Compile Data Set for Download or QSAR
Report error Found 296 Enz. Inhib. hit(s) with Target = '2-acylglycerol O-acyltransferase 2'
Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50652958(CHEMBL5687004)
Affinity DataIC50: 0.25nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50652960(CHEMBL5687021)
Affinity DataIC50: 0.420nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50652959(CHEMBL5687051)
Affinity DataIC50: 0.690nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50617831(CHEMBL5434664)
Affinity DataIC50: 1nMAssay Description:Inhibition of human MGAT2 by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50090510(CHEMBL3581716)
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target2-acylglycerol O-acyltransferase 2(Mouse)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50652963(CHEMBL5686988)
Affinity DataIC50: 1.10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target2-acylglycerol O-acyltransferase 2(Mouse)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50652964(CHEMBL5687022)
Affinity DataIC50: 1.90nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM159725(US9035059, 19-4)
Affinity DataIC50: 2nMAssay Description:A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2015
Entry Details
Go to US Patent

Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50442175(CHEMBL2441597)
Affinity DataIC50: 2nMAssay Description:Inhibition of human MGAT2 by LC/MS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50518069(CHEMBL4542050 | US11479538, Example 22)
Affinity DataIC50: 2nMAssay Description:The MGAT enzyme reactions were performed in Corning FALCON 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50617810(CHEMBL5422037)
Affinity DataIC50: 2nMAssay Description:Inhibition of human MGAT2 by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50617826(CHEMBL5415437)
Affinity DataIC50: 2nMAssay Description:Inhibition of human MGAT2 by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50617828(CHEMBL5424834)
Affinity DataIC50: 2nMAssay Description:Inhibition of human MGAT2 by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50652963(CHEMBL5686988)
Affinity DataIC50: 2.10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target2-acylglycerol O-acyltransferase 2(Mouse)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50518060(CHEMBL4455357)
Affinity DataIC50: 2.40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM289043(US10093650, Example 20 | US10329273, Example 20 | ...)
Affinity DataIC50: 3nMAssay Description:The MGAT enzyme reactions were performed in Corning FALCON 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Target2-acylglycerol O-acyltransferase 2(Mouse)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50617826(CHEMBL5415437)
Affinity DataIC50: 3nMAssay Description:Inhibition of mouse MGAT2 by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
Target2-acylglycerol O-acyltransferase 2(Mouse)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50617828(CHEMBL5424834)
Affinity DataIC50: 3nMAssay Description:Inhibition of mouse MGAT2 by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50090617(CHEMBL3581734)
Affinity DataIC50: 3.40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50652964(CHEMBL5687022)
Affinity DataIC50: 3.70nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50058840(CHEMBL3325734)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of human MoGAT-2 expressed in human Caco2 cells assessed as inhibition of 2-O-Hexadecylglycerol hydrolysis pretreated for 30 mins by LC-MS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM159724(US9035059, 19-3)
Affinity DataIC50: 4nMAssay Description:A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2015
Entry Details
Go to US Patent

Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM159734(US9035059, 24-1/24-2 | US9035059, 23-1)
Affinity DataIC50: 4nMT: 2°CAssay Description:An MGAT2 inhibition test for test compounds was conducted in accordance with a partially modified version of the method described in John F. Lockwood...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2015
Entry Details
Go to US Patent

Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50652953(CHEMBL5686997)
Affinity DataIC50: 4.10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM159732(US9035059, 20-4)
Affinity DataIC50: 5nMT: 2°CAssay Description:An MGAT2 inhibition test for test compounds was conducted in accordance with a partially modified version of the method described in John F. Lockwood...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2015
Entry Details
Go to US Patent

Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM38176(US10093650, Example 2 | US10329273, Example 2 | US...)
Affinity DataIC50: 5nMAssay Description:The MGAT enzyme reactions were performed in Corning FALCON 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM289003(US10093650, Example 16 | US10093650, Example 14 | ...)
Affinity DataIC50: 5nMAssay Description:The MGAT enzyme reactions were performed in Corning FALCON 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM400245(US10329273, Example 16 | US11479538, Example 16)
Affinity DataIC50: 5nMAssay Description:The MGAT enzyme reactions were performed in Corning FALCON 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM289021(US10093650, Example 17 | BDBM400246)
Affinity DataIC50: 5nMAssay Description:The MGAT enzyme reactions were performed in Corning FALCON 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Target2-acylglycerol O-acyltransferase 2(Mouse)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50617821(CHEMBL5406388)
Affinity DataIC50: 5nMAssay Description:Inhibition of mouse MGAT2 by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50617820(CHEMBL5411014)
Affinity DataIC50: 5nMAssay Description:Inhibition of human MGAT2 by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50617821(CHEMBL5406388)
Affinity DataIC50: 5nMAssay Description:Inhibition of human MGAT2 by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
Target2-acylglycerol O-acyltransferase 2(Mouse)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50617825(CHEMBL5435045)
Affinity DataIC50: 6nMAssay Description:Inhibition of mouse MGAT2 by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50652961(CHEMBL5687019)
Affinity DataIC50: 6.20nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM159705(US9035059, 18-7)
Affinity DataIC50: 7nMAssay Description:A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2015
Entry Details
Go to US Patent

Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50442176(CHEMBL2441598)
Affinity DataIC50: 7nMAssay Description:Inhibition of human MGAT2 by LC/MS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50442178(CHEMBL2441600 | US9187424, 124)
Affinity DataIC50: 7nMAssay Description:Inhibition of human MGAT2 by LC/MS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
Target2-acylglycerol O-acyltransferase 2(Mouse)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50617808(CHEMBL5414175)
Affinity DataIC50: 7nMAssay Description:Inhibition of mouse MGAT2 by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50518060(CHEMBL4455357)
Affinity DataIC50: 7.80nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50442175(CHEMBL2441597)
Affinity DataIC50: 8nMAssay Description:Inhibition of human MGAT2 by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM289026(US10093650, Example 18 | US10329273, Example 18 | ...)
Affinity DataIC50: 8nMAssay Description:The MGAT enzyme reactions were performed in Corning FALCON 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Target2-acylglycerol O-acyltransferase 2(Mouse)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50617832(CHEMBL5401316)
Affinity DataIC50: 8nMAssay Description:Inhibition of mouse MGAT2 by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50617825(CHEMBL5435045)
Affinity DataIC50: 8nMAssay Description:Inhibition of human MGAT2 by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50617832(CHEMBL5401316)
Affinity DataIC50: 8nMAssay Description:Inhibition of human MGAT2 by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50652962(CHEMBL5687034)
Affinity DataIC50: 8.20nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50442176(CHEMBL2441598)
Affinity DataIC50: 9nMAssay Description:Inhibition of human MGAT2 by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM211296(US10093650, Example 11 | US10329273, Example 11 | ...)
Affinity DataIC50: 9nMAssay Description:The MGAT enzyme reactions were performed in Corning FALCON 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50617830(CHEMBL5413599)
Affinity DataIC50: 9nMAssay Description:Inhibition of human MGAT2 by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM159711(US9035059, 18-16)
Affinity DataIC50: 10nMAssay Description:A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2015
Entry Details
Go to US Patent

Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM159740(US9035059, 24-11 | US9035059, 24-5/24-6)
Affinity DataIC50: 10nMT: 2°CAssay Description:An MGAT2 inhibition test for test compounds was conducted in accordance with a partially modified version of the method described in John F. Lockwood...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2015
Entry Details
Go to US Patent

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