Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with Target = '5'-AMP-activated protein kinase subunit beta-2'
LigandPNGBDBM50195534(CHEMBL3957286)
Affinity DataEC50:  4nMAssay Description:Activation of human recombinant AMPK alpha2/beta2/gamma3 expressed in African green monkey COS7 cells assessed as increase in biotinylated AAC (1 to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2018
Entry Details Article
PubMed
LigandPNGBDBM50195479(CHEMBL3950376)
Affinity DataEC50: <5.00E+3nMAssay Description:Activation of human recombinant AMPK beta2 expressed in African green monkey COS7 cells or baculovirus infected insect cells assessed as increase in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2018
Entry Details Article
PubMed
LigandPNGBDBM237920(US9394285, 1)
Affinity DataEC50: >4.00E+4nMAssay Description:Activation of recombinant human AMPK alpha2/beta2/gamma3 by using Cy5-labelled SAMS as substrate in presence of ATP by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2018
Entry Details Article
PubMed
LigandPNGBDBM50246120(CHEMBL4082745)
Affinity DataEC50:  35nMAssay Description:Agonist activity at human recombinant phosphorylated AMPK complex 12 alpha2/beta2/gamma3 expressed in baculovirus infected Sf21 cells assessed as pho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
LigandPNGBDBM238079(US9394285, 173)
Affinity DataEC50: >4.00E+4nMAssay Description:Activation of full-length recombinant N-terminal His-tagged human AMPKalpha2beta2gamma3 expressed in Escherichia coli BL21 cells using Cy-5 SAMS pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
LigandPNGBDBM237920(US9394285, 1)
Affinity DataEC50: >4.00E+4nMAssay Description:Activation of full-length recombinant N-terminal His-tagged human AMPKalpha2beta2gamma3 expressed in Escherichia coli BL21 cells using Cy-5 SAMS pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
LigandPNGBDBM50463101(CHEMBL4250253)
Affinity DataEC50: >4.00E+4nMAssay Description:Activation of full-length recombinant N-terminal His-tagged human AMPKalpha2beta2gamma3 expressed in Escherichia coli BL21 cells using Cy-5 SAMS pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
LigandPNGBDBM50244667(CHEMBL4105032)
Affinity DataEC50: >4.00E+4nMAssay Description:Activation of full-length recombinant N-terminal His-tagged human AMPKalpha2beta2gamma3 expressed in Escherichia coli BL21 cells using Cy-5 SAMS pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
LigandPNGBDBM50463100(CHEMBL4249790)
Affinity DataEC50: >4.00E+4nMAssay Description:Activation of full-length recombinant N-terminal His-tagged human AMPKalpha2beta2gamma3 expressed in Escherichia coli BL21 cells using Cy-5 SAMS pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
LigandPNGBDBM50463099(CHEMBL4246000)
Affinity DataEC50: >4.00E+4nMAssay Description:Activation of full-length recombinant N-terminal His-tagged human AMPKalpha2beta2gamma3 expressed in Escherichia coli BL21 cells using Cy-5 SAMS pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
LigandPNGBDBM50600528(CHEMBL5191686)
Affinity DataEC50:  1.30E+3nMAssay Description:Activation of recombinant AMPK-beta2 (unknown origin) assessed as increase in AMPK phosphorylation by DELFIA fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM50652792(CHEMBL3752910)
Affinity DataKd:  32nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target5'-AMP-activated protein kinase subunit beta-2(Rat)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataIC50: 62nMAssay Description:Inhibition of rat AMPKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
Target5'-AMP-activated protein kinase subunit beta-2(Rat)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50262685(CHEMBL478629 | 6-(4-(2-(piperidin-1-yl)ethoxy)phen...)
Affinity DataIC50: 1.28E+3nMAssay Description:Inhibition of rat AMPKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)