Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with Target = '14-3-3 protein sigma'
Target14-3-3 protein sigma(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50356015(CHEMBL1911376)
Affinity DataKd: >1.00E+3nMAssay Description:Binding affinity to histidine-tagged human recombinant 14-3-3sigma by transferred NOESY analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
Target14-3-3 protein sigma(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50462078(CHEMBL4243744)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of TMR-GG-RLSHpSSLPG-NH2 binding to recombinant human GST-tagged 14-3-3-sigma preincubated for 30 mins followed by TMR-GG-RLSHpSSLPG-NH2 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
Target14-3-3 protein sigma(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50462080(CHEMBL4250552)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of TMR-GG-RLSHpSSLPG-NH2 binding to recombinant human GST-tagged 14-3-3-sigma preincubated for 30 mins followed by TMR-GG-RLSHpSSLPG-NH2 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
Target14-3-3 protein sigma(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50462083(CHEMBL4237531)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of TMR-GG-RLSHpSSLPG-NH2 binding to recombinant human GST-tagged 14-3-3-sigma preincubated for 30 mins followed by TMR-GG-RLSHpSSLPG-NH2 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
Target14-3-3 protein sigma(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50462084(CHEMBL4247540)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of TMR-GG-RLSHpSSLPG-NH2 binding to recombinant human GST-tagged 14-3-3-sigma preincubated for 30 mins followed by TMR-GG-RLSHpSSLPG-NH2 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
Target14-3-3 protein sigma(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50462085(CHEMBL4240436)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of TMR-GG-RLSHpSSLPG-NH2 binding to recombinant human GST-tagged 14-3-3-sigma preincubated for 30 mins followed by TMR-GG-RLSHpSSLPG-NH2 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
Target14-3-3 protein sigma(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50177030(CHEMBL3813927)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of 14-3-3sigma (unknown origin) assessed as reduction in 14-3-3sigma- mediated increase in MMP1 mRNA by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)