BDBM92624 Dimethoxyquinoline, 1

SMILES COc1cc2c(ccnc2cc1OC)Oc3ccc(nc3)NC(=O)N[C@@H]4C[C@H]4c5ccccc5

InChI Key InChIKey=MRWNNBQFJVSSHG-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 92624   

TargetTyrosine-protein kinase SYK(Human)
Pfizer

LigandPNGBDBM92624(Dimethoxyquinoline, 1)
Affinity DataIC50: 320nMpH: 7.4 T: 2°CAssay Description:A Lance TR-FRET assay (Perkin Elmer) was used to measure and compare the potency of compounds against Syk kinase domain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)