Compile Data Set for Download or QSAR
Report error Found 7442 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 2C'
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50091835((R)-9-Chloro-8-trifluoromethyl-2,3,4,4a-tetrahydro...)
Affinity DataEC50:  19nMAssay Description:Binding affinity using [125I]DOI as radioligand with membranes isolated from a CHO-k cell line expressing the human 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50091827((S)-8,9-Dichloro-2,3,4,4a-tetrahydro-1H,6H-pyrazin...)
Affinity DataEC50:  290nMAssay Description:Binding affinity using [125I]DOI as radioligand with membranes isolated from a CHO-k cell line expressing the human 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50091829((R)-8,9-Dichloro-2,3,4,4a,5,6-hexahydro-1H-pyrazin...)
Affinity DataEC50:  49nMAssay Description:Binding affinity using [125I]DOI as radioligand with membranes isolated from a CHO-k cell line expressing the human 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50091825(8,9-Dichloro-2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,...)
Affinity DataEC50:  7.60nMAssay Description:Binding affinity using [125I]DOI as radioligand with membranes isolated from a CHO-k cell line expressing the human 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50088876(1N-methyl-2-(8-fluoro-4-methyl-5,6-dihydro-4H-pyrr...)
Affinity DataEC50:  180nMAssay Description:In vitro binding affinity towards human 5-hydroxytryptamine 2C receptor expressed in HEK293 cells was determined using [3H]mesulergine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50088871(2-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-...)
Affinity DataEC50:  0.200nMAssay Description:In vitro binding affinity towards human 5-hydroxytryptamine 2C receptor expressed in HEK293 cells was determined using [3H]mesulergine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50088875(2-(2-methyl-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinol...)
Affinity DataEC50:  9nMAssay Description:In vitro binding affinity towards human 5-hydroxytryptamine 2C receptor expressed in HEK293 cells was determined using [3H]mesulergine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50088874(2-(8-fluoro-2,4-dimethyl-5,6-dihydro-4H-pyrrolo[3,...)
Affinity DataEC50:  41nMAssay Description:In vitro binding affinity towards human 5-hydroxytryptamine 2C receptor expressed in HEK293 cells was determined using [3H]mesulergine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50144845((S)-2-(6-Chloro-5-fluoro-2,3-dihydro-indol-1-yl)-1...)
Affinity DataEC50:  31nMAssay Description:Affinity for human 5-hydroxytryptamine 2C receptor expressed in mammalian cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50144844((S)-1-Methyl-2-(2,3,8,9-tetrahydro-7H-pyrano[2,3-g...)
Affinity DataEC50:  28nMAssay Description:Affinity for human 5-hydroxytryptamine 2C receptor expressed in mammalian cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50144843((S)-2-(5-Fluoro-6-trifluoromethyl-2,3-dihydro-indo...)
Affinity DataEC50:  130nMAssay Description:Affinity for human 5-hydroxytryptamine 2C receptor expressed in mammalian cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50144839((S)-2-(6-Ethylsulfanyl-5-fluoro-2,3-dihydro-indol-...)
Affinity DataEC50:  21nMAssay Description:Affinity for human 5-hydroxytryptamine 2C receptor expressed in mammalian cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataEC50:  1.70nMAssay Description:Affinity for human 5-hydroxytryptamine 2C receptor expressed in mammalian cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50144842((S)-1-Methyl-2-(2,3,7,8-tetrahydro-furo[2,3-g]indo...)
Affinity DataEC50:  4.5nMAssay Description:Affinity for human 5-hydroxytryptamine 2C receptor expressed in mammalian cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50304819(4-(piperazin-1-yl)-7H-pyrrolo[2,3-d]pyrimidine | C...)
Affinity DataEC50:  755nMAssay Description:Agonist activity against human 5HT2C receptor by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50304803((R)-8-(2-chlorophenoxy)-2-(piperazin-1-yl)-5,6,7,8...)
Affinity DataEC50:  120nMAssay Description:Agonist activity against human 5HT2C receptor by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50304815(4-(piperazin-1-yl)thieno[3,2-d]pyrimidine | CHEMBL...)
Affinity DataEC50:  400nMAssay Description:Agonist activity against human 5HT2C receptor by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50304813(6-bromo-8-(piperazin-1-yl)imidazo[1,2-a]pyrazine |...)
