University

Curated by ChEMBL
LigandPNGBDBM50093589(CHEMBL3585775)
Affinity DataKi:  0.00600nMAssay Description:Inhibition of acetylcholinesterase (unknown origin) assessed as AChI hydrolysis using AChI and DTNB as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Agriibrahim£E£En University

Curated by ChEMBL
LigandPNGBDBM50093583(CHEMBL3585781)
Affinity DataKi:  0.00600nMAssay Description:Inhibition of acetylcholinesterase (unknown origin) assessed as AChI hydrolysis using AChI and DTNB as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Agriibrahim£E£En University

Curated by ChEMBL
LigandPNGBDBM50523376(CHEMBL4589980)
Affinity DataIC50: 0.00800nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Agriibrahim£E£En University

Curated by ChEMBL
LigandPNGBDBM9012(7-[(6,8-dichloro-1,2,3,4-tetrahydroacridin-9-yl)am...)
Affinity DataIC50: 0.00800nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Agriibrahim£E£En University

Curated by ChEMBL
LigandPNGBDBM50093597(CHEMBL3585784)
Affinity DataKi:  0.00800nMAssay Description:Inhibition of acetylcholinesterase (unknown origin) assessed as AChI hydrolysis using AChI and DTNB as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Agriibrahim£E£En University

Curated by ChEMBL
LigandPNGBDBM9012(7-[(6,8-dichloro-1,2,3,4-tetrahydroacridin-9-yl)am...)
Affinity DataIC50: 0.00800nMAssay Description:Inhibition of human AchEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Pacific electric ray)
TBA

Curated by ChEMBL
LigandPNGBDBM50281127(2,2,2-Trifluoro-1-(3-isopropyl-phenyl)-ethanone | ...)
Affinity DataKi:  0.00850nMAssay Description:Tested for the ability to inhibit Acetylcholinesterase (AChE) from Torpedo californicaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetAcetylcholinesterase(Human)
Agriibrahim£E£En University

Curated by ChEMBL
LigandPNGBDBM50093585(CHEMBL3585779)
Affinity DataKi:  0.0110nMAssay Description:Inhibition of acetylcholinesterase (unknown origin) assessed as AChI hydrolysis using AChI and DTNB as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Agriibrahim£E£En University

Curated by ChEMBL
LigandPNGBDBM50456700(CHEMBL4205425)
Affinity DataIC50: 0.0110nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Agriibrahim£E£En University

Curated by ChEMBL
LigandPNGBDBM50271367(N-Methyl-N-(1,2,3,4-tetrahydroacridin-9-yl)-N-{3-[...)
Affinity DataKi:  0.0120nMAssay Description:Inhibition of human acetylcholine esteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2014
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Agriibrahim£E£En University

Curated by ChEMBL
LigandPNGBDBM50271367(N-Methyl-N-(1,2,3,4-tetrahydroacridin-9-yl)-N-{3-[...)
Affinity DataKi:  0.0120nMAssay Description:Inhibition of human recombinant AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Agriibrahim£E£En University

Curated by ChEMBL
LigandPNGBDBM50456689(CHEMBL4205954)
Affinity DataIC50: 0.0130nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Agriibrahim£E£En University

Curated by ChEMBL
LigandPNGBDBM50456692(CHEMBL4209803)
Affinity DataIC50: 0.0140nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Agriibrahim£E£En University

Curated by ChEMBL
LigandPNGBDBM50456691(CHEMBL4210316)
Affinity DataIC50: 0.0140nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Agriibrahim£E£En University

Curated by ChEMBL
LigandPNGBDBM50456690(CHEMBL4217663)
Affinity DataIC50: 0.0140nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Pacific electric ray)
TBA

Curated by ChEMBL
LigandPNGBDBM50271556(N,N,N-trimethyl-3-(2,2,2-trifluoroacetyl)benzenami...)
Affinity DataKi:  0.0150nMAssay Description:Inhibition of Torpedo californica AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Agriibrahim£E£En University

Curated by ChEMBL
LigandPNGBDBM50456693(CHEMBL4214430)
Affinity DataIC50: 0.0170nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Agriibrahim£E£En University

Curated by ChEMBL
LigandPNGBDBM50456699(CHEMBL4213253)
Affinity DataIC50: 0.0190nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Pacific electric ray)
TBA

Curated by ChEMBL
LigandPNGBDBM50304324((1R,9R)-1-{[1-(3,5-Dimethoxy-phenyl)-methylidene]-...)
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of Torpedo california AChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Agriibrahim£E£En University

Curated by ChEMBL
LigandPNGBDBM9022(N-[5-(6-Chloro-1,2,3,4-tetrahydroacridin-9-ylamino...)
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of human AchEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Bovine)
Neuropharma

LigandPNGBDBM9022(N-[5-(6-Chloro-1,2,3,4-tetrahydroacridin-9-ylamino...)
Affinity DataIC50: 0.0200nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Agriibrahim£E£En University

Curated by ChEMBL
LigandPNGBDBM50318731(3-(1H-indol-3-yl)-N-(6-(1,2,3,4-tetrahydroacridin-...)
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Agriibrahim£E£En University

Curated by ChEMBL
LigandPNGBDBM50456696(CHEMBL4214707)
Affinity DataIC50: 0.0210nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Agriibrahim£E£En University

