Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with Target = '2',5'-phosphodiesterase 12'
Target2',5'-phosphodiesterase 12(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  7.11E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target2',5'-phosphodiesterase 12(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50532283(CHEMBL4556129)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human PDE12 (17 to 609 residues) expresssed in Escherichia coli BL21(DE3) cells using 2-5A as substrate assessed as AMP monomers and AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
Target2',5'-phosphodiesterase 12(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50532283(CHEMBL4556129)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human PDE12 (17 to 609 residues) expresssed in Escherichia coli BL21(DE3) cells using 2-5A as substrate assessed as AMP monomers and AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
Target2',5'-phosphodiesterase 12(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50365463(CHEMBL1232461)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target2',5'-phosphodiesterase 12(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50618273(CHEMBL5415518)
Affinity DataKi:  18nMAssay Description:Binding affinity to PDE12 (unknown origin) (17 to 609 residues) assessed as inhibition constant by AMP-glo reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed