Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with Target = 'ADP-sugar pyrophosphatase'
TargetADP-sugar pyrophosphatase(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50636312(CHEMBL5557167)
Affinity DataEC50:  2.5nMAssay Description:Antagonist activity at N-terminal his6-tagged human recombinant NUDT5 (1 to 208 residues) expressed in Escherichia coli Rosetta (DE3) expressed in HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetADP-sugar pyrophosphatase(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataKd:  200nMAssay Description:Binding affinity to N-terminal his6-tagged human recombinant NUDT5 (1 to 208 residues) expressed in Escherichia coli Rosetta (DE3) assessed as dissoc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetADP-sugar pyrophosphatase(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50636307(CHEMBL5527860)
Affinity DataKd:  250nMAssay Description:Binding affinity to N-terminal his6-tagged human recombinant NUDT5 (1 to 208 residues) expressed in Escherichia coli Rosetta (DE3) assessed as dissoc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetADP-sugar pyrophosphatase(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50636307(CHEMBL5527860)
Affinity DataIC50: 270nMAssay Description:Antagonist activity at N-terminal his6-tagged human recombinant NUDT5 (1 to 208 residues) expressed in Escherichia coli Rosetta (DE3) using ADP as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetADP-sugar pyrophosphatase(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50636308(CHEMBL5549952)
Affinity DataIC50: 487nMAssay Description:Antagonist activity at N-terminal his6-tagged human recombinant NUDT5 (1 to 208 residues) expressed in Escherichia coli Rosetta (DE3) using ADP as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetADP-sugar pyrophosphatase(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 830nMAssay Description:Antagonist activity at NUDT5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetADP-sugar pyrophosphatase(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 837nMAssay Description:Antagonist activity at N-terminal his6-tagged human recombinant NUDT5 (1 to 208 residues) expressed in Escherichia coli Rosetta (DE3) using ADP as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetADP-sugar pyrophosphatase(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50636307(CHEMBL5527860)
Affinity DataEC50:  1.08E+3nMAssay Description:Antagonist activity at N-terminal his6-tagged human recombinant NUDT5 (1 to 208 residues) expressed in Escherichia coli Rosetta (DE3) expressed in HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetADP-sugar pyrophosphatase(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataEC50:  1.23E+3nMAssay Description:Antagonist activity at N-terminal his6-tagged human recombinant NUDT5 (1 to 208 residues) expressed in Escherichia coli Rosetta (DE3) expressed in HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetADP-sugar pyrophosphatase(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50636309(CHEMBL1242204)
Affinity DataIC50: 2.04E+3nMAssay Description:Antagonist activity at N-terminal his6-tagged human recombinant NUDT5 (1 to 208 residues) expressed in Escherichia coli Rosetta (DE3) using ADP as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetADP-sugar pyrophosphatase(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50652792(CHEMBL3752910)
Affinity DataKd:  3.62E+3nMAssay Description:Binding affinity to human NUDT5 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetADP-sugar pyrophosphatase(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  7.68E+3nMAssay Description:Binding affinity to human NUDT5 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetADP-sugar pyrophosphatase(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50636306(CHEMBL4449342)
Affinity DataEC50: >1.00E+4nMAssay Description:Antagonist activity at N-terminal his6-tagged human recombinant NUDT5 (1 to 208 residues) expressed in Escherichia coli Rosetta (DE3) expressed in HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetADP-sugar pyrophosphatase(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM291627(1-(4-(((6-amino-5-(4-(phenylamino)phenyl)pyrimidin...)
Affinity DataEC50: >1.00E+4nMAssay Description:Antagonist activity at N-terminal his6-tagged human recombinant NUDT5 (1 to 208 residues) expressed in Escherichia coli Rosetta (DE3) expressed in HE...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetADP-sugar pyrophosphatase(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM164638(US9688629, 123 | BDBM166759 | US9802915, Example 1...)
Affinity DataEC50: >1.00E+4nMAssay Description:Antagonist activity at N-terminal his6-tagged human recombinant NUDT5 (1 to 208 residues) expressed in Escherichia coli Rosetta (DE3) expressed in HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetADP-sugar pyrophosphatase(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50175583(ACP-196 | Acalabrutinib | US9758524, Example 6 | U...)
Affinity DataEC50: >1.00E+4nMAssay Description:Antagonist activity at N-terminal his6-tagged human recombinant NUDT5 (1 to 208 residues) expressed in Escherichia coli Rosetta (DE3) expressed in HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetADP-sugar pyrophosphatase(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50636311(CHEMBL5549782)
Affinity DataIC50: 1.38E+4nMAssay Description:Antagonist activity at N-terminal his6-tagged human recombinant NUDT5 (1 to 208 residues) expressed in Escherichia coli Rosetta (DE3) using ADP as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetADP-sugar pyrophosphatase(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM291627(1-(4-(((6-amino-5-(4-(phenylamino)phenyl)pyrimidin...)
Affinity DataIC50: 1.39E+4nMAssay Description:Antagonist activity at N-terminal his6-tagged human recombinant NUDT5 (1 to 208 residues) expressed in Escherichia coli Rosetta (DE3) using ADP as su...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetADP-sugar pyrophosphatase(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50636306(CHEMBL4449342)
Affinity DataIC50: 2.12E+4nMAssay Description:Antagonist activity at N-terminal his6-tagged human recombinant NUDT5 (1 to 208 residues) expressed in Escherichia coli Rosetta (DE3) using ADP as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetADP-sugar pyrophosphatase(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50636310(CHEMBL5560485)
Affinity DataIC50: 5.00E+4nMAssay Description:Antagonist activity at N-terminal his6-tagged human recombinant NUDT5 (1 to 208 residues) expressed in Escherichia coli Rosetta (DE3) using ADP as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetADP-sugar pyrophosphatase(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50236118(CHEMBL4065181)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human His-tagged NUDT5 expressed in bacterial expression system in presence of ADP after 1 hr by malachite green reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2019
Entry Details Article
PubMed