Affinity DataEC50:  1.36E+3nMAssay Description:Agonist activity against human 5HT2C receptor by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50304809(4-(3-chlorobenzyloxy)-2-(piperazin-1-yl)thieno[2,3...)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity against human 5HT2C receptor by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50304820(2-(piperazin-1-yl)-5,6,7,8-tetrahydroquinoline | C...)
Affinity DataEC50:  25nMAssay Description:Agonist activity against human 5HT2C receptor by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50016970(CHEMBL608135 | CHEMBL552833 | 4-Piperazin-1-yl-thi...)
Affinity DataEC50:  187nMAssay Description:Agonist activity against human 5HT2C receptor by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50304806((R)-7-(2-chlorophenoxy)-2-(piperazin-1-yl)-6,7-dih...)
Affinity DataEC50:  22nMAssay Description:Agonist activity against human 5HT2C receptor by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50304801((S)-7-(2,5-difluorobenzyloxy)-2-((R)-2-methylpiper...)
Affinity DataEC50:  1nMAssay Description:Agonist activity against human 5HT2C receptor by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataEC50:  2.40E+4nMAssay Description:Effect on phosphoinositide hydrolysis in NIH 3T3 fibroblast 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059890(2-(8-Methoxy-2,3,5,6-tetrahydro-benzo[1,2-b;5,4-b'...)
Affinity DataEC50:  1.00E+3nMAssay Description:Effect on phosphoinositide hydrolysis in NIH 3T3 fibroblast 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059892(2-(6,7-Dimethoxy-2,3-dihydro-benzofuran-4-yl)-ethy...)
Affinity DataEC50:  2.00E+3nMAssay Description:Effect on phosphoinositide hydrolysis in NIH 3T3 fibroblast 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059893(2-(4-Ethoxy-3,5-dimethoxy-phenyl)-ethylamine | CHE...)
Affinity DataEC50:  2.00E+3nMAssay Description:Effect on phosphoinositide hydrolysis in NIH 3T3 fibroblast 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50091824((S)-9-Chloro-8-trifluoromethyl-2,3,4,4a-tetrahydro...)
Affinity DataEC50:  2.60E+3nMAssay Description:Agonistic activity for 5-HT2c (5-HT2C) by measuring [3H]inositol monophosphate fromation in CHO cells in which the human 5-HT2C receptor subtype was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50091831((R)-8,9-Dichloro-2,3,4,4a-tetrahydro-1H,6H-pyrazin...)
Affinity DataEC50:  8nMAssay Description:Agonistic activity for 5-HT2c (5-HT2C) by measuring [3H]inositol monophosphate fromation in CHO cells in which the human 5-HT2C receptor subtype was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50091822(8,9-Dichloro-2,3,4,4a-tetrahydro-1H,6H-pyrazino[1,...)
Affinity DataEC50:  12nMAssay Description:Agonistic activity for 5-HT2c (5-HT2C) by measuring [3H]inositol monophosphate fromation in CHO cells in which the human 5-HT2C receptor subtype was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50091830(9-Chloro-8-trifluoromethyl-2,3,4,4a-tetrahydro-1H,...)
Affinity DataEC50:  136nMAssay Description:Agonistic activity for 5-HT2c (5-HT2C) by measuring [3H]inositol monophosphate fromation in CHO cells in which the human 5-HT2C receptor subtype was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50091821((R)-9-Chloro-2,3,4,4a-tetrahydro-1H,6H-pyrazino[1,...)
Affinity DataEC50:  86nMAssay Description:Binding affinity using [125I]DOI as radioligand with membranes isolated from a CHO-k cell line expressing the human 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50091826((S)-8,9-Dichloro-2,3,4,4a,5,6-hexahydro-1H-pyrazin...)
Affinity DataEC50:  45nMAssay Description:Binding affinity using [125I]DOI as radioligand with membranes isolated from a CHO-k cell line expressing the human 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50091834((R)-9-Chloro-8-trifluoromethyl-2,3,4,4a,5,6-hexahy...)
Affinity DataEC50:  19nMAssay Description:Binding affinity using [125I]DOI as radioligand with membranes isolated from a CHO-k cell line expressing the human 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50144838((S)-2-(5-Fluoro-6-iodo-2,3-dihydro-indol-1-yl)-1-m...)