Curated by ChEMBL
LigandPNGBDBM50456682(CHEMBL4210041)
Affinity DataIC50: 0.0220nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Agriibrahim£E£En University

Curated by ChEMBL
LigandPNGBDBM50093586(CHEMBL3585778)
Affinity DataKi:  0.0230nMAssay Description:Inhibition of acetylcholinesterase (unknown origin) assessed as AChI hydrolysis using AChI and DTNB as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Pacific electric ray)
TBA

Curated by ChEMBL
LigandPNGBDBM50304322((1R,9R)-13-Eth-(E)-ylidene-1-{[1-(4-methoxy-phenyl...)
Affinity DataIC50: 0.0246nMAssay Description:Inhibition of Torpedo california AChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Agriibrahim£E£En University

Curated by ChEMBL
LigandPNGBDBM10597((1S)-7-chloro-15-ethyl-10-azatetracyclo[11.3.1.0^{...)
Affinity DataKi:  0.0260nM ΔG°:  -60.4kJ/molepH: 7.0 T: 2°CAssay Description:Assays were conducted at 25 C in 20 mM sodium phosphate buffer (pH 7.0) and 0.01% bovine serum albumin unless otherwise noted. AChE concentrations we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2014
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Agriibrahim£E£En University

Curated by ChEMBL
LigandPNGBDBM10597((1S)-7-chloro-15-ethyl-10-azatetracyclo[11.3.1.0^{...)
Affinity DataKi:  0.0260nM ΔG°:  -60.4kJ/molepH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by E llman. Inhibition of enzyme activity was measured over a substrate c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/5/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Agriibrahim£E£En University

Curated by ChEMBL
LigandPNGBDBM50456694(CHEMBL4205144)
Affinity DataIC50: 0.0260nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Agriibrahim£E£En University

Curated by ChEMBL
LigandPNGBDBM50456688(CHEMBL4218191)
Affinity DataIC50: 0.0260nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Agriibrahim£E£En University

Curated by ChEMBL
LigandPNGBDBM50369748(CHEMBL208599)
Affinity DataKi:  0.0260nMAssay Description:Inhibitory activity against human AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Agriibrahim£E£En University

Curated by ChEMBL
LigandPNGBDBM50093583(CHEMBL3585781)
Affinity DataIC50: 0.0270nMAssay Description:Inhibition of acetylcholinesterase (unknown origin) assessed as AChI hydrolysis using AChI and DTNB as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Agriibrahim£E£En University

Curated by ChEMBL
LigandPNGBDBM50093582(CHEMBL3585782)
Affinity DataIC50: 0.0270nMAssay Description:Inhibition of acetylcholinesterase (unknown origin) assessed as AChI hydrolysis using AChI and DTNB as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Agriibrahim£E£En University

Curated by ChEMBL
LigandPNGBDBM50093585(CHEMBL3585779)
Affinity DataIC50: 0.0270nMAssay Description:Inhibition of acetylcholinesterase (unknown origin) assessed as AChI hydrolysis using AChI and DTNB as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Agriibrahim£E£En University

Curated by ChEMBL
LigandPNGBDBM50093584(CHEMBL3585780)
Affinity DataIC50: 0.0270nMAssay Description:Inhibition of acetylcholinesterase (unknown origin) assessed as AChI hydrolysis using AChI and DTNB as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Agriibrahim£E£En University

Curated by ChEMBL
LigandPNGBDBM50093588(CHEMBL3585776)
Affinity DataIC50: 0.0270nMAssay Description:Inhibition of acetylcholinesterase (unknown origin) assessed as AChI hydrolysis using AChI and DTNB as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Agriibrahim£E£En University

Curated by ChEMBL
LigandPNGBDBM50093586(CHEMBL3585778)
Affinity DataIC50: 0.0270nMAssay Description:Inhibition of acetylcholinesterase (unknown origin) assessed as AChI hydrolysis using AChI and DTNB as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Agriibrahim£E£En University

Curated by ChEMBL
LigandPNGBDBM50093587(CHEMBL3585777)
Affinity DataIC50: 0.0270nMAssay Description:Inhibition of acetylcholinesterase (unknown origin) assessed as AChI hydrolysis using AChI and DTNB as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Agriibrahim£E£En University

Curated by ChEMBL
LigandPNGBDBM50093581(CHEMBL3585783)
Affinity DataIC50: 0.0270nMAssay Description:Inhibition of acetylcholinesterase (unknown origin) assessed as AChI hydrolysis using AChI and DTNB as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Agriibrahim£E£En University

Curated by ChEMBL
LigandPNGBDBM50093589(CHEMBL3585775)
Affinity DataIC50: 0.0270nMAssay Description:Inhibition of acetylcholinesterase (unknown origin) assessed as AChI hydrolysis using AChI and DTNB as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Agriibrahim£E£En University

Curated by ChEMBL
LigandPNGBDBM50093597(CHEMBL3585784)
Affinity DataIC50: 0.0270nMAssay Description:Inhibition of acetylcholinesterase (unknown origin) assessed as AChI hydrolysis using AChI and DTNB as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Agriibrahim£E£En University

Curated by ChEMBL
LigandPNGBDBM50456687(CHEMBL4208866)
Affinity DataIC50: 0.0280nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
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