Affinity DataEC50:  64nMAssay Description:Functional activity against human 5-hydroxytryptamine 2C receptor expressed in CHO cells using fluorometric imaging plate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50144841((S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-am...)
Affinity DataEC50:  18nMAssay Description:Functional activity against human 5-hydroxytryptamine 2C receptor expressed in CHO cells using fluorometric imaging plate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50144846(VER-5593 | (S)-2-(5-Fluoro-6-methylsulfanyl-2,3-di...)
Affinity DataEC50:  6.70nMAssay Description:Functional activity against human 5-hydroxytryptamine 2C receptor expressed in CHO cells using fluorometric imaging plate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50144835((S)-1-Methyl-2-(6-methylsulfanyl-2,3-dihydro-indol...)
Affinity DataEC50:  26nMAssay Description:Functional activity against human 5-hydroxytryptamine 2C receptor expressed in CHO cells using fluorometric imaging plate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50144836((S)-2-(6-Ethylsulfanyl-2,3-dihydro-indol-1-yl)-1-m...)
Affinity DataEC50:  40nMAssay Description:Affinity for human 5-hydroxytryptamine 2C receptor expressed in mammalian cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50144837((S)-2-(6-Chloro-2,3-dihydro-indol-1-yl)-1-methyl-e...)
Affinity DataEC50:  44nMAssay Description:Affinity for human 5-hydroxytryptamine 2C receptor expressed in mammalian cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50144840(CHEMBL309760 | (S)-2-(6-Bromo-2,3-dihydro-indol-1-...)
Affinity DataEC50:  44nMAssay Description:Affinity for human 5-hydroxytryptamine 2C receptor expressed in mammalian cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50001915(mCPP | 1-(3-chlorophenyl)piperazine | CHEMBL478 | ...)
Affinity DataEC50:  26nMAssay Description:Affinity for human 5-hydroxytryptamine 2C receptor expressed in mammalian cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50161619(7-Methoxy-1-methyl-8-trifluoromethyl-2,3,4,5-tetra...)
Affinity DataEC50:  4nMAssay Description:Effective concentration towards 5-hydroxytryptamine 2C receptors transfected in HEK293 cells was determined by measuring [3H]phosphoinositol releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50161622(8-Bromo-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]aze...)
Affinity DataEC50:  12nMAssay Description:Effective concentration towards 5-hydroxytryptamine 2C receptors transfected in HEK293 cells was determined by measuring [3H]phosphoinositol releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50161626(8-Bromo-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]aze...)
Affinity DataEC50:  3nMAssay Description:Effective concentration towards 5-hydroxytryptamine 2C receptors transfected in HEK293 cells was determined by measuring [3H]phosphoinositol releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50161634((1R)-8,9-dichloro-2,3,4,5-tetrahydro-1-methyl-1H-3...)
Affinity DataEC50:  230nMAssay Description:Effective concentration towards 5-hydroxytryptamine 2C receptors transfected in HEK293 cells was determined by measuring [3H]phosphoinositol releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50161636((1S)-8,9-dichloro-2,3,4,5-tetrahydro-1-methyl-1H-3...)
Affinity DataEC50:  3nMAssay Description:Effective concentration towards 5-hydroxytryptamine 2C receptors transfected in HEK293 cells was determined by measuring [3H]phosphoinositol releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50161638((1R,S)-8-chloro-7-methoxy-2,3,4,5-tetrahydro-1-met...)
Affinity DataEC50:  11nMAssay Description:Effective concentration towards 5-hydroxytryptamine 2C receptors transfected in HEK293 cells was determined by measuring [3H]phosphoinositol releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50161625(1-Methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine | C...)
Affinity DataEC50:  340nMAssay Description:Effective concentration towards 5-hydroxytryptamine 2C receptors transfected in HEK293 cells was determined by measuring [3H]phosphoinositol releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50161640(8-Bromo-1-isopropyl-7-methoxy-2,3,4,5-tetrahydro-1...)
Affinity DataEC50:  160nMAssay Description:Effective concentration towards 5-hydroxytryptamine 2C receptors transfected in HEK293 cells was determined by measuring [3H]phosphoinositol releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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